Toldin ER 600 Tablet (Etodolac 600mg)

INTRODUCTION

TOLDIN ER 600 MG contains Etodolac which belongs to the group of medicine called non-steroidal anti-inflammatory drugs. It is indicated in the treatment of signs and symptoms of rheumatoid arthritis and osteoarthritis by reducing joint pain, stiffness, inflammation and swelling. Rheumatoid arthritis is a chronic progressive bone disease which causes inflammation of the joints leading to pain, stiffness and deformity. It happens normally in the fingers, wrists, feet, and ankles. Osteoarthritis is a common bone degenerative disease predominant at middle age in which the joint cartilage and the underlying bone wears off, leading to pain and stiffness. It happens especially in the hip, knee and thumb joints.

TOLDIN ER 600 MG works by blocking the synthesis of prostaglandin and other powerful inflammatory mediators of arachidonic acid involved in causing pain, inflammation and swelling. This medicine can be taken with or without food. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

This medicine has a high potential to cause gastrointestinal disorders such as bleeding, ulceration and perforation at any time with or without warning symptoms. If any sign of GI bleeding occurs, stop taking this medicine and consult your doctor immediately. Avoid consumption of alcohol while taking this medicine as it could aggravate the GI side effects. The most common side effects of taking this medicine are dizziness, nausea, diarrhea, stomach pain and heartburn. Contact your doctor if any of these symptom bothers you.

Before taking this medicine, inform your doctor if you have any liver, kidney or heart disease. TOLDIN ER 600 MG is highly contraindicated in patients having or previously had any GI problems such as ulcers or bleeding. This medicine is not recommended for use in pregnant or breastfeeding women and in children (under 18 years) unless recommended by your doctor.

USES OF TOLDIN ER 600MG

Relieves pain, stiffness, inflammation and swelling associated with:

Rheumatoid arthritis
Osteoarthritis

HOW TOLDIN ER 600MG WORKS

Etodolac is non-steroidal anti-inflammatory medicine. It has anti-inflammatory, analgesic, and antipyretic activities. It acts by inhibiting the activity of the enzyme cyclooxygenase (COX) leading to the inhibition of prostaglandin synthesis and other powerful inflammatory mediators involved in causing pain, inflammation and swelling.

Related Product

DIRECTIONS FOR USE

Take this medicine as directed by your physician. It can be taken with or without food. Swallow the medicine as whole with a sip of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF TOLDIN ER 600MG

SERIOUS
Severe allergic reactions (such as skin rash, itching, peeling or blistering of skin, swelling of the face, lips, mouth or tongue and difficulty in breathing)
Heart problems (heart failure, chest pain, palpitations, high blood pressure)
Anemia, unexpected bleeding or bruising
Vomiting blood
Blood in stools or black tarry stools
Pain while urination, passing more or less urine than usual
Jaundice (yellowing of skin and eyes), stomach pain
Inflammation of pancreas
Signs of aseptic meningitis (fever, vomiting, headache, neck stiffness, dislike of bright lights, drowsiness and fits)
COMMON
Dizziness
Tinnitus (ringing in the ears)
Nausea, diarrhea, flatulence, heartburn or gastric pain
Fluid retention (edema)
General discomfort

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Flatulence:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor immediately.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Skin rash:

Avoid hot showers because hot water can irritate the skin. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If the symptom still persists, contact your doctor.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling dizzy. If the symptom still persists, contact your doctor for advice.

WARNING & PRECAUTIONS

PREGNANCY
TOLDIN ER 600MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING
TOLDIN ER 600MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES
Do not drive or operate any machines while taking this medicine, because it may cause dizziness, drowsiness or abnormal vision.

ALCOHOL
Avoid consumption of alcohol while taking this medicine.

KIDNEY
TOLDIN ER 600MG is not recommended for use in patients suffering from severe kidney problems (e.g. kidney failure). Consult your doctor for advice before taking.

LIVER
TOLDIN ER 600MG is not recommended for use in patients suffering from severe liver problems (e.g. liver failure). Consult your doctor for advice before taking.

ALLERGY
Do not take this medicine if you are allergic to etodolac, aspirin or other NSAIDS.

LUNGS
TOLDIN ER 600MG should be taken with caution in patients who have or had suffered from asthma or any other breathing difficulties. Consult your doctor for advice before taking.

HEART DISEASE
TOLDIN ER 600MG is not recommended for use in patients suffering from severe heart failure or high blood pressure. Consult your doctor for advice.

OTHERS

Before taking TOLDIN ER 600MG, inform your doctor if you:

Have a blood disorder
Have fluid retention, (swelling of legs, ankles or feet)
Have diabetes
Have high cholesterol levels in blood
Had previous stroke
Are a smoker

INTERACTIONS

Talk to your doctor, if you are taking,

Other non-steroidal anti-inflammatory drugs (e.g. aspirin, diclofenac, ibuprofen and naproxen)
Medicines used for high blood pressure (e.g. captopril, enalapril, losartan, propranolol)
Medicines used to treat depression (e.g. fluoxetine, sertraline, lithium)
Warfarin and heparin (used to prevent blood clots)
Ciclosporin (used to prevent graft rejection)
Digoxin (used to treat irregular heartbeat or heart failure)
Lithium (used to treat manic depression)
Methotrexate (used to treat psoriasis or rheumatoid arthritis)
Corticosteroids (used to treat allergy and inflammatory conditions) e.g. prednisolone
Quinolone antibiotics (used to treat bacterial infections) e.g. ciprofloxacin, sparfloxacin
Mifepristone (a medicine used to induce abortion)