Afenak Plus 100mg/500mg Tablet (Aceclofenac 100mg/Paracetamol 500mg)

Afenak Plus (500/100 mg) Tablet is a combination of Paracetamol and Aceclofenac. It is used to relieve pain in conditions like headache, mild migraines, muscle pain, joint pain, tooth pain, menstrual pain, ankylosing spondylitis (pain due to fusing of bones in the spine), osteoarthritis (pain on movement due to wearing of the protective covering at the ends of the bones) and rheumatoid arthritis (body’s immunity attacks the joints and damages it).

Afenak Plus (500/100 mg) Tablet shows some side effects like nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. It may cause dizziness and sleepiness. Do not drive vehicles or do anything that requires mental focus until you know how this medicine affects you. Do not use this medicine if you are allergic to it.

Afenak Plus (500/100 mg) Tablet can be taken with food, milk, or an antacid to avoid stomach irritation. For the ease of remembering, take it at around the same time every day. Afenak Plus (500/100 mg) Tablet relieves pain and swelling due to arthritic conditions but does not cure it.

Afenak Plus (500/100 mg) Tablet has to be taken with caution if you have peptic ulcers or any medical conditions of your liver and kidney. Afenak Plus (500/100 mg) Tablet may interact with alcohol, and you may see an increase in the side effects such as dizziness, drowsiness, and stomach bleeding.

Afenak Plus (500/100 mg) Tablet may impact or get affected by other medications. Inform your doctor about all your current medications. Do not take other medications that have Paracetamol in them without consulting your doctor. If you are pregnant, planning a pregnancy or are breastfeeding, you should consult your doctor before taking this medication.

Major & minor side effects for Afenak Plus (500/100 mg) Tablet

Allergic skin reaction

Stomach or mouth ulcer

Bloody and cloudy urine

Fatigue

Stomach pain

Constipation

Diarrhoea

Nausea and vomiting

Skin rash

Drowsiness

What is it prescribed for?

Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a condition when your body’s immune system attacks the lining of your small joints. It may also affect other parts of your body. Afenak Plus (500/100 mg) Tablet is used to relieve swelling and pain in the joints due to RA.

Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis. In OA, the flexible tissue at the ends of your bones wears down leading to friction. This causes pain, stiffness, and swelling. Afenak Plus (500/100 mg) Tablet is used to relieve pain and stiffness due to OA.

Ankylosing Spondylitis

Ankylosing Spondylitis is a kind of arthritis that mainly affects the spine causing the small bones of your spinal cord to fuse together. This leads to inflammation, pain and deformity, and a decrease in the flexibility of your spine. Afenak Plus (500/100 mg) Tablet is used to relieve stiffness and pain (especially in the lower back, hip, and pelvis) associated with ankylosing spondylitis.

Mild to Moderate pain

Afenak Plus (500/100 mg) Tablet is used to relieve pain and swelling in conditions like back pain, earache, throat pain, toothache, stomach pain during periods, and muscle injury.

Dysmenorrhoea

Dysmenorrhoea or painful periods is a throbbing, aching cramp or pain that you get in your lower belly just before and during your periods. Most of the women who menstruate may experience this pain for 1-2 days each month. Normally, the pain is mild, but for some women, the pain can be severe. Afenak Plus (500/100 mg) Tablet is used for the treatment of muscle cramps and pain during periods.

Allergy

Avoid taking Afenak Plus (500/100 mg) Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulties, etc.

Kidney failure

Long-term use of high doses of some painkillers may damage normal kidney function. Afenak Plus (500/100 mg) Tablet is not advised for use in individuals with severe kidney problems. People with kidney troubles should consult their doctor before taking this medicine.

Severe liver impairment

Afenak Plus (500/100 mg) Tablet is harmful to your liver when taken for a long period or in high doses. This medicine is not recommended if you have severe liver problems. Consult your doctor before taking this medicine.

