Progynova 1mg Tablet (Estradiol 1mg)

Description

Progynova 1 MG Tablet is a form of female sex hormone, estrogen. It is used to relieve symptoms occurring after menopause such as vaginal dryness/burning/itching, hot flashes, etc. and prevents osteoporosis (a condition in which bone becomes weak and fragile).

Progynova 1 MG Tablet shows side effects like stomach pain, headache, changes in weight, oedema (swelling) of legs, breast tenderness, mood alterations including anxiety and depressed mood. Inform your doctor if these side effects become severe or persist for a long time.

Progynova 1 MG Tablet can be taken with or without food. Take it at the same time every day for the ease of remembering. Your doctor will decide the dosage of this medicine based on the indication you are taking it for.

Progynova 1 MG Tablet is not recommended for use if you have abnormal/unusual vaginal bleeding. Inform your doctor if you have any kidney problems, diabetes, or any other medical conditions. Do not take this medicine if you are pregnant or planning a pregnancy. Inform your doctor if you are breastfeeding to understand its benefits and the risk to your infant.

Substitutes

List of substitutes for Progynova 1 MG Tablet
Estova 1 MG Tablet
Cipla Ltd.
Estrabet 1 MG Tablet
Abbott India Ltd.
Evatone 1 MG Tablet
Serum Institute Of India Ltd.
Myestra 1 MG Tablet
Mylan Pharmaceuticals

Side effects

Major & minor side effects for Progynova 1 MG Tablet
Breast pain and tenderness
Vomiting
Weight gain
Dizziness
Depression
Back pain
Headache
Vaginal discharge with no odor
Swelling of face, lips, eyelids, tongue, hands and feet
Discharge from the nipple
Change in the texture of breast skin and nipples

Uses of Progynova 1 MG Tablet

What is it prescribed for?
Post menopausal symptoms
A post-menopausal symptom is a group of symptoms that you experience after menopause (end of menstrual cycles). These symptoms may include vaginal dryness/itching, hot flushes, irritability, and mood swings. Progynova 1 MG Tablet works by balancing the level of hormones (chemical messengers) that cause these symptoms in your body.
Postmenopausal osteoporosis
Postmenopausal osteoporosis is a condition that causes weak and fragile bones due to decreased levels of estrogen in your body. Its symptoms are back pain, change in posture, etc. Progynova 1 MG Tablet is used to prevent and treat the symptoms of osteoporosis in women who have reached menopause.
Hormonal replacement therapy
Progynova 1 MG Tablet is used as Hormonal replacement therapy to relieve symptoms associated with menopause. This includes mood swings, hot flushes, decreased urge to have sex and vaginal dryness. You are advised to use this medicine only upon your doctor’s advice.

Related Products

List of related products
Progynova 2 MG Tablet

When not to use?

Allergy
Avoid taking Progynova 1 MG Tablet if you are allergic to it. Allergic reactions are rare; however, contact your doctor immediately if you experience symptoms like rashes, itching/swelling (particularly of your face/tongue/throat), severe dizziness, and breathing difficulty, etc.
Undiagnosed vaginal bleeding
Progynova 1 MG Tablet is not recommended for use if you have an abnormal vaginal bleeding episode that has not been diagnosed by your doctor. If you have any menstrual abnormalities, consult your doctor first before taking this medicine.
Heart and blood vessel disorder
Progynova 1 MG Tablet is not recommended if you have an active or history of stroke (brain damage due to blocked blood flow) or heart attack. This medicine should also be avoided if you have an active or previous blood clotting issue. Progynova 1 MG Tablet can lead to an increase in clot formation if taken in higher doses and thus can worsen your condition.
Estrogen-dependent tumor
Progynova 1 MG Tablet is not recommended if you have cancer that is sensitive to oestrogens, such as breast and cancer of the endometrium (womb lining), or if you are suspected of having it.
Liver Tumours
Liver tumours are types of cancer that form in the liver. Progynova 1 MG Tablet is not recommended in liver tumours because long term use of this medicine may worsen your condition.
Porphyria
Porphyria is a disorder resulting from the accumulation of certain chemicals related to blood cell proteins. Progynova 1 MG Tablet is not recommended in the presence of porphyria.

