Lupinem 500mg Injection (Imipenem 500mg / Cilastatin 500mg)

Lupinem 500 mg Injection is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach and female reproductive organs. Lupinem 500 mg Injection may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. Lupinem 500 mg Injection does not work against infections caused by the virus, including cold and flu.

Lupinem 500 mg Injection is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Lupinem 500 mg Injection helps to treat bacterial infections.

Lupinem 500 mg Injection will be administered by a healthcare professional; do not self-administer. The dose and duration of Lupinem 500 mg Injection can vary depending upon your condition, and the severity of the infection. In some cases, you may experience certain common side effects such as nausea, vomiting, diarrhoea, swelling, and redness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult your doctor before taking Lupinem 500 mg Injection if you are pregnant or breastfeeding. Lupinem 500 mg Injection may cause dizziness, so drive with caution. Avoid alcohol consumption while taking Lupinem 500 mg Injection as it might cause increased dizziness and sleepiness. Lupinem 500 mg Injection should not be given to children below one year or those who weigh below 30kg with kidney problems. Lupinem 500 mg Injection is not recommended in paediatric patients with CNS infections due to the risk of seizures. Keep your doctor informed about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Severe bacterial infections

Lupinem 500 mg Injection is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Lupinem 500 mg Injection is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach, and female reproductive organs. Lupinem 500 mg Injection may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Lupinem 500 mg Injection helps to treat bacterial infections. Imipenem is a broad-spectrum antibiotic that is effective against a wide range of aerobic and anaerobic bacteria.

Lupinem 500 mg Injection will be administered by a healthcare professional; do not self-administer. Depending upon your condition and severity of the infection, your doctor will decide the dose and duration of Lupinem 500 mg Injection.

Store in a cool and dry place away from sunlight

• Nausea
• Vomiting
• Diarrhoea
• Swelling
• Redness at the site of injection