Neksium D 40 Capsule (Domperidone 30mg / Esomeprazole 40mg)

Do not take Neksium D 40 Capsule 10’s if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, and heart problems. Inform your doctor before taking Neksium D 40 Capsule 10’s if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Neksium D 40 Capsule 10’s. On long-term treatment, Neksium D 40 Capsule 10’s may cause low magnesium levels, vitamin B12 levels, and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Do not take Neksium D 40 Capsule 10’s if you are pregnant or breastfeeding unless prescribed by the doctor. Neksium D 40 Capsule 10’s may cause dizziness, so drive only if you are alert. Neksium D 40 Capsule 10’s should not be given to children as safety have not been established. Avoid consuming alcohol along with Neksium D 40 Capsule 10’s as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Neksium D 40 Capsule 10’s is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

DRUG-DRUG INTERACTIONS: Neksium D 40 Capsule 10’s may have interaction with anti-HIV (atazanavir, nelfinavir, saquinavir, ritonavir), blood thinner (clopidogrel, warfarin), anti-fungal (ketoconazole, itraconazole, voriconazole, fluconazole), anti-cancer (erlotinib, toremifene, vandetanib, vincamine), benzodiazepine (diazepam), anti-convulsant (phenytoin), anti-platelet (Cilostazol), antacid (cisapride, dolasetron, prucalopride), immunosuppressant (tacrolimus), anti-TB (rifampicin), antibiotics (Erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), a drug used to treat hypothyroidism (levothyroxine), anti-rheumatoid (methotrexate), anti-depressant (citalopram, escitalopram), cardiac glycoside (digoxin), anti-malarial (halofantrine), anti-psychotic (haloperidol, pimozide, sertindole), anti-allergy ( mequitazin, mizolastine), anti-arrhythmic (amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol), anti-hypertensives (diltiazem, verapamil).

FOOD-DRUG INTERACTIONS: Neksium D 40 Capsule 10’s may have interaction with St.John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption as alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

DRUG-DISEASE INTERACTION: Neksium D 40 Capsule 10’s may have interactions with Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, and heart problems.