Topnac-TH Tablet (Aceclofenac 100mg / Thiocolchicoside 4mg)

About Topnac-Th Tablet 10’S

Topnac-Th Tablet 10’S is a combination medication used to reduce and relieve pain due to muscle spasms (painful muscular contractions) associated with degenerative vertebral disorders, vertebral static problems, dorsal pain, low back pain, and torticollis (neck muscle contractions).

Topnac-Th Tablet 10’S is a combination of two drugs: Thiocolchicoside (muscle relaxant) and Aceclofenac (a non-steroidal anti-inflammatory drug). Thiocolchicoside is a muscle relaxant that works on the centres of spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms. Aceclofenac is a non-steroidal anti-inflammatory drug (pain killer) that works by blocking the action of cyclo-oxygenase (COX) enzyme in the body involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling.

Take Topnac-Th Tablet 10’S with or after food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take your tablets based on your medical condition. You may experience diarrhoea, dizziness, nausea, vomiting, stomach pain, or increased liver enzymes in the blood in some cases. Most of these side effects of Topnac-Th Tablet 10’S do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Topnac-Th Tablet 10’S or any other medicines, please tell your doctor. Topnac-Th Tablet 10’S is not recommended for children below 18 years of age. Avoid taking Topnac-Th Tablet 10’S if you are pregnant as it may cause harm to the foetus. Topnac-Th Tablet 10’S is excreted in breast milk. Therefore, Topnac-Th Tablet 10’S is contraindicated in breastfeeding women as it may cause adverse effects in the baby. If you have asthma, diabetes, high blood pressure, stomach ulcer, high cholesterol, chickenpox, porphyria (rare inherited disorder), systemic lupus erythematosus (an autoimmune disease), ulcerative colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss), galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), fits, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), bleeding or blood clotting disorders, kidney, liver or heart diseases, inform your doctor before taking Topnac-Th Tablet 10’S.

Uses of Topnac-Th Tablet 10’S

Pain due to muscle spasms

Medicinal Benefits

Topnac-Th Tablet 10’S is a combination of two drugs, namely: Thiocolchicoside and Aceclofenac, used to treat pain due to muscle spasms. Thiocolchicoside is a muscle relaxant that works on the centres of spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements, thereby relieves pain due to muscle spasms. Aceclofenac is a non-steroidal anti-inflammatory drug (pain killer) that works by blocking the action of cyclo-oxygenase (COX) enzyme in the body that is involved in the production of certain chemical substances such as prostaglandins that cause pain and swelling.

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Directions for Use

Take Topnac-Th Tablet 10’S with or after food as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Topnac-Th Tablet 10’S

• Diarrhoea
• Dizziness
• Nausea
• Vomiting
• Stomach pain
• Increased liver enzymes in the blood

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Topnac-Th Tablet 10’S or any other medicines, please tell your doctor. Topnac-Th Tablet 10’S is not recommended for children below 18 years of age. Avoid taking Topnac-Th Tablet 10’S if you are pregnant as it may cause harm to the foetus. Topnac-Th Tablet 10’S is excreted in breast milk. Therefore, Topnac-Th Tablet 10’S is contraindicated in breastfeeding women as it may cause adverse effects in the baby. Do not consume alcohol with Topnac-Th Tablet 10’S as it may increase the risk of severe adverse effects. If you have asthma, diabetes, high blood pressure, stomach ulcer, high cholesterol, chickenpox, porphyria (rare inherited disorder), systemic lupus erythematosus (an autoimmune disease), ulcerative colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss), galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), fits, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), bleeding or blood clotting disorders, kidney, liver or heart diseases, inform your doctor before taking Topnac-Th Tablet 10’S.

Drug Interactions

Drug-Drug Interaction: Topnac-Th Tablet 10’S may have interaction with medicines used to lower high blood pressure (lisinopril, enalapril, candesartan, losartan, clonidine, moxonidine, hydralazine, methyldopa, propranolol), antibiotics (ciprofloxacin, moxifloxacin, ofloxacin, levofloxacin), water pills (furosemide, amiloride), blood thinners (heparin, warfarin, clopidogrel), anticancer drug (methotrexate), HIV drug (zidovudine), antidiabetic drugs (gliclazide, tolbutamide, glibenclamide), pain killers (ibuprofen, naproxen, aspirin, celecoxib, etoricoxib), steroids (hydrocortisone, prednisolone), medicines used for abortion (mifepristone), immunosuppressants (ciclosporin, tacrolimus), antimanic drug (lithium), heart-related medicines (digoxin), and antidepressants (fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, escitalopram).

Drug- Food Interaction: Avoid the intake of alcohol with Topnac-Th Tablet 10’S as it may increase the risk of severe adverse effects.

Drug-Disease Interaction: If you have asthma, diabetes, high blood pressure, stomach ulcer, high cholesterol, chickenpox, porphyria (rare inherited disorder), systemic lupus erythematosus (an autoimmune disease), ulcerative colitis or Crohn’s disease (conditions causing swelling of the bowel, diarrhoea, bowel pain, vomiting and weight loss), galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, G-6-PD deficiency (a hereditary condition resulting in low red blood cell counts), fits, muscular hypotonia (decreased muscle tone), flaccid paresis (loose and floppy limbs), bleeding or blood clotting disorders, kidney, liver or heart diseases, inform your doctor before taking Topnac-Th Tablet 10’S.