Zanocin DS Tablet (Ofloxacin 400mg)

INTRODUCTION

ZANOCIN DS contains Ofloxacin which belongs to a group of medicines called quinolone antibiotics. It is used to treat conditions such as respiratory tract, urinary tract, gynaecological and skin soft tissue infections. Ofloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase.

Ofloxacin is in a class of antibiotics called fluoroquinolones which works against bacteria that cause infections and stops the growth of the bacteria causing the infection and clears the infection.

Before taking ZANOCIN DS inform your doctor if you have any allergic reactions, liver, kidney or heart problems. Inform your physician if you are pregnant or breastfeeding. It is not suitable for children and adolescents below 18 years of age. The common side effects are nausea, stomach pain, diarrhoea or headache.

USES OF ZANOCIN DS

Treats respiratory tract, urinary tract, gynaecological and skin soft tissue infections (bacterial infections)

HOW ZANOCIN DS WORKS

ZANOCIN DS works against bacteria that cause infections and stops the growth of the bacterial enzyme called DNA-gyrase thus prevents the bacterial cells from dividing and repairing them.

DIRECTIONS FOR USE

Always take ZANOCIN DS as instructed by your doctor. Swallow as whole and do not crush or chew. Do not exceed the recommended dose.

SIDE EFFECTS OF ZANOCIN DS

SERIOUS
Blurred, double or altered colour vision
COMMON
Nausea
Stomach pain
Diarrhoea
Headache
RARE
Difficulty breathing, swelling of the face, lips and throat
Skin rashes
Inflammation of the bowel
Numbness or tingling in the hands and feet

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HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink plenty of fluids and ORS can be used to prevent dehydration.

Nausea:

Drink clear or ice-cold drinks, eat bland foods and avoid fried or sweet foods.

Stomach pain:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

Headache:

Rest and drink plenty of fluids. Apply a wet or cold cloth to forehead and rest in a quiet, comfortable, dark room.

WARNING & PRECAUTIONS

PREGNANCY
There are limited studies available on ZANOCIN DS and it may cause harmful effects on the developing baby. Consult your doctor.

BREASTFEEDING
There are limited human data suggests that the ZANOCIN DS may pass into the breastmilk and harm the baby. Consult your doctor.

DRIVING AND USING MACHINES
Do not drive or handle any machines if you experience sleepy, dizzy or eyesight problems. Consult your doctor for advice.

ALCOHOL
Consumption of alcohol is not recommended while taking this ZANOCIN DS.

KIDNEY
ZANOCIN DS should be used with caution in patients with kidney disease, if needed dose will be adjusted accordingly. Consult your doctor for advice.

LIVER
ZANOCIN DS should be used with caution in patients with liver disease, if needed dose will be adjusted accordingly. Consult your doctor for advice.

ALLERGY
Tell your doctor if you are allergic (hypersensitive) to Ofloxacin.

HEART DISEASE
ZANOCIN DS should be used with caution in patients with irregular heartbeat, heart failure or any other heart conditions. Consult your doctor for advice.

OTHERS

Inform your doctor before taking this medicine, if you have or had,

Allergic reactions
Epilepsy
History of inflammation and swelling of the tendons (tendonitis)
Inherited disorder that affects the red blood cells
Aortic aneurysm
Mental illness
Salt imbalance in the blood
Myasthenia gravis
Diabetes

INTERACTIONS

Tell your doctor if you are taking,

Ciprofloxacin, nadifloxacin, norfloxacin (treats infection)
Quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide (treats heart problems)
Clomipramine, amitriptyline (used to treat depression)
Erythromycin, clarithromycin, azithromycin
Medicines or dietary supplements that contain iron (for anaemia) or zinc
Sucralfate (used for stomach ulcers)
Antacids, cimetidine
Corticosteroids, used for treatment of inflammation and swelling
Ibuprofen or diclofenac and theophylline
Glibenclamide (treats diabetes)
Probenecid (used for gout)
Methotrexate (used for rheumatism)
Warfarin (treats blood clot)
Didanosine (used to treat HIV infections)
Furosemide