Noklot Tablet (Clopidogrel 75mg)

Noklot Tablet

Noklot 75 MG Tablet is used to reduce atherosclerotic events (myocardial infarction, stroke, vascular deaths) in patients with atherosclerosis documented by recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Noklot 75 MG Tablet is an anti-platelet drug which prevents the clotting of blood in the blood vessels. People with heart problems or a blood vessel disorder can reduce their chances of suffering from heart attack or stroke by taking this medicine everyday.

This medicine is also helpful in prevention of thrombotic complications after coronary stenting. To make sure this medicine is safe for you, inform your doctor if you have any of the following conditions :

Pregnant or breast-feeding.
A bleeding disorder, liver or kidney problems or an allergic reaction to a medicine.
Have recently had surgery or an injury.
Are taking any other medicines like escitalopram, fluconazole, non-steroidal anti inflammatory drugs and isoniazid.
The usual dose prescribed for this tablet is 75mg. Skip your missed dose if you do not remember until more than 12 hours of the missed dose. Try to keep regular appointments with your doctor.

Take as directed. May cause headache or dizziness; use caution when driving or engaging in tasks that require alertness until response to drug is known. Small frequent meals, frequent mouth care, sucking lozenges, or chewing gum may reduce nausea or vomiting.

Mild analgesics may reduce arthralgia or back pain. Report immediately unusual or acute chest pain or respiratory difficulties, skin rash, unresolved diarrhea or gastrointestinal distress, nosebleed, or acute headache.

Noklot 75 MG Tablet may be considered in aspirin-intolerant patients. It has not been as extensively studied as aspirin or even ticlopidine when used in patients with coronary artery disease.

When used instead of aspirin, cost may become an issue. In one study (CAPRIE), small but significantly superior effects of clopidogrel versus aspirin occurred in patients at risk for ischemic events.

For the prevention of thrombotic complications, clopidogrel is similar in efficacy to ticlopidine and is not associated with neutropenia.

Symptoms of acute toxicity include vomiting, prostration, difficulty breathing, and gastrointestinal hemorrhage. Only one case of overdose with clopidogrel has been reported to date, no symptoms were reported with this case and no specific treatments were required.

Based on its pharmacology, platelet transfusions may be an appropriate treatment when attempting to reverse the effects of clopidogrel. After decontamination, treatment is symptomatic and supportive.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Hematologist before using this medicine.

Use

This drug is used to treat:

Acute Coronary Syndrome

Ischemic Stroke

Myocardial Infarction

Heart Attack And Stroke

Side Effects

The side effects of this drug include:

Chest Pain

Edema (Swelling)

Hypertension

Headache

Dizziness

Depression

Fatigue

Pain

Rash

Abdominal Pain

Dyspepsia

Diarrhoea

Nausea

Hemorrhage

Urinary Tract Infection

Arthralgia

Back Pain

Rhinitis

Bronchitis

Dosage

Are there any missed dose instructions?

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it’s already time for your next scheduled dose.
Are there any overdose instructions?

Seek emergency medical treatment or contact the doctor in case of overdose.

Work

The active constituent of this medicine behaves as a prodrug with anticoagulatory properties that is broken down by CYP450 enzymes to its active metabolite that prevents adenosine diphosphate (ADP) from binding to its platelet P2Y12 receptor. This inhibits the ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, which in turn inhibits coagulation.