Rabez D Capsule (Domperidone 30mg / Rabeprazole 20mg)

Medical Description

Rabez D Capsule is an anti-reflux medicine. It is used for the treatment of GERD (Gastroesophageal reflux disease). GERD is a condition where acid from the stomach flows back to the food pipe. The backflow of acid irritates the lining of the food pipe and leads to chest pain and heartburn. It contains two medicines – rabeprazole and domperidone. The combination is used in patients in which rabeprazole alone is not able to control acid reflux. Rabez D Capsule must be taken as directed by the doctor and in doses and duration as prescribed. It must be taken before meals.

Uses of Rabez D Capsule

It is used to treat gastrointestinal reflux disease. It leads to acid regurgitating from the stomach into the food pipe, causing heartburn, chest discomfort and acidity.

Contraindications of Rabez D Capsule

If you are allergic to the medicine or other ingredients of the medicine.
If you are taking medications that affect the contraction of the heart muscle (QT prolongation).
If you suffer bleeding in the digestive system.
If you suffer from liver or kidney disorder.
If you have heart problems like congestive heart failure, heart rhythm problems, electrolyte imbalance.
If you have a tumour in the pituitary gland (Prolactin pituitary tumours).
If you are pregnant or breastfeeding.

Side effects of Rabez D Capsule

Nausea
Headache
Lack of energy
Gas
Skin rash
Diarrhoea
Dry mouth
Stomach pain
Sleeplessness
Back pain
Throat infection (Pharyngitis)
Cough
Vomiting
Dizziness

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Other General Warnings

Talk to your doctor if
You develop watery diarrhoea, fever after taking the medicine.
You experience black stools.
You have a stomach tumour.
You have a history of fractures or have osteoporosis or taking steroids.
You have liver and kidney disease or kidney failure.
You have heart problems and symptoms like palpitations, difficulty in breathing, unconsciousness.
You are on the medicine for more than three months. Your blood magnesium levels may drop. The doctor asks to perform regular tests for the same.
You are taking medicines to treat HIV.
You must not give the medicine to children of 12 years and below.
You have low levels of vitamin B12. The medicine reduces the absorption of vitamin B12 after long term use. Supplements may be needed.
Taking the medicine for more than one year may increase the chances of developing bone fractures.

Mode of Action of Rabez D Capsule

How Does It Work?
Rabeprazole belongs to the medicines called proton pump inhibitors. The lining of the stomach secretes acid by certain processes that involve the intake of ions via a proton pump in the cells. Rabeprazole reduces the intake of the ions in the stomach cells that are necessary for the production of digestive acids in the stomach and leads to reduced acid production.
Domperidone increases the motility of the stomach and intestines thus acid does not reflux back into the food pipe.

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Directions for Use of Rabez D Capsule
It must be taken as a whole with a glass of water (and must not be chewed or crushed), take in the morning before food.

Interactions of Rabez D Capsule

Interactions with other medicines
Medicines affect the way Rabez D capsule works or Rabez D capsule itself affects the action of other medicines taken at the same time.
Inform the physician about the medicines, supplements or herbals you are taking or might take to avoid possible interaction.
Taking medicines like Rilpivirine (Anti-HIV medications), Disopyramide (for irregular heart beats), medicines for mental problems, antibiotics, antifungals, a medicine used to treat heart failure like digoxin, blood thinners, etc.
Interactions with food items
You have to avoid spicy foods, smoking, reduce caffeine intake (coffee, tea, chocolate and cola) and alcohol as it stimulates stomach acid and hinders the treatment process.

Storage and disposal of Rabez D Capsule

Store below 25°C, protect from moisture and sunlight.
Keep the medicine away from children.

Dosage of Rabez D Capsule

Overdose
Symptoms of an overdose of Rabez-D include abnormal muscle movements, drowsiness, slurred speech and feel anxiety. If you have consumed too much of the medicine, contact the doctor or visit the nearest hospital.
Missed a Dose
If you have missed taking a dose, then take it as soon as you remember. If it’s time for the next dose, skip the missed dose and continue with the regular dosing schedule. Avoid taking a double dose of medicine to compensate for the missed one.