Nemdaa 5 Tablet (Memantine 5mg)

INTRODUCTION

NEMDAA 5MG contain memantine which belongs to a group of medicine called NMDA receptor antagonists. It is used for the treatment of patients with moderate to severe Alzheimer’s disease. Alzheimer’s disease is a progressive disease that destroy memory and mental functions. Memory loss in Alzheimer’s disease is due to disturbance of message signals in the brain. The brain contains N-methyl-D-aspartate (NMDA)-receptor that are involved in transmitting nerve signals important in learning and memory. This medicine acts on these NMDA-receptors improving the transmission of nerve signals and the memory.

Glutamate is a chemical that helps to send messages between nerve cells in the brain. In Alzheimer’s disease nerve cells are damaged resulting in the production of too much of glutamate. This causes more damage to the nerve cells. Memantine protects nerve cells by blocking the effects of excess glutamate without disturbing the normal transmission of nerve signals.

The common side effects are headache, sleepiness, constipation, elevated liver function tests, dizziness, balance disorders, shortness of breath, high blood pressure, hypersensitivity. This medicine is strictly not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF NEMDAA 5MG

Treat patients with moderate to severe Alzheimer’s disease

HOW NEMDAA 5MG WORKS

Glutamate is a chemical that helps to send messages between nerve cells in the brain. In Alzheimer’s disease nerve cells are damaged resulting in the production of too much of glutamate. This causes more damage to the nerve cells. Memantine protects nerve cells by blocking the effects of excess glutamate without disturbing the normal transmission of nerve signals.

DIRECTIONS FOR USE

Always take NEMDAA 5MG exactly as your doctor has told you. This medicine must be taken with or without food. Try to take at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine. The recommended dose is one tablet once a day.

SIDE EFFECTS OF NEMDAA 5MG

COMMON
Headache
Sleepiness
Constipation
Elevated liver function tests
Dizziness
Balance disorders
Shortness of breath
High blood pressure
Hypersensitivity

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HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Sleepiness:

Get up and move around to feel awake. Take a nap to take the edge off the sleepiness. Give your eyes a break to avoid weakness.

Constipation:

Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

WARNING & PRECAUTIONS

PREGNANCY
NEMDAA 5MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING
NEMDAA 5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES
Your doctor will tell you whether your illness allows you to drive and to use machines safely. Also NEMDAA 5MG may change your reactivity, making driving or operating machinery inappropriate.

ALCOHOL
Consumption of alcohol is not recommended during treatment with NEMDAA 5MG.

KIDNEY
NEMDAA 5MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.

LIVER

NEMDAA 5MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY
Do not take NEMDAA 5MG if you are allergic (hypersensitive) to memantine or any other ingredients in this medicine.

HEART DISEASE
NEMDAA 5MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.

OTHERS

Tell your doctor if you have or had conditions such as,

Have a history of epileptic seizures
Suffering from high blood pressure
Severe infections of the urinary tract

INTERACTIONS

Talk to your doctor if you are taking,

Amantadine (used to treat Parkinson’s disease)
Ketamine (used as an anaesthetic)
Dextromethorphan (used to treat cough)
Dantrolene, baclofen
Cimetidine, ranitidine, procainamide, quinidine, quinine, nicotine
Hydrochlorothiazide
Anticholinergics (used to treat movement disorder or intestinal cramps)
Anticonvulsants (used to prevent and relieve seizures)
Barbiturates (used to induce sleep)
Dopaminergic agonists such as L-dopa, bromocriptine
Neuroleptics (used to treat mental disorders)
Oral anticoagulants