Primacort 100 mg Inj (Hydrocortisone 100mcg)

INTRODUCTION

PRIMACORT 100MG contains Hydrocortisone sodium succinate which belongs to the group of medicine called corticosteroids. It is indicated in the treatment of swollen, painful joints and tendons in conditions such as, tennis elbow and golfer’s elbow. Hydrocortisone Injection can also be used to treat conditions such as severe asthma, allergic reactions, severe shock due to injury or infection or failure of the adrenal glands. It can also be used to treat shock following surgery, injuries, hypersensitivity (anaphylactic) reactions or other stressful conditions.

Corticosteroids are the substance that are naturally produced in your body and helps to maintain your health and well-being. Supplementing your body with extra corticosteroids in the form of injection/infusion can help to treat various illnesses and inflammatory conditions. PRIMACORT 100MG binds to the corticosteroid receptors of adrenal glands and mediates various physiological functions. It also blocks the production of various inflammatory mediators responsible for causing inflammation and allergies.

Do not reduce the dose or stop taking this medicine abruptly without informing your doctor. Your doctor will slowly reduce the dose to avoid withdrawal symptoms such as itching, fever, muscle/joint pain, runny nose, sticky eyes, sweating and weight loss. While taking this medicine, inform your doctor immediately if you experience any signs of mental problems such as depression or suicidal thoughts. Your doctor might reduce your dose or suggest an alternative therapy. Stay away from people having chickenpox, shingles or measles, because infections are easier to get and harder to spot while taking PRIMACORT 100MG.

The most common side effects of this medicine are injection site itching, pain and burning sensation. However, contact your doctor if you experience any other unusual side effects after taking this medicine. Do not take this medicine if you have any bacterial, viral or fungal infections. Before taking this medicine inform your doctor if you have any liver, kidney, heart or stomach problems. Pregnant and breastfeeding women should inform their doctor before taking PRIMACORT 100MG as a precaution.

USES OF PRIMACORT 100MG

Treats the following conditions:

Swollen, painful joints and tendons
Severe asthma
Allergic reactions
Severe shock due to injury or infection or failure of the adrenal glands. Shock following surgery, injuries, hypersensitivity (anaphylactic) reactions or other stressful conditions

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HOW PRIMACORT 100MG WORKS

PRIMACORT 100MG binds to the corticosteroid receptors of adrenal glands and mediates various physiological functions. It also blocks the production of various inflammatory mediators responsible for causing inflammation and allergies.

DIRECTIONS FOR USE

PRIMACORT 100MG will be given to you only by a doctor or nurse into the vein (intravenously) or muscle (intramuscularly) as an injection/infusion. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF PRIMACORT 100MG

SERIOUS
Allergic reactions (such as skin rash, swelling of the face and difficulty in breathing)
Symptoms of acute pancreatitis (stomach pain spreading through your back, with vomiting, shock and loss of consciousness)
Symptoms of bleeding ulcers (severe stomach pain, back pain, bleeding from the anus, black or bloodstained stools and vomiting up of blood)
Fever or flu-like symptoms
Pulmonary embolus (blood clot in the lung), chest pain, breathlessness and coughing up blood
Symptoms of pseudo tumour cerebri in children (increased cranial pressure, headaches with vomiting, lack of energy and drowsiness)
Thrombophlebitis (blood clots in the veins with redness and swelling)
COMMON
Injection site itching, pain or irritation
High blood pressure, palpitations
Muscle cramps or spasms
Nausea, vomiting, indigestion, bloating, hiccups
Blurred vision, glaucoma, eye inflammation
Central serous chorioretinopathy (visual impairment leading to retinal detachment)
Permanent slowing of growth in children
Bone fractures
Mental problems (such as depression, suicidal thoughts, mania, anxiety, confusion, difficulty in sleeping, loss of memory, or hallucinations)
Infections

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Bloating:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor immediately.

WARNING & PRECAUTIONS

PREGNANCY
PRIMACORT 100MG should be used with caution in pregnant women. Your doctor will decide whether you should use this medicine or not.

BREASTFEEDING
PRIMACORT 100MG should be used with caution in breastfeeding women. Consult your doctor before taking this medicine.

ALCOHOL
Do not drive or operate any tools or machines if your ability is affected by this medicine.

KIDNEY
PRIMACORT 100MG should be taken with caution in patients with kidney disease. Consult your doctor for advice.

LIVER
PRIMACORT 100MG should be taken with caution in patients with liver disease. Consult your doctor for advice.

ALLERGY
Do not take this medicine if you are allergic (hypersensitive) to hydrocortisone or any other corticosteroid medicine.

HEART DISEASE
PRIMACORT 100MG should be taken with caution in patients suffering from congestive heart disease, a recent heart attack, high blood pressure or other heart problems. Consult your doctor for advice.

OTHERS

Before taking PRIMACORT 100MG, inform your doctor if you have following conditions:

Stroke or traumatic brain injury
Chicken pox or shingles (viral infections)
Ocular herpes simplex (viral eye infection)
Severe depression or bipolar disorder
Epilepsy
Diabetes
Glaucoma (increased pressure in the eyes)
Muscle weakness following steroidal administration in the past
Myasthenia gravis (muscle weakness)
Hypothyroidism (decreased thyroid levels)
Kaposi’s sarcoma (a type of cancer that causes purplish lesions on the skin)
Osteoporosis (thinning of bones)
Pheochromocytoma (a rare tumor in the tissues of adrenal glands)
Amoebic dysentery or and strongyloidiasis (an infestation of gut worm)
Tuberculosis in the past
Stomach ulcers or other intestinal problems
Thrombophlebitis (blood clot in veins with redness and swelling)
Tuberculosis in the past
Got vaccinated recently or going to receive any vaccinations
Going to have any surgery

INTERACTIONS

Talk to your doctor, if you are taking:

Acetazolamide (used to treat epilepsy and glaucoma)
Aminoglutethimide (used to treat cancer)
Anticoagulants (used for blood thinning) e.g. acenocoumarol, phenindione and warfarin
Anticholinesterases (used to treat myasthenia gravis) e.g. distigmine and neostigmine
Antibiotics (used to treat bacterial infection) e.g. erythromycin
Non-steroidal anti-inflammatory medicines (e.g. aspirin and ibuprofen)
Medicines used to treat epilepsy (e.g. phenytoin, phenobarbital, carbamazepine and primidone)
Medicines used to treat heartburn and acid indigestion (e.g. carbenoxolone and cimetidine)
Ciclosporin (used to treat psoriasis or prevent graft rejection)
Digoxin (used to treat arrhythmia or heart failure)
Mibefradil and diltiazem (used to treat high blood pressure and other heart problems)
Diuretics (used to increase urine output) e.g. furosemide
Itraconazole or ketoconazole (used to treat fungal infections)
Pancuronium (a neuromuscular blocking agent used in some surgical procedures)
Rifabutin and rifampicin (used to treat tuberculosis)
Live vaccines