Religrast 300mcg Injection (Filgrastim 300mcg)

Description

Religrast 300 mcg Injection is a human granulocyte colony-stimulating factor (G-CSF) analog. It stimulates the growth of white blood cells and helps in decreasing the chances of infection in patients who are undergoing chemotherapy procedures for cancer. Patients with blood disorders are advised not to use this medicine.

Substitutes

List of substitutes for Religrast 300 mcg Injection
Grafeel 300 mcg Injection
Dr. Reddys Laboratories Ltd.
Itact 300 mcg Injection
Zuventus Healthcare Ltd.
Lupifil 300 mcg Injection
Lupin Ltd.
Xgrast 300 mcg Injection
Emcure Pharmaceuticals Ltd.
Endokine 300 Injection
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Religrast 300 mcg Injection
Stomach pain
Hair loss
Constipation
Nausea or Vomiting
Fever and chills
Bone pain
Loss of appetite
Weight loss
Swelling or inflammation of mouth

Uses of Religrast 300 mcg Injection

What is it prescribed for?
Neutropenia caused by chemotherapy
This medicine is used to reduce the incidence of infection in patients receiving myelosuppressive anti-cancer drugs.
Bone Marrow Transplantation
This medicine is used to treat febrile neutropenia, the fever caused due to decreased neutrophil count in patients receiving chemotherapy followed by bone marrow transplantation.
Peripheral Progenitor Cell Transplantation
This medicine is used before the procedure of leukapheresis to mobilize the autologous hematopoietic progenitor cells into the peripheral blood for collection.
Chronic Neutropenia
This medicine is used to reduce the incidence of infection, fever, and oropharyngeal ulcers in patients with chronic neutropenia.
Neutropenia caused by radiation
This medicine is used to increase the survival rate in patients who have received high doses of myelosuppressive radiation.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to filgrastim or any other inactive ingredients present in the formulation.

Warnings

Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings
Splenic Rupture
This medicine should be used with caution due to the increased risk of splenic rupture. Patients having abdominal and/or shoulder tip pain while taking this medicine should consult the doctor immediately. Your doctor may advise you to stop the medicine based on your clinical condition.
Acute Respiratory Distress Syndrome (ARDS)
This medicine has been shown to cause Acute respiratory distress syndrome in rare cases. Discuss the risks and benefits with your doctor before taking this medicine. Report any symptoms of fever or respiratory distress to the doctor on priority. Replacement with a suitable alternative might be required based on the clinical condition.
Sickle cell crisis
This medicine not recommended for use in patients with a known history of sickle cell disease due to the increased risk of serious and life threatening reactions. Discuss the risks and benefits with your doctor before taking this medicine. Replacement with a suitable alternative might be required based on the clinical condition.
Other medicines
This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Dosage

Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

General Instructions
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.