Vymada 100mg Tablet (Sacubitril 49mg / Valsartan 51mg)
$84.00 – $235.00
Country of Origin | India |
---|---|
Dosage Form | Tablets |
Equivalent Brand | Entresto |
Generic Name | Sacubitril / Valsartan |
Indication | Heart failure |
Manufacturer | Novartis India Ltd |
Packaging | 28 tablets in 1 strip |
Composition | Sacubitril (49mg) + Valsartan (51mg) |
Pack Size | 28 Tablet/s, 56 Tablet/s, 84 Tablet/s |
Vymada 100mg Tablet (Sacubitril 49mg / Valsartan 51mg) | |||
Pack Size | Price | Price/Unit | Add To Cart |
28 Tablet/s | $84.00 (3/unit) | $3 | |
56 Tablet/s | $160.00 (2.86/unit) | $2.86 | |
84 Tablet/s | $235.00 (2.8/unit) | $2.8 |
INTRODUCTION
VYMADA 100MG is a combination of Sacubitril and Valsartan which belongs to a group of medicines called Angiotensin receptor neprilysin inhibitors. VYMADA 100MG is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (New York Heart Association Class II-IV) and reduced ejection fraction. Heart failure occurs when the heart is weak and cannot pump enough blood to the lungs and to the rest of the body and it is characterized by symptoms such as breathlessness, fatigue, tiredness, and ankle swelling.
Sacubitril is a neprilysin inhibitors which works by relaxing and widening the blood vessels and makes it easier for the heart to pump blood throughout the body. Valsartan is an angiotensin-II receptor blocker works by relaxing the blood vessels by blocking a substance called angiotensin-II (causing blood vessels to tighten) which is produced in the body and thus lowers the blood pressure.
Before taking VYMADA 100MG inform your doctor if you have liver, kidney, or heart problems. VYMADA 100MG is not recommended for use in pregnant and breast-feeding women. It is not suitable for use in children and adolescents under 18 years of age and it should be used with caution in elderly patients (65 years of age and above). Before taking VYMADA 100MG inform your doctor about previous allergy and medication history to prevent serious effect. The most common side effects of taking VYMADA 100MG are dizziness, cough headache, tiredness, nausea, and weakness. Contact your doctor if any of the symptoms worsen.
USES OF VYMADA 100MG
- Treats long-term heart failure in adults
HOW VYMADA 100MG WORKS
VYMADA 100MG helps to treat long-term heart failure, where sacubitril works by relaxing and widening the blood vessels and makes it easier for the heart to pump blood throughout the body and valsartan works by relaxing the blood vessels by blocking a substance called angiotensin-II (causing blood vessels to tighten) which is produced in the body and thus lowers the blood pressure.
DIRECTIONS FOR USE
Take VYMADA 100MG as advised by your physician. Swallow VYMADA 100MG with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF VYMADA 100MG
COMMON
- Dizziness, light-headedness (low blood pressure)
- Signs of high levels of potassium in the blood (irregular heartbeat, muscle weakness)
- Decrease in renal function
- Cough
- Diarrhoea
- Signs of low red blood cells (anemia)
- Tiredness
- Headache
- Fainting or spinning sensation
- Weakness
- Nausea
- Inflammation of lining of the stomach (stomach pain, nausea)
- Signs of low sugar levels in the blood (fast heartbeat, sweating, nervousness, or anxiety)
UNCOMMON
- Allergic reaction with rash and itching
- Dizziness when switching from sitting to standing position
RARE
- Hallucinations
- Changes in sleeping pattern
Stop taking VYMADA 100MG and contact your doctor immediately if you experience any of the following side effects:
- Severe allergic reactions (swelling of the face, lips, tongue, or throat, which may cause difficulties in breathing or swallowing (angioedema))
HOW TO MANAGE SIDE EFFECTS
Tiredness:
Drink plenty of fluids and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if your symptom did not improve.
Nausea:
Stick to simple meals. Avoid eating oily, fried, and spicy foods. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom did not improve.
Diarrhoea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
VYMADA 100MG is not recommended for use in early pregnancy and must not be used in pregnant women when more than 3 months pregnant, as it may cause serious harm to the baby. Consult your doctor before taking VYMADA 100MG if you think you may be pregnant.
BREASTFEEDING
VYMADA 100MG is not recommended for use in breastfeeding women. Consult your doctor before taking VYMADA 100MG if you are breast-feeding or about to start breast-feeding.
DRIVING AND USING MACHINES
Avoid driving or handle any machines while taking VYMADA 100MG because it may cause dizziness or tiredness.
KIDNEY
VYMADA 100MG should be used with caution in patients with severe kidney disease and with narrowed kidney artery. Consult your doctor before taking VYMADA 100MG.
LIVER
VYMADA 100MG is not recommended in patients with severe liver disease and it should be used with caution in patients with liver disease. Consult your doctor before taking VYMADA 100MG.
ALLERGY
Do not take VYMADA 100MG if you are allergic (hypersensitive) to Sacubitril and Valsartan.
OTHERS
VYMADA 100MG is not recommended for use, if you have:
- Diabetes or impaired kidney function (and being treated with aliskiren (blood pressure lowering medicine))
- Personal or family history of angioedema (when taking angiotensin receptor blockers (ARB) such as valsartan, telmisartan)
Before taking VYMADA 100MG inform your doctor if you have:
- History of angioedema
- Low blood pressure
- Vomiting or diarrhea
- Dehydration
- Hallucinations, paranoia, or changes in sleeping pattern
Use in pediatrics:
VYMADA 100MG is generally not recommended for use in children and adolescents (under 18 years of age). Consult child’s doctor for advice.
Use in geriatrics:
VYMADA 100MG should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking VYMADA 100MG.
INTERACTIONS
A. Drug-Drug interactions:
Before taking VYMADA 100MG inform to your doctor, if you are taking any of these medicines:
- Enalapril, lisinopril or ramipril (treats high blood pressure)
- Aliskiren and angiotensin receptor blockers such as telmisartan, losartan (treats heart failure)
- Atorvastatin (lowers high cholesterol levels)
- Sildenafil (treats erectile dysfunction or lung hypertension)
- Potassium supplements, salt substitutes containing potassium, potassium-sparing medicines such as spironolactone (used to increase potassium levels in blood)
- Heparin, warfarin (treats blood clot)
- Non-steroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen, indomethacin, or selective cyclooxygenase-2 (Cox-2) inhibitors such as celecoxib (treats pain and inflammation)
- Lithium (used to treat psychiatric illness)
- Furosemide (used to increase the amount of urine)
- Nitroglycerine (treats angina pectoris)
- Rifamycin (treats infections)
- Ciclosporin (used to prevent rejection of transplanted organs)
- Ritonavir (used to treat HIV/AIDS)
- Metformin (treats diabetes)
Overdosage:
If you or anyone else take too much of VYMADA 100MG, contact your doctor immediately or go to a nearest hospital straight away. Overdosage symptoms of VYMADA 100MG includes severe dizziness and fainting.
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