Takfa Forte Lotion (Tacrolimus 0.1%)

About Takfa Forte Lotion 20 ml

Takfa Forte Lotion 20 ml belongs to a class of drugs called ‘immunosuppressants‘ used to treat moderate to severe atopic dermatitis (eczema) and prevent organ rejection after a transplant. Atopic dermatitis, also known as eczema is a common skin condition associated with inflamed and itchy skin patches. The symptoms include itchy, dry, flaky, swollen, rough and irritated skin. Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Takfa Forte Lotion 20 ml contains ‘Tacrolimus‘ that works by suppressing the over-reaction of immune cells in the skin to a stimulus. Thereby, reduces allergic reaction and inflammation (redness and swelling). Also, Takfa Forte Lotion 20 ml suppresses T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. Thereby prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

Use Takfa Forte Lotion 20 ml as prescribed by your doctor. You are advised to use Takfa Forte Lotion 20 ml for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience itching, burning sensation, redness, pain, skin tingling, nausea, diarrhoea, headache, increased blood sugar levels, kidney problems, dizziness or stomach pain. Most of these side effects of Takfa Forte Lotion 20 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Takfa Forte Lotion 20 ml or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Takfa Forte Lotion 20 ml. Avoid alcohol consumption with Takfa Forte Lotion 20 ml as it may increase the risk of severe adverse effects. Drive only if you are alert as Takfa Forte Lotion 20 ml may cause drowsiness, dizziness or vision problems. Do not cover or wrap the treated area with bandage or dressing.  Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Takfa Forte Lotion 20 ml catches fire and burns easily.

Uses of Takfa Forte Lotion 20 ml

Atopic dermatitis (eczema), Organ transplant

Medicinal Benefits

Takfa Forte Lotion 20 ml contains Tacrolimus, an immunosuppressant used to treat moderate to severe atopic dermatitis (eczema) and prevent organ rejection after a transplant.  Takfa Forte Lotion 20 ml suppresses the over-reaction of immune cells in the skin to a stimulus. Thereby, reduces allergic reaction and inflammation (redness and swelling). Also, Takfa Forte Lotion 20 ml suppresses T and B lymphocytes (cells in the immune system) that normally attacks foreign invaders and defend the body against foreign cells and infection. Thereby prevents organ rejection in transplanted patients and helps the body in accepting the new organ.

Related Product

Directions for Use

Wash your hands before and after applying Takfa Forte Lotion 20 ml. The topical form of Takfa Forte Lotion 20 ml can be applied as a thin layer on the clean and dry affected area of the skin as prescribed by your doctor. Takfa Forte Lotion 20 ml is only for external use. Please avoid contact with eyes, nose or mouth as it may irritate. In case Takfa Forte Lotion 20 ml comes in contact with these areas accidentally, rinse with water thoroughly. Take Takfa Forte Lotion 20 ml on an empty stomach or at least 1 hour before or 2-3 hours after a meal. Takfa Forte Lotion 20 ml in oral form can be swallowed as a whole with a glass of water. Do not break, chew or crush it. The granules form can be mixed with water just before taking. The injection form of Takfa Forte Lotion 20 ml is given as an intravenous (into a vein) infusion by a doctor or nurse. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Takfa Forte Lotion 20 ml

• Itching
• Burning sensation
• Redness
• Pain
• Skin tingling
• Nausea
• Diarrhoea
• Headache
• Increased blood sugar levels
• Kidney problems
• Dizziness
• Stomach pain

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Takfa Forte Lotion 20 ml or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Takfa Forte Lotion 20 ml. Avoid alcohol consumption with Takfa Forte Lotion 20 ml as it may increase the risk of severe adverse effects. Drive only if you are alert as Takfa Forte Lotion 20 ml may cause drowsiness, dizziness or vision problems. Do not cover or wrap the treated area with bandage or dressing.  Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Takfa Forte Lotion 20 ml catches fire and burns easily. Please avoid contact with eyes, nose or mouth as it may irritate. Do not shower, bathe or swim immediately after applying Takfa Forte Lotion 20 ml as it may wash off Takfa Forte Lotion 20 ml. In case Takfa Forte Lotion 20 ml comes in contact with these areas accidentally, rinse with water thoroughly. Do not swallow Takfa Forte Lotion 20 ml. In case of accidental swallowing, consult a doctor immediately.

Drug Interactions

Drug-Drug Interaction: Takfa Forte Lotion 20 ml may interact with immunosuppressant (ciclosporin), antibiotics (fluconazole, itraconazole, ketoconazole, clotrimazole, voriconazole, erythromycin, clarithromycin, rifampicin), antiemetic (metoclopramide), anticonvulsants (phenytoin, phenobarbital), antacids (lansoprazole, cimetidine, omeprazole), steroid (cortisone, prednisolone, methylprednisolone), antivirals (aciclovir), pain reliever (ibuprofen), an antidepressant (nefazodone), anticancer drugs (imatinib, nilotinib), anti-HIV drugs (nelfinavir, saquinavir, ritonavir).

Drug-Food Interaction: Takfa Forte Lotion 20 ml may interact with St. John’s Wort (a herbal supplement to treat depression) or extracts of Schisandra sphenanthera. Avoid taking grapefruit and grapefruit juice with Takfa Forte Lotion 20 ml as it may cause serious side effects. Also, avoid consumption of alcohol with Takfa Forte Lotion 20 ml as it may cause flushing (make face or skin feel warm and hot) and increase other adverse effects.

Drug-Disease Interaction: If you have skin tumours, weakened immune system, infected lesions, cutaneous Graft Versus Host Disease (an immune reaction of the skin in patients who had bone marrow transplant), generalised erythroderma (inflammatory scaling and redness of entire skin), Netherton’s syndrome, lamellar ichthyosis (extensive scaling of skin), diarrhoea for more than a day, stomach pain with or without symptoms such as nausea, chills, fever or vomiting, liver or heart problems, inform your doctor before taking Takfa Forte Lotion 20 ml.