Palido-OD 3 Tablet (Paliperidone 3mg)

INTRODUCTION

PALIDO OD 3MG contain paliperidone which belongs to a group of medicine called antipsychotics. It is used to treat schizophrenia in adults and in adolescents aged 15 years and older and also used to treat schizoaffective disorder in adults. Schizophrenia is a disorder characterised by symptoms such as hearing seeing or sensing thing that are not present, unusual suspiciousness, becoming withdrawn, incoherent speech, and behaviour and emotional changes. People with this disorder can also feel depressed, anxious, guilty, or tensed. In schizoaffective disorder, a person experiences combination symptoms of both schizophrenia and mood disorder symptoms such as feeling very high or sad, distracted, talking more than normal, losing interest in everyday activity, sleeping too much or too little, eating too much or too little, and getting suicidal thoughts.

Always take PALIDO OD 3MG exactly as your doctor has told you. This medicine is not for use in children and adolescents under 15 years for the treatment of schizophrenia and not under 18 years for the treatment of schizoaffective disorder. Do not drive or operate any machine while taking this medicine since it may cause dizziness and vision problems. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF PALIDO OD 3MG

Treat schizophrenia and schizoaffective disorder

HOW PALIDO OD 3MG WORKS

PALIDO OD 3MG works by affecting the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts and behavior.

DIRECTIONS FOR USE

Always take PALIDO OD 3MG exactly as your doctor has told you. This medicine must be taken every morning with breakfast or without breakfast. Try to take this medicine at the same time each day. Do not alternate between taking this medicine with breakfast one day and without having breakfast the next day. It should be swallowed whole with water. Do not crush or chew the medicine.

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SIDE EFFECTS OF PALIDO OD 3MG

SERIOUS
Blood clots in the veins
Dementia
Muscle stiffness, sweating or a lowered level of consciousness (Neuroleptic Malignant Syndrome)
Prolonged or painful erection (priapism)
Involuntary rhythmic movements of the tongue, mouth, and face
Severe allergic reactions such as fever, swollen mouth, face, lip or tongue, shortness of breath, itching, skin rash and sometimes drop in blood pressure
COMMON
Parkinsonism
Restlessness
Feeling sleepy or less alert
Headache
Infection of the chest (bronchitis)
Urinary tract infection
Weight gain, increased appetite, weight loss, decreased appetite
Mania, irritability, depression, anxiety
Dystonia, dyskinesia
Dizziness
Tremor
Blurry vision
Slow or rapid heart rate
Low blood pressure upon standing, high blood pressure
Abdominal pain, abdominal discomfort
Dry mouth, toothache
Itching, rash
Bone or muscle ache, back pain, joint pain
Loss of menstrual periods
Fever, weakness, fatigue (tiredness)
RARE
Eye infection
Fungal infection of the nails
Infection of the skin
Low numbers of a certain type of white blood cell, increase in eosinophils (a type of white blood cell) in your blood
Sugar in the urine
Inappropriate secretion of a hormone
Uncontrolled diabetes
Excessive intake of water, low blood sugar, excessive drinking of water, increased cholesterol in your blood

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Abdominal pain:

Try to rest and relax. Eat and drink slowly or have smaller and frequent meals. Applying heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Constipation:

Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Diarrhoea:

Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.

WARNING & PRECAUTIONS

PREGNANCY
PALIDO OD 3MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING
PALIDO OD 3MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES
Do not drive or operate any machine while taking this medicine since it may cause dizziness and vision problems.

ALCOHOL
Consumption of alcohol is not recommended during treatment with PALIDO OD 3MG.

KIDNEY
PALIDO OD 3MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER
PALIDO OD 3MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY
Do not take PALIDO OD 3MG if you are allergic (hypersensitive) to paliperidone or any other ingredients in this medicine.

HEART DISEASE
PALIDO OD 3MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.

OTHERS

Tell your doctor if you have or had a condition such as,

Parkinson’s disease
High temperature and muscle stiffness (Neuroleptic Malignant Syndrome)
Abnormal movements of the tongue or face (Tardive dyskinesia)
Low levels of white blood cells in the past
Diabetic or prone to diabetes
Breast cancer or a tumour in the pituitary gland in your brain
Low blood pressure when you stand up or sit up suddenly
Epilepsy
Prolonged and/or painful erection
Problems with controlling core body temperature or overheating
An abnormally high level of the hormone prolactin in your blood or have a possible prolactin-dependent tumour
Family history of blood clots

INTERACTIONS

Talk to your doctor if you are taking,

Heart medicines (used to control heart rhythm)
Some other types of medicines such as antihistamines, antimalarials, or other antipsychotics
Medicines for lower blood pressure
Levodopa (used to treat parkinson’s disease and restless legs syndrome)
Metoclopramide
Valproate
Oral risperidone
Psychostimulants such as methylphenidate (increase the activity of the central nervous system)