ME-PR Capsule (Methylcobalamin/Pregabalin 75mg)

ME-PR Capsule medicine consisting of Mecobalamin and Pregabalin. It is used for the treatment of peripheral neuropathy (weakness, numbness and pain from nerve damage, usually in the hands and feet) in adults. ME-PR Capsule relieves pain by inactivating certain chemical messengers in the brain and repairing damaged nerve cells and fibres.

ME-PR Capsule can cause side effects such as dizziness, drowsiness, tiredness and uncoordinated body movements. These side effects are temporary and can usually resolve with time. Consult your doctor if these effects persist for a long time. Keep a check of your mood and behaviour as this medicine can cause mood and behaviour changes like depression and suicidal tendencies. In such cases, contact your doctor immediately.

ME-PR Capsule is recommended to be taken with or without food. To maintain constant levels of this medicine, take it at the same time every day. Use this medicine in the dose and duration as prescribed by your doctor. It is recommended that you should not stop taking this medicine without consulting your doctor. If stopped abruptly, you might experience withdrawal symptoms like anxiety, fatigue, sweating, vomiting, depression, seizures, and hallucinations.

ME-PR Capsule is not recommended for use in children less than 18 years of age. Inform your doctor if you have medical complications associated with kidney or liver conditions as ME PR Capsule may worsen these conditions. ME PR Capsule is not recommended if you are pregnant, or are breastfeeding. Your doctor may prescribe this medicine only when the benefits outweigh the risks, or another suitable medicine may be prescribed.

ME PR Capsule may cause drowsiness. Do not consume alcohol while using ME PR Capsule, as it can lead to excessive drowsiness. Be careful when you rise from a sitting or lying position, as this medicine may cause dizziness.

Major & minor side effects for ME-PR Capsule

Difficulty in breathing

Chest tightness

Chills

Severe diarrhoea

Swelling of face, lips, eyelids, tongue, hands and feet

Blurred or double vision

Dizziness

Headache

Fever

Anxiety and nervousness

Slurred speech

Trouble sleeping

Loss of bladder control

Burning, numbness, tingling in the arms and feet

Nausea and vomiting

Loss of appetite

Uncoordinated body movements

Drowsiness

Related Product

What is it prescribed for?

Peripheral neuropathy

ME PR Capsule is used for the treatment of peripheral neuropathy (pain due to nerve damage).

Allergy

Avoid receiving ME-PR Capsule if you have a known allergy to this medicine. Seek medical attention if you experience any undesirable effects such as skin rash, hives (itchy, raised scars that are found on the skin), swelling (of face, lips, tongue), etc.

Leber’s Disease

Leber’s Disease is a condition inherited from your mother. It causes you to lose your eyesight, starting with painless blurriness. ME PR Capsule is not recommended for use in patients suffering from Leber’s Disease, a rare genetic disorder.

Warnings for special population

Pregnancy

ME-PR Capsule is not recommended for use in pregnancy as it may harm your foetus. Consult your doctor before taking this medicine.

Breast-feeding

ME PR Capsule is not recommended for use in breastfeeding as it may pass into breastmilk and harm your baby. Consult your doctor before taking this medicine.

General warnings

Kidney disease and dialysis

ME PR Capsule should be used with extreme caution if you have an impaired kidney function. Your doctor will advise kidney tests while taking this medicine.  Appropriate dose adjustments or replacement with a suitable alternative may be required based on your condition and therapeutic response.

Suicidal tendencies

ME PR Capsule may cause suicidal ideation (suicidal thoughts). Caution should be maintained while using this medicine if you have any psychological condition. Your doctor may monitor you closely for any mood and behavioural changes. Replacement with a suitable alternative should be considered based on your clinical condition.

Driving or operating machines

ME PR Capsule may increase your risk of experiencing drowsiness, dizziness, difficulty in concentrating, etc. Hence, activities that need a high level of mental attention like driving vehicles or operating heavy machines should be avoided.

Withdrawal symptoms

Do not stop using ME PR Capsule abruptly. The risk of withdrawal symptoms is significantly high if it is discontinued suddenly. Complete the treatment with this medicine as prescribed by your doctor.

Oedema

ME-PR Capsule may increase the risk of oedema. Hence, it should be used with caution if you have any condition of fluid retention. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition.

Heart block

ME PR Capsule may cause heart rhythm abnormalities which could result in a blockage and associated complications. It should be used with caution if you have any condition related to the heart and blood vessels. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition.

Potential for abuse

ME PR Capsule may cause dependence, especially in chronic alcohol users or in people who have used other habit-forming agents in the past. Report the past use of alcohol or other drugs to your doctor before receiving this medicine. Your doctor may consider replacing it with a suitable alternative based on your clinical condition.

Rhabdomyolysis

ME-PR Capsule has been associated with rare cases of muscle breakdown conditions that affect kidneys. You should report any instance of muscle pain, weakness, the presence of dark reddish colouration of urine, etc., to your doctor on priority. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition.

Use in elderly

ME PR Capsule should be used with caution in elderly. Appropriate dose adjustments or replacement with a suitable alternative may be required in elderly people.

Gastrointestinal surgery

ME PR Capsule should be used with caution in people who have had recent surgery of the stomach or intestines, as they may have reduced absorption of this medicine.

Use in children

ME PR Capsule is not recommended for use in children less than 18 years of age since the safety and effectiveness of this medicine are not studied.

Missed Dose

Take the missed dose of ME-PR Capsule as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to compensate for the missed one.

Overdose

Seek emergency medical treatment or contact your doctor if you suspect that you might have taken an overdose of ME PR Capsule.

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Alcohol should not be consumed while using ME PR Capsule since it may increase the risk of drowsiness, dizziness, and difficulty concentrating.

Interaction with Medicine

Chloramphenicol

Lorazepam

Omeprazole

Ranitidine

Buprenorphine

Oxycodone

Propoxyphene

Hypoglycemic agents

ACE inhibitors

Disease interactions

Angioedema

ME PR Capsule should be used with caution if you have a known history of angioedema (painless swelling under the skin, triggered by an allergy to animal dander, pollen, drugs, venom, food or medication) since it may worsen your condition. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition and therapeutic response.

Food interactions

Information not available.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

Take ME-PR Capsule with or without food as instructed by your doctor. Do not take in larger or smaller amounts than prescribed. Ensure that the course of treatment is completed and do not stop without consulting your doctor since this may cause severe withdrawal symptoms.

Consult the doctor if you developed any unusual mood changes, depression, and suicidal thoughts while taking this medicine.

Keep the medicine away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.