Losartas-HT Tablet (Losartan 50mg / Hydrochlorothiazide 12.5mg)

Medical Description

Losartas Ht Tablet is a combination of Hydrochlorothiazide and Losartan. It is an antihypertensive medicine.

Uses of Losartas Ht Tablet

Treatment of high blood pressure when Hydrochlorothiazide and Losartan alone is not able to control blood pressure

Contraindications of Losartas Ht Tablet

If you are allergic to this medicine or any of the ingredient of this medicine
If you are allergic to sulfonamide medicines such as co-trimoxazole
If you have a low level of potassium & sodium or high levels of calcium in your blood
If you have serious liver disorders and problems related to bile duct (canal connecting liver to intestine) like cholestasis
If you have kidney disease due to which you are not producing enough urine
If you have diabetes or kidney problem and taking a medicine for high blood pressure like Aliskiren
If you have gout
If you are pregnant for more than 3 months

Side effects of Losartas Ht Tablet

Cough, nasal congestion and sinusitis
Nausea, diarrhoea, stomach pain and indigestion
Chest pain and tiredness
Muscle pain, back pain and pain in the legs
Headache, weakness, dizziness and sleeplessness
Kidney and liver dysfunction
Low blood sugar levels

Other General Warnings

Talk to your doctor if
If you have a history of swelling of face, lips, throat or tongue due to water retention
If you have blocked arteries of your kidneys or recently had a kidney transplant or have only one functioning kidney
If you experience fainting and giddiness especially after the first dose
If you are planning a pregnancy, this medicine will be changed
If you are facing problems with liver function and related organs-like cholestasis and biliary obstructive
If your kidneys are not functioning correctly or you have underlying kidney disease like renal artery stenosis (Narrow kidney blood vessels)
If you have been experiencing fluid losses within your body due to diarrhoea, vomiting, etc.
If you have serious heart valve-related problems like congestive heart failure, aortic or mitral stenosis and ischaemic cardiopathy
If you are suffering from primary aldosteronism (a condition of excess production of the hormone aldosterone from the adrenal glands)
If you have diabetes as this medicine may affect your blood glucose levels, glucose monitoring is needed
If you have electrolyte imbalance of sodium, magnesium, potassium and have symptoms of dryness of mouth, thirst, drowsiness, muscle pain, nausea, vomiting, etc.
If you have galactose intolerance (small intestine’s inability to transport and absorb glucose and galactose)
If you develop eye pain and decrease in vision
If you had any skin cancer or developed any skin lesions
If you have gout, diabetes, bronchial asthma or any autoimmune diseases like systemic lupus erythematosus

Mode of Action of Losartas Ht Tablet

How Does It Work?
Telmisartan lowers the blood pressure by blocking the action of a hormone called angiotensin responsible for narrowing of blood vessels and rise in blood pressure. Hydrochlorothiazide acts by increasing the production of urine and loss of water and salt from body, thereby lowering the blood pressure. Both the medicines act by different mechanisms resulting in effective control of blood pressure.

Directions for Use of Losartas Ht Tablet

This medicine should be consumed as a whole with a sufficient amount of water with or without food
Do not change your dose unless your doctor tells you to do. Never stop this medicine on your own
This medicine tends to catch moisture and should be taken out from blister just before use

Interactions of Losartas Ht Tablet

Interactions with other medicines
Your blood potassium levels may go down if you are taking steroids, antifungals like Amphotericin
Medicines used to treat depression or other mental conditions like Lithium, Thioridazine and Chlorpromazine
Your blood potassium levels may increase if you are taking potassium supplements (Amiloride, Spironolactone) and Trimethoprim
You may experience low blood sugar if you are taking medicine for diabetes like Insulin and Metformin along with this medicine (severe kidney problems may also arise with Metformin)
This medicine can decrease your blood pressure abruptly if taken with other blood pressure-lowering medicine
Your blood cell production may be hampered if you take this with medicines like Cyclophosphamide and Methotrexate
Medicines used to treat pain and inflammation like Aspirin, Ibuprofen and Naproxen interferes the way this medicine works
You may experience anemia if you are taking medicine like Methyldopa
Concomitant use of Cyclosporin may increase the risk of gout
You may experience abnormal heart rhythms if you are taking medicine for heart failure like Digoxin
Medicines which may not be able to work properly due to increased potassium levels which are used to treat irregular heartbeats like Quinidine, Sotalol and Amiodarone
This medicine can increase blood calcium levels if you are taking vitamin D and calcium supplements
Other medicines like Probenecid, Allopurinol, Atropine, Biperiden and muscle relaxants like Tubocurarine, Cholestyramine and Colestipol
Interactions with food items
Make sure to have a low salt diet because excess salt in your diet may decrease the effects of this medicine.

Storage and disposal of Losartas Ht Tablet

Store this medicine below 30°C
Keep this medicine in the original container to protect it from light and moisture

Dosage of Losartas Ht Tablet

Overdose
Symptoms of overdose may include low blood pressure, irregular heart rhythms, dizziness, excessive urination, nausea and vomiting. If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
It would be best if you never miss a dose of your blood pressure medicine as it may lead to serious high blood pressure-related problems
If you missed any dose, take it as soon as you remember
If it is time for the next dose, skip the missed dose and continue with your regular dosing schedule
Do not take a double dose of this medicine to compensate for the missed one