Entofoam Rectal Foam is a prescription rectal corticosteroid formulation intended to deliver anti-inflammatory medicine directly to the lower rectal area. When the active ingredient is hydrocortisone acetate 10%, it helps reduce local inflammation and associated symptoms of ulcerative proctitis. The FDA-approved hydrocortisone acetate 10% rectal foam formulation is used as adjunctive therapy for ulcerative proctitis affecting the distal rectum, particularly in patients who cannot retain hydrocortisone or other corticosteroid enemas.

Entofoam Rectal Foam does not provide a permanent cure for inflammatory bowel disease. Instead, corticosteroid therapy works by reducing inflammation so that symptoms can improve while the underlying condition receives appropriate medical management. Patients should use this type of treatment only according to the directions provided by their healthcare professional.

How Entofoam Rectal Foam Works

The active corticosteroid in the comparable U.S. hydrocortisone acetate foam product acts locally as an anti-inflammatory medicine. Entofoam Rectal Foam delivers the medication directly into the rectal area, allowing treatment to target inflammation where it occurs. FDA labeling reports that the foam can reach approximately 10 centimeters into the rectum.

By reducing inflammatory activity, Entofoam Rectal Foam may help decrease symptoms associated with distal ulcerative proctitis. These symptoms can include rectal discomfort, urgency, irritation, and bleeding associated with active inflammation. However, rectal bleeding can have several causes, so patients should not automatically assume that bleeding results from ulcerative proctitis.

Uses and Benefits

Entofoam Rectal Foam is primarily relevant to patients who require topical corticosteroid therapy for inflammation in the distal rectum. A healthcare professional may recommend this treatment when local therapy offers an appropriate approach.

One benefit of Entofoam Rectal Foam is its topical delivery. Instead of relying exclusively on an oral medicine to reach the affected area, rectal foam places the medication directly within the lower rectum. This approach can be particularly useful when inflammation remains concentrated in the distal portion of the bowel.

Entofoam Rectal Foam may also offer an alternative for patients who have difficulty retaining liquid corticosteroid enemas. The FDA labeling specifically describes hydrocortisone acetate rectal foam as adjunctive therapy for patients who cannot retain hydrocortisone or other corticosteroid enemas.

Directions for Use

Use Entofoam Rectal Foam exactly as prescribed. Do not increase the amount, frequency, or duration of treatment unless your prescriber tells you to do so. The administration technique matters because incorrect use can reduce the amount of medicine delivered to the intended area.

For the FDA-labeled hydrocortisone acetate 10% foam formulation, the container should be shaken vigorously for 5–10 seconds before each use and kept upright during administration. The supplied applicator is used according to the product instructions.

Wash your hands before and after administration. Follow the package instructions carefully, and never substitute another applicator or administration method unless your healthcare professional specifically advises you to do so.

Safety Precautions

Because Entofoam Rectal Foam contains a corticosteroid when formulated with hydrocortisone acetate, it can cause unwanted effects and requires appropriate medical supervision. Do not use it if you have previously experienced hypersensitivity to hydrocortisone acetate or any ingredient in the formulation.

Corticosteroids can suppress immune responses and may mask signs of infection. Tell your healthcare professional about infections, persistent fever, unusual rectal symptoms, or other significant health concerns before treatment. Prolonged corticosteroid exposure can also produce systemic corticosteroid effects, particularly when absorption increases.

Entofoam Rectal Foam should not be treated as an ordinary over-the-counter hemorrhoid product. If you have unexplained rectal bleeding, severe abdominal pain, fever, worsening symptoms, or significant weakness, seek medical evaluation rather than simply increasing your medication.

Possible Side Effects

Patients using Entofoam Rectal Foams may experience local irritation or discomfort. Corticosteroids can also cause systemic effects, especially with prolonged or excessive exposure. The risk depends on the strength, treatment duration, absorption, and individual patient factors.

Contact your healthcare professional if symptoms become worse, new irritation develops, or you experience concerning changes during treatment. Do not continue prolonged corticosteroid treatment without appropriate follow-up.

Who Should Discuss This Medicine With a Doctor?

Before starting Entofoam Rectal Foam, discuss your complete medical history with your prescriber. Tell them about allergies, current medicines, infections, recent procedures, and any previous reactions to corticosteroids.

Pregnant or breastfeeding patients should ask their healthcare professional whether the medicine is appropriate. Patients who require repeated corticosteroid courses should also receive appropriate medical monitoring.

Storage and Handling

Store Entofoam Rectal Foam according to the package directions. For the U.S. hydrocortisone acetate 10% foam formulation, the product labeling specifies controlled room-temperature storage of 20–25°C (68–77°F) and states that the product should not be refrigerated.

Keep the container away from excessive heat and keep medicines out of children’s reach. Never use a container that appears damaged or has been stored outside the recommended conditions.

Why Proper Diagnosis Matters

Entofoam Rectal Foam should only be used for the condition for which it was prescribed. Rectal symptoms can result from inflammatory bowel disease, hemorrhoids, infections, fissures, or other conditions. Treating the wrong cause with a corticosteroid can delay appropriate care.

For that reason, Entofoam Rectal Foam works best as part of a complete treatment plan developed with a qualified healthcare professional. Patients should follow scheduled appointments and report changes in symptoms rather than adjusting treatment independently.

Ordering and Pharmacist Guidance

If your healthcare professional has prescribed Entofoam Rectal Foam, verify the exact product name, active ingredient, strength, quantity, and directions before placing an order. Because prescription rectal corticosteroids require appropriate use, a pharmacist can help explain administration, potential interactions, storage, and precautions.

When ordering Entofoam Rectal Foam, use a legitimate pharmacy that requires a valid prescription where applicable. Avoid purchasing medicines from sources that cannot verify product authenticity or provide appropriate pharmacist support.

Frequently Asked Questions

What is Entofoam Rectal Foam used for?

Entofoam Rectal Foam refers to a rectal foam product used to deliver corticosteroid treatment locally. For hydrocortisone acetate 10% rectal foam, the labeled indication is adjunctive treatment of ulcerative proctitis involving the distal rectum.

Does Entofoam Rectal Foam cure ulcerative proctitis?

Entofoam Rectal Foam should not be described as a permanent cure. Hydrocortisone rectal foam reduces inflammation and helps control symptoms as part of a broader treatment plan. Your clinician determines whether additional or maintenance treatment is necessary.

How should Entofoam Rectal Foam be administered?

Use Entofoam Rectal Foam according to your prescription and the manufacturer’s instructions. For the FDA-labeled hydrocortisone acetate foam, the container is shaken before use and kept upright during administration.

Can I use Entofoam Rectal Foam for hemorrhoids?

Do not use Entofoam Rectal Foam for hemorrhoids unless a healthcare professional specifically recommends it. The FDA-approved hydrocortisone acetate 10% rectal foam indication is ulcerative proctitis, not routine self-treatment of hemorrhoids.

Can I use Entofoam Rectal Foam longer than prescribed?

No. Entofoam Rectal Foam contains a corticosteroid when formulated with hydrocortisone acetate, and prolonged exposure can increase the risk of corticosteroid-related adverse effects. Follow the prescribed duration and attend recommended follow-up visits.