Velpanat Tablet (Sofosbuvir 400mg / Velpatasvir 100mg)

Description

Velpanat Tablet is a combination medicine used for the treatment of chronic hepatitis C infection. It may also be used in combination with ribavirin for patients with advanced cirrhosis. This medicine is not recommended for use in patients with a known history of hepatitis B infection due to the increased risk of serious adverse reactions.

Side effects

Major & minor side effects for Velpanat Tablet
Tiredness
Difficulty in breathing
Cough
Lower back pain
Headache
Rash
Irritability
Diarrhea
Nausea
Decreased appetite
Muscle pain and cramps

Uses of Velpanat Tablet

What is it prescribed for?
Chronic Hepatitis C
This medicine is used in the treatment of chronic hepatitis C virus infection for preventing the growth and spread of the virus in the body. It may also be used in combination with ribavirin for patients with decompensated cirrhosis.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to velpatasvir, sofosbuvir, or any other inactive ingredients present in the formulation.

Warnings
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
Use in Children
This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.
Hepatitis B
This medicine should be used with extreme caution in patients with a known history of hepatitis B due to the increased risk of reactivation of hepatitis B infection. This may cause serious liver problems including liver failure and death. Screening for hepatitis B prior to beginning treatment, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
Use with amiodarone
This medicine should be used with extreme caution in combination with amiodarone due to the increased risk of life-threatening cardiac complications including fatal cardiac arrest. This risk is especially higher in the first 48 hours of starting treatment with both these medicines. Coadministration of these medicines should be done only under close medical supervision with provisions to continuously monitor all vital signs of the patient. Replacement with a suitable alternative may be done based on the clinical condition.
Kidney Disease
This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be done based on the clinical condition.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

General Instructions
Take this medicine with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.