Dabipla 150mg Capsule (Dabigatran Etexilate 150mg)

INTRODUCTION

DABIPLA 150MG contain dabigatran etexilate which belongs to a group of medicine called anticoagulants. It is used to prevent the formation of blood clots in the veins after knee or hip replacement surgery. If you have a form of irregular heart rhythm called nonvalvular atrial fibrillation this medicine helps in preventing the formation of blood clots in the brain (stroke) and other blood vessels in the body. It also used to treat blood clots formed in the veins of your legs and lungs and prevent it from reoccurring.

Blood clot is a clump of bloods that has changed from liquid to gel-like or semisolid state. Clotting is a process which prevents the loss of too much bloods in certain instance. By making change in your lifestyle such as not smoking, eating a healthy diet, getting regular exercise, and losing weight can reduce your risk of having a blood clot.

Do not take this medicine if you have severe kidney, liver, heart problems, if you have any bleeding disorders or if you are taking other medicines to reduce blood clotting. Pregnant and breastfeeding women should consult their doctor before taking this medicine. This medicine is strictly not recommended for use in children and adolescents below 18 years old.

USES OF DABIPLA 150MG

Prevent and treat blood clots

HOW DABIPLA 150MG WORKS

DABIPLA 150MG is a direct thrombin inhibitor which works by reversibly blocking the catalytic site of thrombin and produces a rapid (within 2 hours) anticoagulant action.

DIRECTIONS FOR USE

Always take DABIPLA 150MG exactly as your doctor has told you. This medicine must be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine. Your doctor will decide the suitable dose depending on your conditions.

SIDE EFFECTS OF DABIPLA 150MG

SERIOUS
Bruising or bleeding
Allergic reaction (including hives, rash, and itching)
Serious allergic reaction (including chest pain or chest tightness, swelling of your face or tongue, trouble breathing or wheezing, dizziness, or faint)
COMMON
A fall in the amount of haemoglobin in blood
Unusual laboratory test results on liver function
Bleeding may happen from the nose, into the stomach or bowel, from penis/vagina or urinary tract (including blood in the urine that stains the urine pink or red) or under the skin
Stomach pain, stomach upset or burning
Indigestion
Frequent loose or liquid bowel movements
Nausea
RARE
Blood-stained discharge from the site of entry of a catheter into a vein
Coughing of blood or blood-stained sputum
Fall in the number of platelets in the blood
Ulcer in the stomach or bowel (incl. ulcer in the gullet)
Inflammation of the gullet and stomach
Reflux of gastric juice into the gullet
Difficulty in swallowing
Fluid exiting a wound
Liver enzymes increased
Yellowing of the skins or whites of the eyes

HOW TO MANAGE SIDE EFFECTS

Stomach pain:

Keep try to rest and relax. Eat and drink slowly and smaller and frequent meals. Applying a heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.

Indigestion:

Drink water. Avoid lying down. Take warm bath or use heat bag. Avoid smoking and drinking alcohol. Avoid difficult-to-digest foods.

Nausea:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

INTERACTIONS

Talk to your doctor if you are taking,

Warfarin, phenprocoumon, acenocoumarol, heparin, clopidogrel, prasugrel, ticagrelor, rivaroxaban, acetylsalicylic acid (used to reduce blood clot)
Ketoconazole, itraconazole (used to treat fungal infection)
Amiodarone, dronedarone, quinidine, verapamil (used to treat abnormal heart beats)
Tacrolimus, cyclosporine (prevent organ rejection after transplantation)
Glecaprevir and pibrentasvir (used to treats hepatitis C)
Acetylsalicylic acid, ibuprofen, diclofenac (used to treat pain and inflammation)
St. John’s wort, selective serotonin re-uptake inhibitors or serotonin norepinephrine re-uptake inhibitors (used to treat depression)
Rifampicin or clarithromycin (used to treat infection)
Ritonavir (used to treat HIV infection)
Carbamazepine, phenytoin (used to treat epilepsy)