Premarin 0.3mg Tablet (Conjugated Estrogens 0.3mg)

Premarin 0.3mg Tablet

PREMARIN 0.3MG contains Conjugated estrogens which belongs to the group of medicines called Hormone Replacement Therapy. It is used among postmenopausal women to relieve menopausal symptoms such as hot flushes, sleep problems, irritability, and depression.

It can also be used to prevent osteoporosis (bone loss and fragility) among postmenopausal women who are at risk of developing fractures easily. PREMARIN 0.3MG should be used only in women who do not have their period at least for the past 6 months.

Conjugated estrogen is a synthetic derivative of a female sex hormones called estrogen. It supplements our body with sufficient levels of estrogens which usually becomes deficient during menopause. As a result, it provides relief from postmenopausal symptoms such as hot flushes, sleep problems, irritability, depression, and bone loss.

PREMARIN 0.3MG is not a contraceptive (birth control pill), therefore it cannot prevent you from becoming pregnant. Women who are in pre-menopause (less than 6 months from last periods) or aged below 50 years must use a suitable contraceptive method to prevent pregnancy.

During treatment with PREMARIN 0.3MG, your doctor will instruct you to have periodic blood tests and regular physical examination (breast examination) to avoid the risk of unwanted side effects. Avoid drinking grapefruit juice while taking PREMARIN 0.3MG as it may interfere with the effects of PREMARIN 0.3MG.

Do not take PREMARIN 0.3MG if you have or previously had breast cancer, uterine cancer, unexplained vaginal bleeding, heart problems or blood clots. Before taking PREMARIN 0.3MG inform your doctor if you have any liver or kidney problems, diabetes, migraine headache, asthma, or epilepsy.

PREMARIN 0.3MG is not intended for use in pregnant and breastfeeding women. The most common side effects of taking PREMARIN 0.3MG are stomach pain, headache, vaginal infection, or vaginal discharge, weight gain, memory loss and changes in libido. Consult your doctor if any of these side effect worsens.

Also, inform your doctor if you experience any changes in your breast such as breast pain, tenderness, discharge from the nipple, or lump growth in the breasts, heavy menstrual bleeding, pain, swelling, redness of the legs, sudden chest pain or difficulty in breathing.

USES OF PREMARIN 0.3MG

It is used in postmenopausal women to:

• Relieve menopausal symptoms
• Prevent osteoporosis

HOW PREMARIN 0.3MG WORKS

PREMARIN 0.3MG supplements our body with sufficient levels of female sex hormones (estrogen). This helps in treating problems associated with hormonal deficiency states such as menopause. As a result, it provides relief from postmenopausal symptoms such as hot flushes, sleep problems, irritability, depression, and bone loss.

DIRECTIONS FOR USE

Take PREMARIN 0.3MG strictly as advised by your physician. Swallow PREMARIN 0.3MG with a glass of water. Do not crush or chew the medicine. Try to take PREMARIN 0.3MG at the same time each day.

Do not miss any dose of PREMARIN 0.3MG in between the therapy, as it may reduce its effectiveness. In case if you have missed a dose of PREMARIN 0.3MG take it as soon as you remember. Avoid taking a double dose of PREMARIN 0.3MG to compensate the missed dose it may lead to bleeding or spotting. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition.

SIDE EFFECTS OF PREMARIN 0.3MG

HOW TO MANAGE SIDE EFFECTS

Nausea and Vomiting:

Take PREMARIN 0.3MG with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interaction:

Before taking PREMARIN 0.3MG, inform your doctor, if you are taking any of the following:

• Medicines used to treat epilepsy (Ex. phenobarbital, phenytoin, carbamazepine)
• Medicines used to treat tuberculosis (Ex. rifampicin, rifabutin)
• Medicine used to treat HIV infection (Ex. nevirapine, efavirenz, ritonavir and nelfinavir)
• Medicines used to treat bacterial infections (Ex. erythromycin, clarithromycin)
• Medicines used to treat fungal infections (Ex. ketoconazole, itraconazole)
• St. john’s wort (an herbal medication used to treat depression)
• Metyrapone (a medicine used to adrenal insufficiency)
• Cimetidine (a medicine used to treat stomach ulcers)
• Dexamethasone (a corticosteroid used to treat inflammation)

B. Drug-Food Interaction:

Avoid drinking grapefruit juice while taking PREMARIN 0.3MG as it may alter the effects of this medicine.

Overdosage:

If you or anyone else accidentally took more PREMARIN 0.3MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, breast tenderness, dizziness, stomach pain, drowsiness, weakness, and short periods of vaginal bleeding.