Spexib Capsule (Ceritinib 150mg)

Description

Spexib Capsule is used in the treatment of Non-small cell lung cancer (NSCLC), which is a type of cancer that affects the lungs. This medicine is not recommended for use in patients below 18 years of age.

Side effects

Major & minor side effects for Spexib Capsule
Nausea and vomiting
Diarrhea
Loss of appetite
Abdominal pain
Skin Rash
Weight loss
Fever
Unusual tiredness and weakness
Blurred vision

Uses of Spexib Capsule

What is it prescribed for?
Non-Small Cell Lung Cancer
This medicine is used as a first-line treatment for Non-small cell lung cancer in patients with anaplastic lymphoma kinase (ALK)-positive.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to Ceritinib or any other inactive ingredients present along with it.

Warnings

Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition
General warnings
Liver Disease
Use of this medicine should be done with caution in patients with liver diseases due to the increased risk of liver toxicity. Close monitoring of liver function is recommended for patients on treatment with this medicine. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Lung toxicity
Use of this medicine should be done with caution since it may increase the risk of Interstitial Lung Disease (ILD) with lung infiltration, pneumonitis, acute respiratory distress syndrome, allergic alveolitis, etc especially in patients with lung disorders. Management of lung toxicities may include symptomatic therapies, temporary treatment discontinuation and/or dose modification, or in severe or persistent cases, permanent discontinuation of the treatment. Report any symptoms such as difficulty in breathing, cough, fever, etc to the doctor immediately. An alternative treatment option should be considered in some cases based on the clinical condition.
Heart rhythm disorders
Use of this medicine may cause cardiac rhythm dysfunctions. Close monitoring of cardiac function, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. Discontinuation of the medicine is recommended in case of development of severe cardiac adverse effects.
Increased blood glucose level
Use of this medicine is associated with an increased risk of elevated blood glucose levels. Close monitoring of blood sugar levels, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Pancreatitis
Use of this medicine may increase the risk of pancreatitis in some patients. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Gastrointestinal adverse reactions
Use of this medicine should be done with caution in patients with gastrointestinal disorders due to the increased risk of severe gastrointestinal toxicity. Close monitoring, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Use in Children
This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.
Driving or Operating machinery
Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Contraception
Use of this medicine may increase the risk of harm to the unborn baby in pregnant women. Effective contraception is advised for women with the childbearing potential to avoid such risks. Birth controls should be administered while receiving this medicine and for 6 months post-therapy to prevent the pregnancy.

Dosage

Missed Dose
Take the missed dose as soon as you remember. If it is almost 12 hours due for the next scheduled dose, then the missed dose can be skipped. Contact your doctor for further instructions if you miss more than one scheduled dose of this medicine.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

General Instructions
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Take this medicine with food at the same time daily. You may require frequent blood tests, cardiac tests, and liver function tests while taking this medicine. You may also require frequent followups with your doctor to check the progress of treatment. Do not stop the use of this medicine without consulting your doctor.