Keppra 500mg Tablet (Levetiracetam 500mg)

COMMON

• Inflammation of nose and throat (nasopharyngitis)
• Somnolence (excessive sleepiness)
• Headache
• Loss of appetite
• Depression, aggression, anxiety
• Insomnia, nervousness, irritability
• Convulsion, balance disorder
• Dizziness
• Lethargy, tiredness
• Tremor (involuntary trembling)
• Vertigo (sensation of rotation or spinning)
• Cough
• Abdominal pain
• Diarrhoea, indigestion
• Vomiting, nausea
• Rash

UNCOMMON

• Decreased number of blood platelets (easy bruising, more bleeding, bleeding from gums or nose)
• Decreased number of white blood cells (chills, fever, body ache, headache)
• Weight decrease or increase
• Panic attack, emotional instability, mood swings
• Loss of memory, forgetfulness, abnormal or impaired coordination
• Paraesthesia (tingling)
• Disturbance in attention (loss of concentration)
• Double vision, vision blurred
• Hair loss, eczema
• Muscle weakness, muscle pain

RARE

• Infection
• Decreased blood sodium concentration
• Delirium
• Seizures may become worse or happen frequently
• Uncontrollable muscle spasms affecting the head, body and limbs
• Difficulty in controlling movements, hyperactivity
• Change of the heart rhythm (Electrocardiogram)
• Pancreatitis
• Liver failure, hepatitis (abdominal pain, dark urine, itching, light coloured stools, jaundice, swelling of the abdomen)
• Rhabdomyolysis (breakdown of muscle tissue)
• Limp or difficulty in walking
• Fever, unstable blood pressure and heart rate, muscle stiffness, low level of consciousness, confusion (signs of a disorder called neuroleptic malignant syndrome)

Stop taking KEPPRA 500MG TABLET and inform your doctor immediately if you experience any of the following side effects:

• Signs of anaphylactic reaction (weakness, light-headedness, dizziness or have difficulty breathing)
• Signs of Quincke’s oedema (swelling of the face, lips, tongue and throat)
• Signs of Drug Reaction with Eosinophilia and Systemic Symptoms (flu-like symptoms, rash on the face followed by an extended rash with a high temperature, enlarged lymph nodes)
• Signs of sudden decrease of kidney function (low urine volume, tiredness, nausea, vomiting, confusion and swelling in the legs, ankles or feet)
• Signs of erythema multiforme (skin rash which may form blisters and look like small targets like central dark spots surrounded by a paler area, with a dark ring around the edge)
• Signs of Stevens-Johnson syndrome (widespread rash particularly around the mouth, nose, eyes and genitals, with blisters and peeling skin)
• Signs of toxic epidermal necrolysis (severe form of rash causing skin peeling in more than 30% of the body surface)
• Signs of serious mental changes that can be symptoms of encephalopathy (confusion, sleepiness, loss of memory, forgetfulness, abnormal behaviour, involuntary or uncontrolled movements)
• Abnormal thoughts, feeling irritable or reacting more aggressively
• Aggravation (worsening) of epilepsy

PREGNANCY

KEPPRA 500MG TABLET should be used with caution in pregnant women only if considered clearly necessary by the doctor. Consult your doctor before taking KEPPRA 500MG TABLET.

BREASTFEEDING

KEPPRA 500 MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking the medicine.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel sleepy after taking KEPPRA 500 MG TABLET.

ALCOHOL

Avoid the consumption of alcohol while taking KEPPRA 500 MG TABLET.

KIDNEY

KEPPRA 500 MG TABLET should be used with caution in patients with kidney disease. Consult with your doctor before taking the medicine.

ALLERGY

Do not take KEPPRA 500 MG TABLET if you are allergic to Levetiracetam or to any other ingredients of this medicine.

HEART DISEASE

KEPPRA 500MG TABLET should be used with caution in patients with heart diseases such as family or medical history of irregular heart rhythm (visible on an electrocardiogram), or if you are prone to heartbeat irregularities. Consult your doctor before taking KEPPRA 500MG TABLET.

OTHERS

Before taking KEPPRA 500MG TABLET tell your doctor if you:

• Have salt imbalances

Use in pediatrics:

KEPPRA 500MG TABLET is not recommended for use in children and adolescents under 16 years of age if used alone. However, KEPPRA 500MG TABLET can be used in children and adolescents in combination with other medicines. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition.

Use in geriatrics:

Your doctor will decide the correct dose and duration of the treatment depending upon your age, disease condition and body weight. Consult your doctor before taking KEPPRA 500MG TABLET.