Mixtard 30 HM 100IU/ml Penfill (Insulin Isophane/NPH 70% / Human Insulin/Soluble Insulin 30%)

Medical Description

Mixtard 30hm Penfill Injection 3ml contains insulin which belongs to class of Insulins and analogues (synthetic human hormones).

Uses of Mixtard Hm Penfill 100 IU/ML

Treatment of diabetes mellitus.

Contraindications of Mixtard Hm Penfill 100 IU/ML

If you are allergic to insulin or any of the ingredients of this medicine
If you are suffering from hypoglycemia (low blood sugar level).

Side effects of Mixtard Hm Penfill 100 IU/ML

Low blood sugar (Hypoglycaemia)
Lightheadedness
Dizziness
Anxiety
Nervousness
Tiredness
Feeling hungry
Visual disturbances
Headache
Shaking
Sweating
Pale skin
Skin rashes
Pain, redness, swelling at injection site.

Other General Warnings

Talk to your doctor if
You have recurrent low blood sugar levels
Be very careful about symptoms of low blood sugar like sweating, anxiety, fast heartbeat, headache, intense hunger, restlessness, dizziness, irritability. If you experience these, immediately have sugar (Do not consume artificial sweeteners). Eat something as soon as possible. Do not take insulin in such a scenario. If still the symptoms persists, seek emergency medical help
You have frequent fever and infections
You have diseases related to liver and kidney
You have thyroid disorders
You are switching to different insulin medicine brand
You have pain, itching and swelling at the injection site, you should continuously change the site of injection
Avoid doing heavy exercise
You are planning to change your diet preferences
You should always carry sugar candy with you
You are taking insulin but not taking adequate meals, your blood glucose can drop drastically.

Mode of Action of Mixtard Hm Penfill 100 IU/ML

How Does It Work?
Insulin is a crucial hormone that allows entry of blood glucose into each cell of the body. Inside the cell, this glucose is used as fuel.
In type 1 diabetes mellitus, the body fails to produce adequate insulin and this leads to glucose accumulating in the blood and causes high blood glucose.
This medicine lowers blood sugars by stimulating glucose uptake by cells, tissue and muscles, especially by skeletal muscles and fat and by inhibiting glucose production by the liver.

Directions for Use of Mixtard Hm Penfill 100 IU/ML

Take this injection as per the technique suggested by your doctor or nurse
This injection is to be taken under the skin of the thigh or upper arm or abdomen
Do not take this injection in vein or in muscles
Pull a skin, fold up to take this injection
Wait for at least 6 sec before removing the needle from the injection site
Always rotate the site of injection, do not take concurrent injections at the same site.

Interactions of Mixtard Hm Penfill 100 IU/ML

Interactions with other medicines
You may have symptoms of low blood sugar if you are taking other medicines for diabetes, depression (fluoxetine), medicines for fever and pain (salicylates), ramipril, lisinopril
You may have high blood sugar if you are taking oral contraceptives, thiazide, steroids, thyroxine, medicines used to treat severe diarrhoea and abnormal growth of body organs like octreotide, lanreotide
If you are taking a medicine pioglitazone to treat diabetes, be cautious, as some cases of heart attack and heart failure have been reported
Some medicines block your body’s response to low blood sugar, so you may not experience symptoms like headache, hunger pangs, sweating, anxiety when your blood sugar drops. This can lead to a serious fall in blood sugar. Inform your doctor if you are on medicines like Betablockers (Metoprolol, Propranolol, Atenolol), Clonidine, Guanethidine and Reserpine.
Interactions with food items
This medicine is to be taken 15 mins before meals or after meals
Maintaining a constant meal pattern is advisable when you are taking insulin
Avoid skipping or delaying meals when you are taking insulin

Storage and disposal of Mixtard Hm Penfill 100 IU/ML

Store between 2°C to 8°C in the refrigerator
Do not freeze it
Keep it out of the reach of children
Do not open the carton of vials to protect it from light
Any unused portion should not be stored and should be appropriately discarded.

Dosage of Mixtard Hm Penfill 100 IU/ML

Overdose
Excess insulin will lead to low blood sugar levels, called hypoglycemia. You may experience symptoms like dizziness, fainting, sweating and tremors.
If you have the blood glucometer with you, test immediately and confirm blood glucose levels.
Whether or not you test your levels, it is important to take some glucose water/juice/eat sugar or chocolates immediately and then rush to your doctor.
Missed a Dose
Missed dose may lead to high blood sugar levels which can cause symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, fruity smell from breath, etc.
If you missed any dose of medicine take it as soon as you remember. If it’s time for your next dose then skip the missed dose and continue with your regular dose schedule.
Do not take a double dose of medicine to compensate the missed one as taking double dose can cause a drastic fall in blood glucose which can be dangerous.