Fragmin 5000IU Injection (Dalteparin 5000IU)

Description

FRAGMIN 5000IU INJECTION is an anticoagulant used to prevent the formation and growth of blood clots in patients with certain specific medical conditions. It is also used to prevent blood clots that may potentially form during certain medical procedures. It is used in combination with aspirin to prevent serious complications associated with angina and heart attacks.

Substitutes

List of substitutes for FRAGMIN 5000IU INJECTION
Daltepin 5000 IU Injection
Intas Pharmaceuticals Ltd.
Side effects
Major & minor side effects for FRAGMIN 5000IU INJECTION
Injection site redness, bruising, or sores
Unusual bleeding or bruising
Dark red spots in the mouth
Bloody or coffee colored vomit
Black or tarry stools
Excessive menstrual bleeding
Dizziness and lightheadedness
Swelling of eyelids, face, lips, tongue
Difficulty in swallowing
Difficulty in breathing
Back pain
Muscle weakness
Fever
Burning or tingling sensation of skin

Uses of FRAGMIN 5000IU INJECTION

What is it prescribed for?
Prophylaxis of ischemic complications in unstable angina
This medicine is used to prevent the blockage of coronary arteries (major blood vessels carrying blood and oxygen to the heart) and associated complications. A blockage of the coronary artery may result in a heart attack, anginal pain, and heart rhythm abnormalities. This medicine is administered along with aspirin to prevent these complications.
Prophylaxis for Deep Vein Thrombosis
This medicine is used for the prevention of blood clot formation in a deep vein, most commonly in the legs.
Deep Vein Thrombosis Prophylaxis after surgery
This medicine is used for the prevention of blood clot formation during and after major surgical procedures such as hip replacement surgery, major abdominal surgeries, etc.
Venous thromboembolic events
This medicine is used to treat and prevent the formation of blood clots in veins that could potentially break loose and migrate to larger veins in the legs or lungs, causing further complications.
Prophylaxis of ischemic complications in myocardial infarction
This medicine is used to prevent the blockage of coronary arteries (major blood vessels carrying blood and oxygen to the heart) and associated complications. A blockage of the coronary artery may result in a heart attack, anginal pain, and heart rhythm abnormalities. This medicine is administered along with aspirin to prevent these complications.

Related Products

List of related products
Fragmin 10000 IU Injection
Fragmin 10000 IU Prefilled Syringe
Fragmin 2500 IU Prefilled Syringe
Fragmin 5000 IU Prefilled Syringe
Fragmin 7500 IU Prefilled Syringe

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to dalteparin or any other inactive ingredient present along with it. Use of this medicine is also not recommended in patients having a known allergy to heparin or pork products.
Active major bleeding
This medicine is not recommended for use in patients with a known heavy active bleeding due to the increased risk of worsening of the patient’s condition.
Thrombocytopenia
This medicine is not recommended for use in patients with an abnormally low platelet count due to the increased risk of excessive bleeding.
Regional anesthesia
This medicine is not recommended for use in patients with unstable angina, non-Q-wave myocardial infarction, or cancer who are undergoing regional anesthesia due to the increased risk of excessive bleeding.
Epidural/spinal anesthesia
This medicine is not recommended for use for the prevention of venous thromboembolic events in patients receiving epidural/spinal anesthesia.

Warnings

Warnings for special population
Pregnancy
This medicine is recommended for use in pregnant women only when absolutely necessary and the potential benefits outweigh the risks involved.
Breast-feeding
This medicine is recommended for use in breastfeeding women only when absolutely necessary and the potential benefits outweigh the risks involved.
General warnings
Hemorrhage and risk factors
Use of this medicine should be initiated only after internal bleeding or hemorrhage and associated risk factors are ruled out. All the underlying causes of bleeding such as peptic ulcer disease, hemophilia, impaired hemostasis, etc. should also be ruled out before the administration of this medicine.
Thrombocytopenia
Use of this medicine may cause low levels of platelets (thrombocytopenia). It is advised to monitor the blood platelet levels at regular intervals while this medicine is administered. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Benzyl alcohol as preservative
Dosage forms containing benzyl alcohol as a preservative should not be administered to neonates, infants, pregnant or breastfeeding women. Benzyl alcohol may cause a fatal adverse event known as Gasping syndrome in neonates and infants.
Liver/kidney disease
This medicine should be used with caution in patients having an impairment of normal liver/kidney function. Appropriate dose adjustments and frequent clinical monitoring are recommended for such patients. Replacement with a suitable alternative may be necessary based on the clinical condition.
Other medicines
This medicine may interact with many other medicines and may cause severe side effects. Hence, you are advised to report the use of all medicines including herbs and supplements to the doctor before beginning treatment with this medicine.
Epidural/spinal/regional anesthesia
This medicine should not be used in patients receiving regional, epidural, or spinal anesthesia due to the increased risk of excessive bleeding and formation of hematoma.
Route of administration
This medicine should be administered subcutaneously. The intramuscular route of administration should be avoided.
Interchangeability with other heparins
This medicine should not be used interchangeably with other low molecular weight heparins.

Dosage

Missed Dose
This medicine is usually administered in a clinical or hospital setup. However, if you are administering it at home and miss a scheduled dose, then call your doctor immediately for further instructions.
Overdose
Seek emergency medical attention in case of an overdose or suspected overdose. Symptoms may include nosebleed, unusual bruising and bleeding, and the presence of blood in stool or urine.

General Instructions

Administer FRAGMIN 5000IU INJECTION exactly as instructed by the doctor. It should not be injected into the muscles. It is advised to administer this medicine under the supervision of a doctor in a clinical setup with regular monitoring of blood clotting time and other related parameters. Your doctor may ask you to undergo certain tests to determine the safety of use of this medicine.