Listril 2.5 Tablet (Lisinopril 2.5mg)

INTRODUCTION

LISTRIL 2.5MG contains Lisinopril which belongs to a group of medicines called Angiotensin converting enzyme (ACE) inhibitors. ACE inhibitors lowers blood pressure by widening blood vessels which allows the blood to flow more easily and reduces the effort needed to pump blood around the body. It is used to treat high blood pressure (hypertension), heart failure, kidney problems in diabetic patients with high blood pressure and also used if you have recently had a heart attack (myocardial infarction).

Lisinopril is long-acting angiotensin converting enzyme inhibitor. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. The inhibition of ACE results in reducing stress on the heart and relaxes blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

Always take this LISTRIL 2.5MG exactly as directed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems, pregnant women and breastfeeding mothers. It is not suitable for use in children below 6 years of age. The common side effects are dizziness, headache, cough, di

arrhoea and vomiting.

USES OF LISTRIL 2.5MG

High blood pressure (hypertension)
Heart failure

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HOW LISTRIL 2.5MG WORKS

LISTRIL 2.5MG is long-acting angiotensin converting enzyme inhibitor. ACE is a peptidyl dipeptidase that catalyzes the conversion of angiotensin I to the vasoconstrictor substance, angiotensin II which also stimulates aldosterone secretion by the adrenal cortex. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

DIRECTIONS FOR USE

Always take this LISTRIL 2.5MG exactly as your doctor has told you. Swallow the medicine as a whole, with a glass of water. Do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF LISTRIL 2.5MG

COMMON
Dizziness
Headache
Cough
Diarrhoea
Vomiting
Kidney problems
RARE
Swelling of the hands, face, lips, tongue and/or throat which cause difficulty breathing or swallowing
Severe itching of the skin
Produces little, cloudy urine or blood in the urine with lower back pain, feeling or being sick or swelling in legs, ankles or feet

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

Cough:

Drink more fluids and suck hard candies which helps to ease dry cough and soothe an irritated throat.

WARNING & PRECAUTIONS

PREGNANCY
LISTRIL 2.5MG is not recommended in early pregnancy, and must not be taken when more than 3 months pregnant, as it may cause serious harm to your baby if it is used after the third month of pregnancy.

BREASTFEEDING
LISTRIL 2.5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES
Do not drive or operate machinery while taking this medicine, since it may cause dizziness or tiredness.

KIDNEY
LISTRIL 2.5MG is not recommended in patients with active kidney diseases. Discuss the risks and benefits with your doctor.

LIVER
LISTRIL 2.5MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.

ALLERGY
Do not take if you are allergic (hypersensitive) to Lisinopril.

HEART DISEASE
LISTRIL 2.5MG should be used with caution in patients suffering from abnormal functioning of the heart, narrowing (stenosis) or hardening of the arteries of heart or an enlarged heart or any other active heart diseases. Consult your doctor for advice.

OTHERS

Inform your doctor if you have or had,

Severe allergic reaction
Diabetes
Low blood pressure (hypotension)
Scleroderma
SLE or lupus
High levels of potassium in blood (hyperkalaemia)

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

Racecadotril (used to treat diarrhoea)
Ciclosporin, temsirolimus, sirolimus, everolimus (used to prevent organ transplant rejection)
Vildagliptin, gliclazide and metformin (used to treat diabetes)
Sacubitril/ valsartan, telmisartan, irbesartan (used to treat a type of long-term heart failure)
Heparin (used to thin blood clots)
Amiloride, triamterene, spironolactone
Trimethoprim and cotrimoxazole
Lithium, amitriptyline (used to treat mental illnesses)
Indomethacin, acetylsalicylic acid, celecoxib, rofecoxib (used to treat pain and inflammation)
Sodium aurothiomalate (used to treat arthritis)
Glyceryl trinitrate (help to lower blood pressure)
Ephedrine or pseudoephedrine (used to treat cough or cold)
Lidocaine (anaesthetic medicine)
Allopurinol (used to treat gout)
Procainamide (used to treat abnormal heart rhythms)