Iverscab 12mg Tablet (Ivermectin 12mg)

INTRODUCTION

IVERSCAB 12MG contains Ivermectin which belongs to the group of medicines called anthelmintics. It is used to treat various parasitic infections such as onchocerciasis, intestinal strongyloidiasis, filarial worm infestations (e.g. lymphatic filariasis or microfilaraemia), hookworm infestations, scabies, pediculosis (head lice) and helminthiasis (such as Ascariasis (roundworms), Trichuriasis (whipworm) and Enterobiasis (Pinworm)).

Onchocerciasis (also known as river blindness) is a parasitic (worm) infection mainly affecting the skin, lymph nodes and eyes. It is characterized by skin rash, itching, bumps under the skin, enlarged glands in the neck, armpits and groin, painful eyes or blindness. Intestinal strongyloidiasis (threadworm infection) is a parasitic infection mainly affecting the skin and the intestines. It is characterized by skin rash, itching, stomach pain, vomiting and diarrhea. Lymphatic filariasis is a worm infection that affects the lymph nodes and lymph vessels, while microfilaraemia is a filarial infection affecting the blood.

Scabies is a communicable skin infection that can spread from person to person via direct skin contact, including sexual contact and contact via exposure to the clothing or furnishings used by the infected person. It is characterized by intense skin itching (mainly at night) with irritating blisters or lumps on the skin mainly affecting the regions between the fingers, underarms, breasts, penis, buttocks, scalp, palms and soles.

IVERSCAB 12MG cannot be used prophylactically against all these infections and it does not work against adult worms. To avoid the spread of infection (e.g. scabies), frequently wash your clothing and bedding in hot water and keep all your non-washable items in a tightly sealed plastic bag for at least 3 days. Trim your nails frequently. People who come in contact with you (e.g. friends, family members and relatives) should also visit the doctor as soon as possible as a safety precaution. This medicine is generally safe and well tolerated. However, it may cause nausea, vomiting, stomach pain and muscle pain in few individuals. Contact your doctor if it bothers you. It is not recommended for use in pregnant or lactating women and in infants (weighing less than 15 kg). Consult your doctor before taking this medicine.

USES OF IVERSCAB 12MG

Onchocerciasis
Intestinal strongyloidiasis
Filarial worm infestations (e.g. lymphatic filariasis or microfilaraemia)
Hookworm infestations
Scabies
Pediculosis (head lice)
Helminthiasis (Ascariasis, Trichuriasis and Enterobiasis)

HOW IVERSCAB 12MG WORKS

Ivermectin is an antiparasitic agent. It acts against the parasite by selectively binding to the glutamate-gated chloride ion channels present in the nerve and muscle cells of the organisms. Binding of ivermectin to glutamate-gated chloride ion channels increase the influx of chloride ion which results in hyperpolarization, leading to paralysis and death of the parasite.

DIRECTIONS FOR USE

Take IVERSCAB 12MG as directed by your physician. It must be taken on an empty stomach either 2 hours before or after meals. Swallow the medicine as whole with a sip of water. In case of dispersible tablet, disperse the tablet in a teaspoonful of boiled and cooled water before administration. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the infection. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF IVERSCAB 12MG

SERIOUS
Allergic reactions (such as skin rash, itching, sudden fever, difficulty in breathing)
COMMON
Liver disease
Unusual weakness, dizziness
Nausea, vomiting, abdominal pain, diarrhea, constipation
Sweating or fever, cough
Headache
Muscle or joint or body pain
Confusion
Redness of eyes
Swelling of hands, feet, ankles and lymph nodes

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HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Stick to simple meals. Do not eat rich or spicy food.

Constipation:

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Abdominal pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Headache:

Rest and drink plenty of fluids. Do not drink too much alcohol. Ask your doctor to recommend a painkiller.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling dizzy. If the symptom still persists, contact your doctor for advice.

WARNING & PRECAUTIONS

PREGNANCY
IVERSCAB 12MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING
IVERSCAB 12MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES
Do not drive or operate any machines if your ability is affected by this medicine.

LIVER
IVERSCAB 12MG should be used with caution in patients having liver disease. Consult your doctor before taking.

ALLERGY
Do not take this medicine if you are allergic to ivermectin.

OTHERS

Before taking IVERSCAB 12MG, inform your doctor if you:

Have a weak immune system or if you are currently living or have lived in parts of Africa where there are cases of human parasitic infestation

INTERACTIONS

Talk to your doctor, if you are taking:

Diethylcarbamazine citrate (DEC) (a medicine used to treat a co-infection with Onchocerca volvulus)
Warfarin (used for blood thinning)