Macprox DP 250 Tablet (Naproxen 250mg / Domperidone 10mg)

Description

Macprox DP 250 Tablet is a combination medicine that may be used to treat relieve pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, spondylitis, dysmenorrhea, etc. It is also used to relieve symptoms of migraine headaches. This medicine is not recommended for use in patients who weigh less than 35 kg.

Side effects

Major & minor side effects for Macprox DP 250 Tablet
Swelling of face, lips, eyelids, tongue, hands and feet
Difficulty in breathing
Skin rash
Convulsions (seizures)
Heart rhythm disorders
Breast pain and tenderness
Dry mouth
Decreased sexual urge
Breast like growth in men
Stomach pain
Constipation
Dizziness
Hearing impairment
Change in appetite
Irregular menstrual periods

Uses of Macprox DP 250 Tablet

What is it prescribed for?
Rheumatoid Arthritis
This medicine is used to treat symptoms like swelling, pain, and stiffness of joints associated with Rheumatoid Arthritis.
Osteoarthritis
This medicine is used to treat symptoms like tender and painful joints associated with Osteoarthritis.
Ankylosing Spondylitis
This medicine is used to treat symptoms like stiffness and pain associated with Ankylosing Spondylitis.
Dysmenorrhea
This medicine is used to relieve excessive pain and cramps during menstruation.
Migraine
This medicine is used to relieve symptoms of migraine headaches.

Related Product

When not to use?

Tumor of Pituitary gland
This medicine is not recommended for use in patients having a tumor of the pituitary gland due to the increased risk of worsening of the patient’s condition.
Heart diseases
This medicine is not recommended for use in patients having an active heart disease like Congestive Heart Failure or who are suffering from prolonged QT intervals due to the increased risk of worsening of the patient’s condition.
Allergy
This medicine is not recommended for use in patients with a known allergy to naproxen, domperidone, or any other inactive ingredients present in the formulation.
Asthma
This medicine is not recommended for use in patients with asthma caused by aspirin or other non-steroidal anti-inflammatory drugs due to the increased risk of worsening of the patient’s condition.
Gastrointestinal disorders
This medicine is not recommended for use in patients with gastrointestinal bleeding disorders or active peptic ulcers due to the increased risk of worsening of the patient’s condition.
Moderate to Severe Hepatic Impairment
This medicine is not recommended for use in patients with moderate to severe liver impairment due to the increased risk of worsening of the patient’s condition.

Warnings

Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
Other medicines
Macprox DP 250 Tablet may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.
Effect on heart
Use of this medicine may affect the functioning of the heart, especially in the elderly and people having an active condition like rhythm disorders. Regular monitoring of the cardiac function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Electrolyte imbalance
This medicine should be used with extreme caution in patients who are suffering from acute or long-term electrolyte imbalance in the body due to the increased risk of worsening the condition. Regular monitoring of the electrolyte levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Skin rash
This medicine may cause fatal skin allergies without any warnings. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. The treatment should be discontinued if these symptoms appear.
Use in Elderly
This medicine should be used with caution in the elderly population due to an increase in the risk of undesired side effects. Close monitoring of kidney function and symptoms of bleeding is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Prolactin imbalance
This medicine may cause an imbalance in the levels of prolactin resulting in disturbances in the menstrual cycle in women. Prolonged use of this medicine can also result in breast like growth in men.
Driving or Operating machinery
Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Use in Children
This medicine is not recommended for use in patients below 2 years of age and who are weighing less than 35 kg since the safety and efficacy of use are not clinically established.

Dosage

Missed Dose
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

General Instructions

Take this medicine exactly advised by your doctor. You can take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.