Glycomet-GP 0.5 Tablet (Glimepiride 0.5mg / Metformin 500mg)

Medical Description

Glycomet-GP 0.5 tablet an anti-diabetic medicine. It helps to manage blood sugar levels and prevent related complications. It is a combination medicine containing glimepiride and metformin. Some of the common side effects observed are low blood sugar levels which are characterised by sweating, tremors, confusion, blurred vision, tiredness and slow heartbeats. You can prevent it if you have regular balanced meals and the tablet as per the doctor’s recommendation. You are also advised to keep a regular check on your blood sugar levels. You may also experience a headache, change in taste, nausea, diarrhoea and stomach pain. Before using this medicine, inform the doctor if you are pregnant, planning a pregnancy or are breastfeeding and about your detailed medical history.

Uses of Glycomet Gp 0.5mg Strip Of 10 Tablets

Glycomet-GP 0.5 tablet is used to treat type 2 diabetes mellitus; when diet, exercise and glimepiride or metformin alone are not able to control the blood sugar levels adequately.

Contraindications of Glycomet Gp 0.5mg Strip Of 10 Tablets

If you are allergic to metformin, glimepiride or any other ingredients of Glycomet-GP 0.5 tablet.
If you are pregnant or are breastfeeding.
If you have serious kidney failure or liver failure.
If you have any metabolic acidosis (too much acid in the body fluids) like lactic acidosis, diabetic ketoacidosis or diabetic pre-coma.
If you have dehydration, severe infections, shock and injections containing iodine.
If you have had heart or lung failure, the recent incidence of heart attack and shock.
If you are an alcoholic.

Side effects of Glycomet Gp 0.5mg Strip Of 10 Tablets

Vomiting
Nausea
Diarrhoea
Stomach pain
Loss of appetite
Metallic taste
Low blood sugar level which can cause a headache, sweating, nausea, mood disorders and restlessness.

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Other General Warnings

Talk to your doctor if
You experience extreme hunger, headache, nausea, vomiting, sleepiness, restlessness, aggression, reduced alertness, confusion, shakiness or dizziness. These could be signs of low blood sugar. If you have any of these, immediately have sugar or sweet juice Inform your doctor as you may need a change in your medicine’s dose.
You are experiencing pins-and-needles sensation, numbness and weakness.
You are going to have a diagnostic imaging test that involves an injection of iodine.
You have dehydration due to diarrhoea, vomiting or limited fluid intake.
You have suffered through trauma.
You have to undergo surgery in the near future.
You have serious kidney and liver problems.
You have thyroid disorders.
You are overweight (specific diet restriction may be suggested).

Mode of Action of Glycomet Gp 0.5mg Strip Of 10 Tablets

How Does It Work?
This combination is known to control blood sugar to a greater extent than metformin or glimepiride alone. Glimepiride lowers the blood sugar level increasing the release of insulin hormone from the pancreas.
Insulin moves sugar (glucose) from the blood into the cells.
Metformin decreases the absorption in the intestine and production of sugar by the liver.
Both of these components are known to increase the insulin sensitivity of the body (which allows the cells of the body to use blood glucose more effectively, reducing blood sugar).

Directions for Use of Glycomet Gp 0.5mg Strip Of 10 Tablets

It should be consumed as a whole without chewing or crushing with a sufficient amount of water with food.

Interactions of Glycomet Gp 0.5mg Strip Of 10 Tablets

Interactions with other medicines
You may have symptoms of low blood sugar if you are taking other medicines for diabetes like Insulin, Pioglitazone, medicines for high blood pressure (ACE inhibitors like Captopril), Steroids, Chloramphenicol, Fenfluramine, Fenyramidol, medicines to lower blood cholesterol (fibrates), medicines to treat mood (Fluoxetine), medicines to treat blood clotting like Coumarins, Cyclophosphamide, Miconazole, Probenecid, antibiotics like Clarithromycin, Doxycycline, Ofloxacin, etc.
You may have symptoms of high blood sugar if you are taking oral contraceptives, Acetazolamide, water pills, Phenytoin, Rifampicin, medicines for constipation, Rifampicin and medicines for thyroid disorders.
Medicines like anti-allergic (ranitidine), clonidine, reserpine and medicines used to treat high blood pressure like atenolol can alter the way this medicine works and may block your body’s response to low blood sugar. This can lead to dangerously low levels of blood sugar.
Medicines like Diclofenac, Ibuprofen, Water pills, Enalapril may affect your kidney functions if taken along with this medicine.
Medicines used to treat thyroid can affect the way this medicine works.

Storage and disposal of Glycomet Gp 0.5mg Strip Of 10 Tablets

Store Glycomet-GP 0.5 tablets at room temperature in a dry place.
Protect it from moisture.
Keep it out of the reach of children and pets.

Dosage of Glycomet Gp 0.5mg Strip Of 10 Tablets

Overdose
An overdose of Glycomet-GP 0.5 tablet may lead to severe hypoglycaemia and lactic acidosis (Excessive lactic acid build-up) & (low blood sugar). This can result in a headache, nausea, vomiting, sleep disturbances, restlessness, impaired alertness and reactions, mood disorders, confusion, dizziness, etc.
If you experience these, immediately take glucose or juice or sugar-containing products (Sugar candy).
Contact your doctor immediately or visit the nearest hospital as you may require close monitoring for the next few hours.
Missed a Dose
A missed dose may lead to high blood sugar levels, which includes symptoms like feeling thirsty, excessive urination, loss of appetite, drowsiness, a fruity smell from breath, etc.
If you have missed any dose of Glycomet-GP 0.5 tablet, take it as soon as you remember.
If it’s time for your next dose, then skip the missed dose and continue with your regular dosing schedule.
Do not take a double dose of this medicine to compensate for the missed one.