Rabifast-XL Capsule (Levosulpiride 75mg /Rabeprazole 20mg)

About Rabifast XL Capsule

Rabifast XL Capsule belongs to a group of combination medication called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus), thereby causing hyperacidity, stomach pain and heartburn.

Rabifast XL Capsule is a combination of two drugs: Levosulpiride (prokinetic agent) and Rabeprazole (proton pump inhibitor). Levosulpiride works by increasing the inferior oesophageal (food pipe) sphincter pressure, thereby preventing backflow of food and acid into the mouth. Rabeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. Together, Rabifast XL Capsule helps in preventing acid reflux, thereby provides relief from acidity and heartburn.

Take Rabifast XL Capsule 1-hour prior food. Swallow Rabifast XL Capsule as a whole with a glass of water; do not chew, or break it. You are advised to take Rabifast XL Capsule for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, stomach pain, diarrhoea, flatulence, constipation, headache, dizziness, weakness, sleepiness, flu-like symptoms. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Rabifast XL Capsule if you have a history of gastrointestinal bleeding or intestinal obstruction. On long term treatment, Rabifast XL Capsule may cause osteoporosis-related fractures of the hip, wrist, spine, and hypomagnesemia (low magnesium levels). Do not take Rabifast XL Capsule if you are pregnant or breastfeeding. Rabifast XL Capsule should not be given to children as safety have not been established. Rabifast XL Capsule may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol and Rabifast XL Capsule as it could lead to increased drowsiness and elevate stomach acid production.

Uses of Rabifast XL Capsule

Gastro Esophageal reflux disease (GERD), Heartburn, Hyperacidity

Medicinal Benefits

Rabifast XL Capsule belongs to a group of gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Rabifast XL Capsule is a combination of two drugs: Levosulpiride (prokinetic agent) and Rabeprazole (proton pump inhibitor). Levosulpiride works by increasing the inferior oesophageal (food pipe) sphincter pressure, thereby preventing backflow of food and acid into the mouth. Rabeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. Collectively, Rabifast XL Capsule helps in preventing acid reflux, thereby provides relief from acidity and heartburn.

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Directions for Use

Take Rabifast XL Capsule 1hour prior food. Do not chew or crush it, swallow it as a whole with a glass of water. Depending on your medical condition, your doctor will decide how long you need to take Rabifast XL Capsule.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rabifast XL Capsule

• Headache
• Stomach pain
• Constipation
• Flatulence
• Diarrhoea
• Nausea
• Vomiting

In-Depth Precautions and Warning

Drug Warnings

Do not take Rabifast XL Capsule if you are allergic to any of its contents, have a gastrointestinal hemorrhage, epilepsy, mania, porphyria or cardiac impairment. Inform your doctor before taking Rabifast XL Capsule if you have stomach pain, indigestion, vomiting food or blood, or if you pass black stools,  have severe liver or kidney problems, if you are due to have Chromogranin A test. Do not take Rabifast XL Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Rabifast XL Capsule should not be given to children as safety have not been established. On long-term treatment, Rabifast XL Capsule may cause low magnesium levels, vitamin B12 levels and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Rabifast XL Capsule may cause dizziness and drowsiness, so drive only if you are alert. Avoid consuming alcohol along with Rabifast XL Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug Interactions

Drug-Drug Interactions: Rabifast XL Capsule may have interaction with painkillers (aspirin, naproxen), anti-HIV (atazanavir, nelfinavir, saquinavir), anti-cancer (erlotinib, methotrexate), blood thinner (clopidogrel, warfarin, cilostazol), anti-fungal (ketoconazole, itraconazole, voriconazole), antiparkinsons (levodopa), antihypertensive (captopril, enalapril, lisinopril) anti-depressant (citalopram, amitriptyline, imipramine, clomipramine, duloxetine), anti-anxiety (diazepam, alprazolam), anti-convulsant (phenytoin), gastroprokinetic agent (cisapride), a drug used to treat heart problems (digoxin), immunosuppressant (tacrolimus), anti-tuberculosis (rifampicin), antibiotics (clarithromycin, amoxicillin).

Food-Drug Interactions: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn. Rabifast XL Capsule may have interaction with St.John’s wort (herbal supplement used to treat depression). 

Drug-Disease Interaction: Rabifast XL Capsule may have interactions with gastrointestinal bleeding, intestinal obstruction, pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).