Isordil 5 tablet (Isosorbide Dinitrate 5mg)

INTRODUCTION

ISORDIL 5MG contains Isosorbide dinitrate which belongs to the group of medicines called Nitrate Vasodilators. It is used to prevent angina pectoris due to coronary artery disease and helps to control certain types of heart failure.

Angina pectoris is defined as a sudden, sharp, severe pain originating from the apex of heart and radiating to the left shoulder. The pain is severe and crushing, and it is characterized by feeling of pressure and suffocation, behind breastbone.

ISORDIL 5MG is not recommended for use if you have anaemia, had a heart attack, bleeding in the brain, head injury, very low blood pressure, low blood volume (hypovolaemia). Before taking ISORDIL 5MG, inform your doctor if you have any liver, kidney, heart, or thyroid problems, glaucoma, or extremely low body temperature. Avoid consumption of alcohol during treatment with ISORDIL 5MG as it may increase the risk of low blood pressure.

If you are pregnant or think you might be pregnant or planning to have a baby ask your doctor for advice before taking this medicine. ISORDIL 5MG should be used with caution in breastfeeding women. Consult your doctor before taking it. Along with the treatment, your doctor might advice you to make certain lifestyle changes such as quitting alcohol and smoking, improve your sleep at night, eating a healthy diet and manage weight.

The most common side effects of taking ISORDIL 5MG are headache, low blood pressure, dizziness when standing up, rapid heartbeat, drowsiness, tiredness, and swelling of the hands, ankles, or feet. Contact your doctor if any of the symptoms get worse.

USES OF ISORDIL 5MG

• Prevents angina pectoris
• Helps to control certain types of heart failure

HOW ISORDIL 5MG WORKS

ISORDIL 5MG works by relaxing the blood vessels of the heart and this reduces the strain on the heart making it easier to pump blood, thereby it provides relief from anginal symptoms.

DIRECTIONS FOR USE

Take ISORDIL 5MG as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you based upon your age and disease condition. Do not stop taking ISORDIL 5MG unless your doctor advises you to stop.

SIDE EFFECTS OF ISORDIL 5MG

HOW TO MANAGE SIDE EFFECTS

Headache:

Take rest and drink plenty of water. Try to be relaxed and stress free. Apply pain relieving balm on the forehead if necessary. Consult your doctor if the symptom does not improve.

Dizziness:

Try to rest and relax and get enough sleep. Try to avoid driving or operating any tools or machines while you are feeling dizzy. Limit your consumption of alcohol, as it can aggravate your dizziness. Consult and inform your doctor if the symptom does not improve.

Nausea or vomiting:

Try to take ISORDIL 5MG with or just after a meal or a snack. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug – Drug interactions:

Before taking ISORDIL 5MG, inform your doctor if you are taking any of the following medicines:

• Betablockers (Ex. atenolol), calcium channel blockers (Ex. amlodipine), vasodilators (Ex. hydralazine), ACE inhibitors (Ex. enalapril) (used to treat high blood pressure)
• Monoamine oxidase inhibitors such as phenelzine, selegiline and tricyclic antidepressants such as amitriptyline, amoxapine (used to treat depression)
• Neuroleptics such as thioridazine, chlorpromazine (used to treat symptoms of schizophrenia)
• Riociguat (used to treat pulmonary hypertension)
• Phosphodiesterase inhibitors such as sildenafil, tadalafil, or vardenafil (used to treat male erectile dysfunction)
• Ergotamine (used to treat migraine)
• Sapropterin (used to lower phenylalanine levels in the blood)

Overdosage:

If you or anyone else accidentally takes too much of ISORDIL 5MG, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are extremely low blood pressure, nausea or dizziness.