Potrate 10 Tablet (Potassium Citrate 1080mg)

INTRODUCTION

POTRATE 10MG TABLET contains Potassium citrate which belongs to the group of medicines known as Urinary alkalinizers. It is used in management of renal tubular acidosis (accumulation of acids due to decreased kidney functions) with calcium stones, uric acid lithiasis (uric acid stone formation) with or without calcium stones, hypocitraturic calcium oxalate nephrolithiasis (calcium oxalate stones) of any cause.

POTRATE 10MG TABLET is not recommended for use in patients with chronic kidney disease, heart disease such as heart failure or severe myocardial damage, uncontrolled diabetes mellitus, acute dehydration, adrenal insufficiency, delayed gastric emptying, extensive tissue breakdown, oesophageal compression, intestinal obstruction or narrowing, peptic ulcer disease, active urinary tract infection. Consult your doctor before taking it.

POTRATE 10MG TABLET should be used with caution in patients with heart block. Consult your doctor before taking it.

POTRATE 10MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Consult your doctor before taking it. POTRATE 10MG TABLET should be used in breast feeding women only if clearly necessary. Consult your doctor before taking it.

The safety and effectiveness of POTRATE 10MG TABLET in children have not been established. Consult your doctor before taking. Contact your doctor if the symptoms got worse.

USES OF POTRATE 10MG TABLET

Used to manage:

• Renal tubular acidosis (accumulation of acids due to decreased kidney functions) with calcium stones
• Hypocitraturic calcium oxalate nephrolithiasis (calcium oxalate stones) of any cause
• Uric acid lithiasis (uric acid stone formation) with or without calcium stones

HOW POTRATE 10MG TABLET WORKS

POTRATE 10MG TABLET works by increasing urinary PH (alkaline) and raises urinary citrate by stopping its clearance. It also increases the urinary potassium and also reduces urinary calcium levels in some patients. Thus the changes induced by POTRATE 10MG TABLET produces urine that is less prone to formation of stones (calcium oxalate, calcium phosphate and uric acid). POTRATE 10MG TABLET also decreases calcium ion concentration by forming complex and the rise in urinary pH also increases the ionization of uric acid to the more soluble urate ion.

DIRECTIONS FOR USE

Take POTRATE 10MG TABLET as advised by your doctor. Do not crush or chew the medicine while consuming it with water.

Your doctor will decide the correct dosage and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF POTRATE 10MG TABLET

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug- Drug interaction

Before taking POTRATE 10MG TABLET, inform your doctor if you are taking any of the following medicine:

• Aliskiren, potassium sparing diuretics (medicine used in the treatment of increased blood pressure, oedema, kidney disorders) such as spironolactone, eplerenone, amiloride
• Medicines used for high blood pressure (captopril, enalapril, lisinopril and angiotensin receptor blockers like losartan)
• Nonsteroidal anti-inflammatory drugs (used to treat pain such as indomethacin)
• Digoxin (medicine used for heart failure)
• Heparin (medicine used to prevent blood from clotting)
• Beta blockers (medicines used to decrease blood pressure) such as atenolol, metoprolol, propranolol
• Medicines that decrease gastrointestinal emptying time ex. anticholinergics such as dicyclomine (used for irritable bowel syndrome)

B. Drug- food interactions:

Avoid taking foods with high level of potassium such as almonds, apricots, bananas, beans, cantaloupe, carrot juice, figs, grapefruit, halibut, milk, oat bran, potato (with skin), tuna, salmon, spinach when consuming POTRATE 10MG TABLET.

Overdosage:

If you or anyone else accidentally takes too much of POTRATE 10MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are nausea, vomiting, diarrhoea, abdominal cramps, muscle paralysis, paraesthesia, lack of reflexes, fits, respiratory paralysis, ECG changes, hypotension and shock, bundle-branch block, ventricular arrhythmias, ventricular fibrillation, cardiovascular collapse or cardiac arrest.