Maxpride 100 Tablet (Amisulpride 100mg)

 MAXPRIDE 100 MG TABLET

MAXPRIDE 100 MG TABLET belongs to a group of medicines called ‘antipsychotics‘ primarily used to treat long term (chronic) schizophrenia and postoperative nausea/vomiting. Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). In schizophrenic disorders, there are positive symptoms (like delusions, hallucinations and thought disorders) along with negative symptoms (like blunted effect, emotional and social withdrawal). Nausea is an uneasy feeling in which the person feels an urge to vomit, whereas vomiting is an uncontrollable reflex that expels the stomach’s contents through the mouth.

MAXPRIDE 100MG TABLET contains Amisulpride, which helps restore the balance of certain natural substances in the brain. The key action of MAXPRIDE 100MG TABLET is to block some of the dopamine receptors in the brain and correct dopamine’s overactivity. On the other hand, it also affects other brain neurotransmitters such as serotonin (5-HT), which may also lead to its beneficial effects. MAXPRIDE 100MG TABLET also stops the sensation of vomiting/nausea by blocking the D2 receptors located in the chemoreceptor trigger zone – CTZ of the brain responsible for inducing vomiting.

Take MAXPRIDE 100MG TABLET as prescribed by your doctor. You are advised to take MAXPRIDE 100MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience dryness in the mouth, constipation, weight gain, decreased blood pressure, dystonia (involuntary muscle contractions), akathisia (inability to stay still), parkinsonism, increased prolactin level in blood. Most of these side effects of MAXPRIDE 100MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to MAXPRIDE 100MG TABLET or any other medicines, please tell your doctor. MAXPRIDE 100MG TABLET is not recommended for children below 18 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking MAXPRIDE 100MG TABLET. Use MAXPRIDE 100MG TABLET with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects.  If you have breast cancer, pheochromocytoma (tumour of the adrenal gland), pituitary gland prolactinoma (tumour of the pituitary gland), fits, Parkinson’s disease, kidney or heart problems, inform your doctor before taking MAXPRIDE 100MG TABLET. Drive only if you are alert after taking MAXPRIDE 100MG TABLET as it may cause drowsiness or dizziness.

Uses of MAXPRIDE 100MG TABLET

Postoperative nausea and vomiting (PONV), Schizophrenia

Medicinal Benefits

MAXPRIDE 100MG TABLET contains Amisulpride, a group of medicines called antipsychotics used to treat a mental illness called schizophrenia, dysthymia (long-term depression), and bipolar disorder. Additionally, MAXPRIDE 100MG TABLET has anti-emetics properties used either monotherapy or in combination with other antiemetic drugs to prevent nausea and vomiting, which might occur after surgery. The key action of MAXPRIDE 100MG TABLET is to block some of the brain’s dopamine receptors and correct dopamine’s overactivity, thereby producing a calming effect in the brain. Altogether, MAXPRIDE 100MG TABLET may help decrease hallucinations and help you think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. MAXPRIDE 100MG TABLET is more effective than other antipsychotic drugs such as olanzapine, haloperidol, quetiapine, and clozapine to treat schizophrenic symptoms.

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Directions for Use

MAXPRIDE 100MG TABLET is available in tablet, oral solution and injection forms.Tablet: Take MAXPRIDE 100MG TABLET as prescribed by your doctor. The doctor determines the dose and duration of the medicine. Swallow the medicines as a whole with a glass of water. Do not crush, chew, or break it. Oral solution: The liquid form of MAXPRIDE 100MG TABLET should be taken by mouth using the measuring cup provided by the pack; shake the bottle well before each use.Injection: A healthcare professional will administer the injection form of MAXPRIDE 100MG TABLET; do not self-administer. Depending on your medical condition, your doctor will decide how long you need to take MAXPRIDE 100MG TABLET.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MAXPRIDE 100MG TABLET

• Dizziness
• Drowsiness
• Lightheadedness
• Dry mouth
• Constipation
• Weight gain
• Decreased blood pressure
• Dystonia (involuntary muscle contractions)
• Akathisia (inability to stay still)
• Parkinsonism
• Increased prolactin level in the blood
• Low potassium level

In-Depth Precautions and Warning

Drug Warnings

Do not take MAXPRIDE 100MG TABLET if you are allergic (hypersensitive) to olanzapine or any other ingredients present in this medicine or have a medical history of prolactin dependent tumour or breast cancer, phaeochromocytoma (a tumour on the adrenal gland), pituitary tumour. MAXPRIDE 100MG TABLET should not be given to children as safety have not been established. Use MAXPRIDE 100MG TABLET with extreme caution in elderly patients above 65 years of age as there is an increased risk of severe adverse effects. If you are pregnant or breastfeeding, please consult a doctor before taking MAXPRIDE 100MG TABLET. MAXPRIDE 100MG TABLET may impair fertility, so inform your doctor if you are planning for pregnancy. Inform your doctor if you are previously diagnosed with kidney disease, liver disease epilepsy or seizures (fits), Parkinson’s disease, unusual heart rate (rhythm), slow heartbeat (less than 55 beats per minute), low potassium levels in your blood, prolonged QT interval (heart conduction problem), if you or someone else in your family has a history of blood clots, heart problems, stroke, diabetes, have a low number of white blood cells (agranulocytosis), leucopenia (blood disorder). MAXPRIDE 100MG TABLET may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with MAXPRIDE 100MG TABLET as it could lead to increased drowsiness and dizziness.

Drug Interactions

Drug-Drug Interaction: MAXPRIDE 100MG TABLET may have interaction with medicines used to reduce heart rate (quinidine, disopyramide, amiodarone, sotalol) medicines for high blood pressure and heart problems (diltiazem, verapamil, guanfacine, digitalis, clonidine, bepridil) pain killers (morphine, pethidine, tramadol, indomethacin, aspirin, acetaminophen, hydrocodone) antimalarial (mefloquine), anti-histamines (promethazine, diphenhydramine)  medicine used to treat schizophrenia (clozapine) neuroleptics (pimozide, haloperidol, imipramine, duloxetine, citalopram, sertraline, fluoxetine, paroxetine), anti-anxiety drugs (lorazepam and diazepam), antipsychotics (flupentixol, droperidol, haloperidol, fluphenazine, pipamperone), antibiotics (ciprofloxacin, erythromycin, sparfloxacin, moxifloxacin), antiparkinson (levodopa, ropinirole, bromocriptine).

Drug- Food Interaction: MAXPRIDE 100MG TABLET may interact with grapefruit juice and alcohol. Therefore, avoid intake of grapefruit juice and alcohol with MAXPRIDE 100MG TABLET as it may increase the risk of adverse effects.

Drug-Disease Interaction: If you have breast cancer, pheochromocytoma (tumour of the adrenal gland), pituitary gland prolactinoma (tumour of the pituitary gland), fits, Parkinson’s disease, kidney or heart problems, inform your doctor before taking MAXPRIDE 100MG TABLET.