Torsinex Plus Tablet (Spironolactone 25mg / Torasemide 10mg)

Description

Torsinex Plus Tablet is a combination medicine used in the treatment of resistant edema associated with secondary hyperaldosteronism, resistant hypertension, nephrotic syndrome, chronic cardiac failure, and hepatic cirrhosis. This medicine is not recommended for use in patients below 18 years of age.

Side effects

Major & minor side effects for Torsinex Plus Tablet
Stomach pain
Dizziness
Irregular heartbeat
Headache
Skin rash
Breast enlargement in men
Leg cramps
Nausea and Vomiting
Chest pain
Diarrhea
Dry mouth
Loss of appetite
Muscle pain
Sleeplessness
Excessive urination
Constipation

Uses of Torsinex Plus Tablet

What is it prescribed for?
Resistant edema associated with secondary Hyperaldosteronism
This medicine is used in the treatment of resistant edema associated with secondary hyperaldosteronism, a condition where aldosterone is produced excessively due to reduced blood flow to the kidneys.
Congestive Heart Failure
This medicine is used in the treatment of congestive heart failure by preventing water reabsorption.
Resistant Hypertension
This medicine is used in the treatment of resistant hypertension, a condition where the blood pressure remains above 140/90 mmHg despite the concurrent use of three antihypertensive agents of different classes, one of which should be a diuretic.
Hepatic cirrhosis
This medicine is used in the symptomatic treatment of hepatic cirrhosis, a condition characterized by jaundice, ascites, weight loss, swelling of legs, easy bleeding or bruising, etc.
Nephrotic Syndrome
This medicine is used in the symptomatic treatment of nephrotic syndrome, which is a kidney disorder characterized by weight gain due to excess fluid retention, severe swelling around your eyes, ankles, and feet, etc.

Related Product

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to spironolactone, torsemide, or any other inactive ingredients present in the formulation.
Anuria
This medicine is not recommended for use in patients with anuria, a condition where the kidney is unable to produce urine.
Acute kidney failure
This medicine is not recommended for use in patients with acute kidney failure or impaired kidney function due to the increased risk of worsening of the patient’s condition.
Hepatic coma
This medicine is not recommended for use in patients with hepatic coma due to the increased risk of worsening of the patient’s condition.
Hypotension
This medicine is not recommended for use in patients with low blood pressure (hypotension) condition, due to the increased risk of worsening of the patient’s condition.
Eplerenone
This medicine is not recommended for use in patients who are concomitantly taking eplerenone due to the increased risk of worsening of the patient’s condition.
Adrenal insufficiency (Addison’s disease)
This medicine is not recommended for use in patients who are suffering from adrenal insufficiency due to the increased risk of worsening of the patient’s condition.

Warnings

Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
Hyperkalemia
This medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.
Diabetes
This medicine should be used with extreme caution in patients with diabetes mellitus due to the increased risk of severe adverse effects. Close monitoring of blood glucose levels and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Volume depletion and Electrolyte imbalance
This medicine may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Use in elderly patients
This medicine should be used with caution in elderly patients due to the increased risk of severe adverse effects. Appropriate dose adjustments may be necessary based on the clinical condition.
Hearing problem
Use of this medicine may increase the risk of developing a hearing problem in some patients. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Driving or operating machinery
Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery during treatment with this medicine if you experience any of these symptoms.
Use in Children
This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

General Instructions
Take this medicine as advised by your doctor. Do not take in larger amounts than prescribed. It is advised to take this medicine at daytime to prevent sleep disturbance. Drink an adequate amount of water. Close monitoring of kidney function and electrolytes levels is necessary during treatment with this medicine. Report any undesired side effects to the doctor. Do not stop the use of this medicine without consulting your doctor.