Ketocip Tablet (Ketoconazole 200mg)

INTRODUCTION

KETOCIP contains Ketoconazole belongs to the class of drugs called azole antifungals. It is used to treat fungal infections including blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. It gets bound to proteins such as albumin in the circulating blood and is widely distributed in body tissues. This medicine works by binding to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall which is necessary for them to grow.

Always take this medicine as directed by physician. Your doctor will decide the dose and duration of therapy depending upon your age, weight and condition. Swallow the medicine with a glass of water. It is recommended for the use in children and adolescents. Do not take this medicine, if you have adrenal insufficiency. It is not recommended for use in pregnant or breastfeeding women. Consult your doctor before taking this medicine. Tell your doctor, if you are taking or taken or might take any other medicines. The most common side effects include diarrhea, nausea, headache, stomach pain and abnormal liver function test.

USES OF KETOCIP

Treat fungal infections in the body

HOW KETOCIP WORKS

KETOCIP binds to the fungal p450 enzymes and stops the cells making ergosterol of the cell wall which is necessary for them to grow.

DIRECTIONS FOR USE

Always take KETOCIP exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. If you take more this medicine than you should, talk to your doctor.

SIDE EFFECTS OF KETOCIP

SERIOUS
Long-lasting severe headache or blurred vision
Severe lack of appetite (anorexia)
Weight loss
Allergic reactions such as rash, itching, hives, fever, swelling of the lips or tongue, chest pain, or trouble breathing
Unusual tiredness
Muscle weakness
Yellowing of skin or whites of the eyes
COMMON
Nausea
Headache
Abdominal pain
Diarrhea
Abnormal liver function tests

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HOW TO MANAGE SIDE EFFECTS

Skin rash:

Avoid bath in hot water because hot water can irritate the skin. Moisturizers can be used regular basis to soothe and hydrate the affected area.

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Diarrhea:

Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.

WARNING & PRECAUTIONS

PREGNANCY
KETOCIP is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING
KETOCIP is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES
Do not drive or operate any machinery while taking this medicine, it may make you feel dizzy.

ALCOHOL
Consumption of alcohol is not recommended during treatment with KETOCIP.

KIDNEY
KETOCIP should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER
KETOCIP should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY
Do not take if you are allergic to this medicine.

HEART DISEASE
If you have any heart related problems, consult your doctor for advice before taking this medicine.

INTERACTIONS

Talk to your doctor, if you are taking:

Medicines for lowering blood cholesterol such as simvastatin, atorvastatin, lovastatin
Heart medicines such as epleronone, dronedarone, disopyramide, felodipine, nisoldipine
Medicines used for the treatment of the paludism such as quinidine, halofantrine
Medicines used for severe mental health disorders and severe depression such as pimozide, sertindole, lurasidone, quetiapine
Medicines used for the allergies such as mizolastine
Dabigatran
Medicine used to prevent the formation of blood clots
Medicines to help to sleep and for anxiety such as triazolam, alprazolam, midazolam (taken by mouth)
Medicines used for migraine attacks such as dihydroergotamine, ergometrine (ergonovine)
Medicines used in cancers such as irinotecan, everolimus
Sirolimus such as used to prevent your body from rejecting a kidney transplant