Cyclomune Eye Drop 0.1% (Cyclosporin 0.1%)

What is Cyclomune used for?

Cyclomune Eye Drops 0.1% are used to treat dry eye disease, which has not improved using tear substitutes, to increase natural tear production by the eye.  Tear production is reduced due to inflammation associated with a chronic eye disease called keratoconjunctivitis sicca, more commonly known as dry eye disease, in which the eye does not produce sufficient tears to cover the cornea and protect the surface of the eye.  This condition can be caused as a side effect of certain drugs, such as isotretinoin; as a symptom of certain diseases, such as rheumatoid arthritis; abnormal composition of tears causing them to evaporate rapidly; the aging process.  Often there is no known cause (idiopathic).  Chronic dry eyes results in severe keratitis, which is inflammation of the cornea, the transparent outermost surface at the front of the eye covering the pupil and iris.  Cyclomune Eye Drops 0.1% help prevent inflammation on the surface of the eye and this in turn helps increase natural tear production.  Cyclomune Eye Drops 0.1% can also be used in conjunction with artificial tears.

How does Cyclomune work?

Cyclomune Eye Drops 0.1% contain cyclosporine, which is an immunomodulator with immunosuppressant properties that has also been shown to have an anti-inflammatory effect.  Cyclosporine is usually taken orally for suppressing the immune system and preventing rejection of organ transplants or for treatment of certain autoimmune diseases.  When used for treating dry eye disease caused by reduced normal tear production, cyclosporine in Cyclomune Eye Drops 0.1% is thought to act as an immunomodulator by inhibiting the production of certain inflammatory chemicals called cytokines produced by lymphocytes at sites of inflammation.  By damping down the effect of inflammatory cytokines in the eye, cyclosporine in Cyclomune Eye Drops 0.1% reduces local inflammation and helps the eyes resume normal tear production, which is important to protect and lubricate the eyes.

What does Cyclomune contain?

Cyclomune Eye Drops 0.1% are an ophthalmic emulsion containing the active ingredient cyclosporine, an immunosuppressant and immunomodulator, used to increase tear production in dry eye disease.

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Treating dry eyes with Cyclomune

Cyclomune Eye Drops 0.1% contain cyclosporine, an immunomodulator that is used to increase natural tear production in dry eye disease.  Tear production is reduced due to inflammation associated with a chronic eye disease called keratoconjunctivitis sicca, more commonly known as dry eye disease, in which the eye does not produce sufficient tears to cover the cornea and protect the surface of the eye.  This condition can be caused as a side effect of certain drugs, such as isotretinoin; as a symptom of certain diseases, such as rheumatoid arthritis conditions; abnormal composition of teats causing them to evaporate rapidly; the aging process.  Often there is no known cause (idiopathic).  Chronic dry eyes results in inflammation which blocks normal tear production and causes damage to the structures of the eye surface.  Cyclosporine in Cyclomune Eye Drops 0.1% is thought to work by inhibiting the production of certain inflammatory chemicals called cytokines produced by lymphocytes at sites of inflammation.  Reducing inflammation locally helps the increase normal tear production, which is important to protect and lubricate the eyes.

What are the side effects of Cyclomune?

The most commonly reported side effects when using Cyclomune Eye Drops 0.1% include: burning sensation in the eye, eye redness and discharge, watery eyes, eye pain, foreign body sensation, itching, stinging, and blurred vision.

When should Cyclomune not be used?

You should not use Cyclomune Eye Drops 0.1% if you:

• are allergic to cyclosporine or any ingredients in Cyclomune
• are pregnant or are breastfeeding
• have an active eye infection

How should Cyclomune be used?

Before using your Cyclomune Eye Drops 0.1%, gently invert the vial a few times to ensure it is well mixed and the white emulsion is uniform and opaque.  Add one drop into each eye twice daily, 12 hours apart.  If you are also using artificial tears, you should wait for 15 minutes after applying your Cyclomune Eye Drops 0.1%.  Also remove contact lenses before use.  You should continue to use your Cyclomune Eye Drops 0.1% continually for as long as recommended by your doctor, usually for at least 30 days.

How long should you take Cyclomune?

You should continue to use your Cyclomune Eye Drops 0.1% continually for as long as recommended by your doctor, usually for at least 30 days.

Missed dose of Cyclomune

If you miss a dose of Cyclomune apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose.  Do not take a double dose.

How should Cyclomune be stored?

You should store your Cyclomune below 15-25°C in a cool dry place.