Active peptic ulcer

A peptic ulcer is a condition in which sores are developed on the inner lining of your stomach and intestine. Afenak Plus (500/100 mg) Tablet is an NSAID (nonsteroidal anti-inflammatory medicine) that can induce stomach ulcers, bleeding, or holes in the intestine if taken for a long time. This medicine is not recommended if you already have ulcers as it may worsen your condition.

Warnings for special population

Pregnancy

Afenak Plus (500/100 mg) Tablet is not recommended for use in pregnancy. Taking this medication during pregnancy can result in heart defects in your foetus, delay in birth or may increase the risk of bleeding. Consult your doctor before taking this medicine.

Breast-feeding

Afenak Plus (500/100 mg) Tablet may pass into breast milk and can affect your infant. Discuss the benefits and risks with your doctor before taking this medicine.

General warnings

Overdose and/or excessive use

The excessive use of Afenak Plus (500/100 mg) Tablet accidentally or intentionally results in liver damage. Use this medicine as advised by your doctor/pharmacist. Seek emergency medical attention if an overdose is suspected.

Driving or operating machinery

Afenak Plus (500/100 mg) Tablet may cause sleepiness or dizziness in some people. Avoid driving vehicles and operate heavy machines after taking this medicine.

Anaemia

Afenak Plus (500/100 mg) Tablet should be used with caution if you have anaemia due to the increased risk of worsening of your condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on your clinical condition.

Bleeding disorders

Afenak Plus (500/100 mg) Tablet may prolong the blood clotting time and therefore increase the risk of bleeding. Use it cautiously if there are bleeding or clotting defects such as haemophilia (a disorder in which blood does not clot normally), Vitamin K deficiency, and hypoprothrombinemia (deficiency of blood clotting substance Prothrombin).

Missed Dose

If you missed a dose of Afenak Plus (500/100 mg) Tablet take it as soon as you remember. Do not add it with your next dose to make up for a missed dose.

Overdose

Never take more than the prescribed dose. If you suspect that you might have taken an overdose of Afenak Plus (500/100 mg) Tablet, seek immediate medical guidance.

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while treatment with Afenak Plus (500/100 mg) Tablet due to the risk of stomach bleeding.

Interaction with Medicine

Carbamazepine

Lithium

Phenytoin

Sodium Nitrite

Leflunomide

Digoxin

Corticosteroids

Disease interactions

Asthma

You may experience asthma (constriction of airways in your lungs) while taking Afenak Plus (500/100 mg) Tablet. Hence it is not recommended for use if you have asthma, especially when you experienced allergic reactions by using non-steroidal anti-inflammatory medicines (pain killers).

Gastro-Intestinal toxicity

Long term use of Afenak Plus (500/100 mg) Tablet can cause damage to your stomach and intestine. Conditions like bleeding, ulceration and perforation of your stomach or intestinal wall can occur. Any symptom indicating ulceration and bleeding like indigestion, the appearance of dry blood in stools or vomiting of blood should be reported to your doctor immediately.

Heart Disease

Prolonged use of Afenak Plus (500/100 mg) Tablet is known to increase the risk of heart attack and stroke (reduced blood supply to your brain) in individuals with heart problems. Hence caution should be maintained.

Food interactions

Information not available.

Lab interactions

5-HIAA Urine Test

Afenak Plus (500/100 mg) Tablet can interfere with a urine test and may give a false-positive result. It is advised to inform your doctor and lab technician about all your current medicines before undergoing any lab test.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

Take Afenak Plus (500/100 mg) Tablet with food to avoid an upset stomach.

Do not break, crush or chew the tablet.

Take this medicine exactly as prescribed by your doctor.

Do not take this medication for a longer duration than suggested by your doctor.

Consult your doctor before you stop the intake of this medication.

Report any unusual symptoms to your doctor right away.

This medicine may cause dizziness and sleepiness.

Do not drive vehicles or do any task that requires mental focus until you know how Afenak Plus (500/100 mg) Tablet affects you.

Avoid consuming alcohol as it may cause excessive drowsiness, increases the risk of liver damage and stomach bleeding.