Provanol SR 80 Tablet (Propranolol 80mg)

INTRODUCTION

PROVANOL SR 80MG contains Propranolol which belongs to a group of medicines called beta-blockers, which have effects on the heart and circulation of the body. It is used to treat hypertension, angina, arrythmias (disorders of heart rhythm), migraine and proliferating infantile hemangioma.

Propranolol is a nonselective beta-adrenergic receptor blocking agent which specifically competes with beta-adrenergic receptor agonist agents for available receptor sites. By blocking the response to beta 1 and beta 2 adrenergic stimulation, it helps in decreasing the heart rate, myocardial contractility, blood pressure, and myocardial oxygen demand. It reduces portal pressure by producing splanchnic vasoconstriction thereby reducing portal blood flow.

Before taking PROVANOL SR 80MG, tell your doctor if you have asthma, heart, kidney or liver problems. It is not recommended for use during pregnant and breastfeeding. The common side effects are tiredness, weakness cold fingers and toes, irregular or slow heartbeat, numbness in your fingers and breathlessness.

USES OF PROVANOL SR 80MG

Treat hypertension (high blood pressure), angina (chest pain), arrythmias (disorders of heart rhythm), phaeochromocytoma, migraine and proliferating infantile hemangioma

HOW PROVANOL SR 80MG WORKS

PROVANOL SR 80MG works by blocking the action of certain natural chemicals in your body that affect the heart and blood vessels. This effect reduces heart rate, blood pressure and strain on the heart.

DIRECTIONS FOR USE

Always take PROVANOL SR 80MG as your doctor has directed you. Swallow this medicine with a drink of water before meal and do not chew.

SIDE EFFECTS OF PROVANOL SR 80MG

COMMON
Cold fingers and toes
Slow heartbeat
Numbness and spasm in the fingers
Disturbed sleep or nightmares
Fatigue
Breathlessness
RARE
Worsening of breathing difficulty
Worsening of heart problems
Swelling of the skin which may occur in the face, tongue, larynx, abdomen, or arms and legs
Dizziness
Worsening of blood circulation
Hair loss (alopecia)
Mood changes, confusion or memory loss
Psychosis or hallucinations
Paraesthesia
Disturbances of vision, dry eyes
Skin rash, including worsening of psoriasis
Reduction in the number of platelets
Purple spots on the skin

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HOW TO MANAGE SIDE EFFECTS

Cold hands and toes:

Wear gloves and socks to keep warm. Exercise daily to improve blood circulation and briskly massage hands or feet.

Disturbed sleep:

Maintain a regular bedtime, exercise regularly and avoid naps and go to bed only when sleepy.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

WARNING & PRECAUTIONS

PREGNANCY
PROVANOL SR 80MG is not recommended during pregnancy, unless your doctor considers it necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING
PROVANOL SR 80MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES
PROVANOL SR 80MG may cause dizziness or tiredness. Do not drive or handle any machines while taking this medicine.

ALCOHOL
Consumption of alcohol is not recommended during treatment with PROVANOL SR 80MG.

KIDNEY
PROVANOL SR 80MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER
PROVANOL SR 80MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY
Do not take if you are allergic (hypersensitive) to Propranolol.

HEART DISEASE
PROVANOL SR 80MG is not recommended in patients with severe heart disease. Consult your doctor for advice.

OTHERS

Inform your doctor if you have or had a condition such as,

Increased acidity of the blood (metabolic acidosis)
Are on a strict fasting diet
Asthma, wheezing, chronic obstructive pulmonary disease and bronchospasm
Untreated phaeochromocytoma
Severe blood circulation problems
Prinzmetal’s angina
Decrease in blood pressure
Diabetes
Allergic reactions
Thyrotoxicosis
Muscle weakness

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

Verapamil, diltiazem
Nifedipine, nisoldipine, nicardipine, isradipine, lacidipine and hydralazine (used to treat hypertension or angina)
Lidocaine (local anesthetic)
Disopyramide, quinidine, amiodarone, propafenone, adrenaline and glycosides (treats heart problems)
Ibuprofen and indometacin (treats pain and inflammation)
Ergotamine, dihydroergotamine or rizatriptan (used for migraine)
Chlorpromazine, mao inhibitors and thioridazine (used for certain psychiatric disorders)
Cimetidine (treats stomach problems)
Rifampicin (used to treat tuberculosis)
Theophylline (used for asthma)
Warfarin (used to thin blood)
Fingolimod (treats multiple sclerosis)
Fluvoxamine and barbiturates (used to treat anxiety and insomnia)
Clonidine (used for hypertension or migraine)