Zomet-TH Tablet (Metformin 1000mg)

Medical Description

Zomet Th 1000mg Tab 10’S contains metformin, which belongs to the biguanide group of medicines used to treat type 2 diabetes mellitus (also called known as ‘non-insulin dependent diabetes’).

Uses of Zomet Th 1 G

It is used for type 2 diabetes mellitus (‘non-insulin dependent diabetes’) when diet and exercise have not been able to control your blood glucose levels.

Contraindications of Zomet Th 1 G

If you are allergic to metformin, or any other ingredients of this medicine
If you have liver or severe kidney problems
If you are an alcoholic
If you have uncontrolled diabetes
If you have any heart problems, or if you recently had a heart attack
If you have a severe infection of lung or kidney. Infections can increase the risk for lactic acidosis

Side effects of Zomet Th 1 G

Nausea
Vomiting
Mild diarrhoea
Stomach pain
Altered taste sensations
Loss of appetite
Vitamin B12 deficiency (low level of vitamin B12 in blood)
Skin rash, redness, itching
Lactic acidosis (too much acid in the body)
Abnormal liver function tests and hepatitis

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Other General Warnings

Talk to your doctor if
You suffering from continous diarrhoea, vomiting, loss of body fluids
You experience signs of low blood glucose like dizziness, weakness, rapid heartbeat, sweating, inability to concentrate. Metformin does not usually cause sudden low blood sugar (hypoglycemia). If Metformin is prescribed with other anti-diabetic medications, low blood sugar may occur
You experience muscle pain, stomach pain, vomiting, breathing difficulty, low body temperature. This could be a serious condition known as lactic acidosis
Stop taking Zomet Th 1000mg Tab 10’S for a short time if you have severe vomiting, diarrhea

Mode of Action of Zomet Th 1 G

How Does It Work?
Your pancreas produces a hormone called insulin. Insulin drives glucose (sugar) from the blood to enter inside the cell. Then this glucose is utilized as energy by the cell
If you have diabetes mellitus, your pancreas either does not make enough insulin or your body is unable to use properly the insulin it produces (insulin resistance)
As a result, glucose is not able to enter into the cells and this leads to a high level of glucose in your blood
Zomet Th 1000mg Tab 10’S works by decreasing the amount of glucose absorbed from the intestine, lowering the amount of sugar created by the liver, and facilitating entry of sugar into the cells

Directions for Use of Zomet Th 1 G

Take this medicine with or after a meal to reduce it’s side effects
Consult your doctor for the appropriate dosage of Zomet Th 1000mg Tab 10’S
Take the tablet as a whole with a glass of water.The tablets should not be crushed
Swallow each tablet with a glass of water

Interactions of Zomet Th 1 G

Interactions with other medicines
Medicine used to reduce pain and swelling like ibuprofen, celecoxib
Medicine used to treat asthma like salbutamol or terbutaline
Medicines like furosemide (diuretics)
If you need to take an injection of iodine-containing contrast medium into your bloodstream, for an X-ray or scan, your doctor will ask you to stop taking metformin before or at the time of injection
If you are on medicines that are used to treat pain and inflammation (NSAID and COX-2 inhibitors, such as ibuprofen and celecoxib) for the long term, these can damage your kidneys. Use of such medicines in diabetes should be avoided
Interactions with food items
Absorption of vitamin B12 appears to be reduced during long-term metformin therapy, and annual screening of serum vitamin B12 levels and red blood cell parameters has been recommended
Advisable to have a diabetic diet as advised by your doctor or dietician. This medicine works best along with a good diet and exercise. Exercise is known to decrease insulin resistance

Storage and disposal of Zomet Th 1 G

This medicine should be kept away from excess heat or moisture
Keep away from the reach of children

Dosage of Zomet Th 1 G

Overdose
In the case of overdose, lactic acidosis may occur
Symptoms of lactic acidosis are vomiting, stomache, muscle cramps and difficulty in breathing
You must seek immediate emergency medical care if you suspect an overdose
Missed a Dose
If you miss any dose, take it as soon as you remember with food. However, if it is time for the next dose then skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.