Onglyza 5mg Tablet (Saxagliptin 5mg)

Onglyza 5 mg Tablet 14’s contains saxagliptin which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in the treatment of type 2 diabetes in adults. Onglyza 5 mg Tablet 14’s is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body’s response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.

Onglyza 5 mg Tablet 14’s work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Onglyza 5 mg Tablet 14’s should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis.

Onglyza 5 mg Tablet 14’s should be taken with food or empty stomach. However, it should be taken at the same time of the day each time for best results. For better advice, your doctor will decide, what dose should be taken and it can change timely depending upon your condition. The most common side effect of Onglyza 5 mg Tablet 14’s are hypoglycemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold) and headache.

Onglyza 5 mg Tablet 14’s should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Onglyza 5 mg Tablet 14’s abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Onglyza 5 mg Tablet 14’s should not be taken if you have severe kidney or liver disease. Please inform your doctor if you have any heart disease, is or planning to get pregnant or breastfeeding.

Prolonged intake of Onglyza 5 mg Tablet 14’s may cause acute pancreatitis (swollen pancreas), and critical kidney problem. Increased risk of hypoglycemia (low blood sugar level) can occur when Onglyza 5 mg Tablet 14’s is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Onglyza 5 mg Tablet 14’s. Severe allergic reactions might occur in some patients taking Onglyza 5 mg Tablet 14’s like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions including Stevens-Johnson syndrome. Safety and efficacy of Onglyza 5 mg Tablet 14’s in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Onglyza 5 mg Tablet 14’s should be closely monitored as severe drug interaction has been observed.

• Type 2 diabetes (non insulin dependent  diabetes).

Onglyza 5 mg Tablet 14’s work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Thus, Onglyza 5 mg Tablet 14’s plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.

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Swallow the tablet whole with a glass of water at the start of a meal or slightly before. Space the doses evenly during the day, at least 4 hours apart. Do not chew or crush it.

Store in a cool and dry place away from sunlight

Most of the side effects of Onglyza 5 mg Tablet 14’s do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Some common side effect of Onglyza 5 mg Tablet 14’s are hypoglycaemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold) and headache. But these would be temporary and may be relieved after some time. However, if you still have discomfort speak with the doctor.