Warnings

Warnings for special population
Pregnancy
Progynova 1 MG Tablet is not recommended if you are pregnant or planning a pregnancy. Contact your doctor if you suspect pregnancy while being treated with this medicine.
Breast-feeding
Progynova 1 MG Tablet may not be safe if you are breastfeeding women. Consult your doctor before taking this medicine.
General warnings
Dementia
Dementia means loss of memory, thinking and social abilities. Progynova 1 MG Tablet has been associated with an increased risk of dementia especially in the elderly. It is advised to be taken with caution if used for longer durations.
Breast cancer
Progynova 1 MG Tablet increases the risks of breast cancer, hence should be used at the lowest doses and the duration of treatment should be kept as low as possible.
Jaundice like symptoms
Progynova 1 MG Tablet may cause yellowing of the eyes and skin due to its effect on the liver and the gall bladder. Inform your doctor if you experience any symptoms of jaundice.
Surgery
You should stop taking Progynova 1 MG Tablet at least 4 weeks before a planned surgery as it may interfere in bleeding control.
Vision abnormalities
Progynova 1 MG Tablet may cause blurring of vision and other effects on your eye like proptosis (bulging of the eye), diplopia (double vision), etc. Inform your doctor if you experience any side effects like blurred vision, excessive drying of the eyes. Do not perform activities such as driving vehicles or operating machines if you experience any of these symptoms.
Gallbladder disease
Progynova 1 MG Tablet can increase the risk of gallstones ( small, hard stones that develop due to the accumulation of digestive fluids (bile) in your gallbladder), especially in postmenopausal women. Use it with caution if you have a pre-existing gall bladder problem.
Formation of blood clots
Progynova 1 MG Tablet has been associated with the formation of blood clots especially during the first year of taking it and in elderly people.
Use in children
Progynova 1 MG Tablet is not recommended for use in children and adolescents below 18 years of age because the safety and efficacy of use are not clinically established.

Dosage

Missed Dose
Do not miss a dose of Progynova 1 MG Tablet. In case you forget to take your medicine, take the missed dose as soon as you remember. If your next dose is near, skip the missed dose. Do not double your dose to compensate for a missed one.
Overdose
Seek emergency medical treatment in case of an overdose of Progynova 1 MG Tablet. Symptoms of an overdose may include nausea, vomiting, vaginal bleeding etc.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Carbamazepine
Dexamethasone
Prednisolone
Tranexamic Acid
Warfarin
Disease interactions
Hypertension
Hypertension is a condition in which your blood pressure level is higher than normal. Use Progynova 1 MG Tablet with caution if you have hypertension because it may increase the risk of heart attack and strokes (brain damage due to blocked blood flow).
Diabetes
Diabetes is a condition in which there are high blood sugar levels. Progynova 1 MG Tablet should be used with caution in the presence of diabetes.
Asthma
Asthma is a condition where the airways of your lungs are constricted. Use Progynova 1 MG Tablet with caution if you are having asthma.
Food interactions
Avoid or limit the consumption of grapefruit juice while you are on treatment with Progynova 1 MG Tablet. Grapefruit juice may interfere with the effectiveness of the medicine and may cause some side effects.
Lab interactions
Thyroid function test
Inform your doctor about Progynova 1 MG Tablet before thyroid function test as it may interfere with the test results.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Progynova 1 MG Tablet as instructed by your doctor.
Do not take this medicine in larger or smaller quantities or for longer durations than recommended.
It is advised to do regular follow-ups with your doctor while taking this medicine.
If you have any unusual vaginal bleeding or spotting, abnormal vaginal discharge, or vaginal pain while using Progynova 1 MG Tablet, inform your doctor.
If you experience unexplained swelling and discomfort in your limbs, shortness of breath, chest pain, or changes in your eyesight, stop taking this medication and contact your doctor immediately.
These symptoms might be the result of a blood clot in a vein.