Encorate Chrono 300 Tablet (Sodium Valproate/ Valproic Acid)

Encorate Chrono 300 Tablet

Encorate Chrono 300 Tablet is an anticonvulsant medication that consists of Sodium Valproate and Valproic Acid. It is used for the treatment of epilepsy, a neurological disorder in which the brain activity becomes abnormal, leading to uncontrolled jerking movements and loss of consciousness. This medicine works by decreasing the abnormal and excessive activity of the nerve cells in your brain.

Encorate Chrono 300 Tablet may cause side effects like nausea, vomiting, diarrhoea, headache, change in appetite, tremor, confusion, etc. Inform your doctor if these side effects bother you for a long time or become worse. Avoid driving vehicles or operating machines after taking this medicine, as it may cause drowsiness.

Encorate Chrono 300 Tablet is advised to be taken with food to avoid stomach discomfort. The dose and duration of treatment will be decided by your doctor based on your condition. Take this medicine for the recommended duration for better results. Do not stop taking Encorate Chrono 300 Tablet suddenly, as it may cause increased seizure frequency. Your doctor may gradually taper the dose over a period.

Encorate Chrono 300 Tablet should be avoided if you are allergic to it. Inform your doctor about your complete medical history, including any heart, liver, or kidney problems. Also, inform your doctor about all your current medications to avoid undesired effects. If you are pregnant, planning a pregnancy, or are breastfeeding, consult your doctor before taking Encorate Chrono 300 Tablet.

Side effects

Major & minor side effects for Encorate Chrono 300 Tablet
Nausea or Vomiting
Diarrhea
Blurred vision
Dizziness
Weight gain
Body pain
Skin rash
Sneezing
Dry skin
Urinary incontinence
Drowsiness
Change in appetite
Tremor
Hair loss
Confusion

Uses of Encorate Chrono 300 Tablet

What is it prescribed for?
Epilepsy
Epilepsy is a neurological condition in which your brain activity becomes abnormal, causing uncontrolled jerking movements and loss of consciousness. Encorate Chrono 300 Tablet is used in the treatment of all types of epilepsy.

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When not to use?

Allergy
Avoid taking Encorate Chrono 300 Tablet if you are allergic to it. Seek medical attention if you notice any symptoms like skin rash, itching/swelling (especially in the face/throat/tongue), dizziness, breathing difficulty, etc.
Active liver disease
Encorate Chrono 300 Tablet is not recommended for use if you have active liver problems due to the increased risk of liver toxicity.
Urea cycle disorders
Urea cycle disorders are a group of genetic disorders that affect how protein is broken down in your body. It may lead to the accumulation of toxic waste products in the blood. Encorate Chrono 300 Tablet is not recommended for use if you have urea cycle disorders as it may increase the risk of other complications that may be life-threatening.
Mitochondrial disorders
Mitochondrial disorders are a group of genetic disorders that occur when mitochondria (a component of the cell that produces energy) fail to produce enough energy for your body to function properly. Encorate Chrono 300 Tablet is not recommended for use if you have mitochondrial disorders (e.g., Alpers-Huttenlocher Syndrome) as it may further worsen your condition.
Porphyria
Porphyria is a condition that occurs due to the build-up of a chemical called porphyrin in your body. It affects the production of heme which transports oxygen in your blood. It can cause nerve or skin problems. Encorate Chrono 300 Tablet is not recommended for use if you have porphyria as it may worsen your condition.

Warnings

Warnings for special population
Pregnancy
Encorate Chrono 300 Tablet is unsafe for use during pregnancy as it can harm your developing foetus. Therefore, consult your doctor if you are pregnant.
Breast-feeding
Encorate Chrono 300 Tablet is not safe for use while breastfeeding as it passes into the breastmilk and may harm your baby. Therefore, consult your doctor if you are breastfeeding.
General warnings
Pancreatitis
Pancreatitis is a swelling of the pancreas (a gland that produces chemical substances which help in digestion and regulation of blood sugar). Encorate Chrono 300 Tablet should be used with caution as it may cause severe pancreatitis in some cases. Inform your doctor if you experience any signs and symptoms such as nausea, vomiting, or acute abdominal pain that persist or worsen.
Impaired kidney function
Encorate Chrono 300 Tablet should be used with caution if you have kidney problems, as it may lead to the accumulation of this medicine in the body and increase the risk of undesired effects. Your doctor may adjust the dose of this medicine based on your clinical condition.
Lupus erythematosus
Lupus erythematosus is an autoimmune disorder (a condition where the immune system attacks its own tissues) that causes swelling and tissue damage in the affected organs. Encorate Chrono 300 Tablet should be used with caution if you have lupus erythematosus, as it may worsen your condition.
Driving and operating machines
Encorate Chrono 300 Tablet may cause drowsiness or dizziness. Hence, avoid driving vehicles or operating machines if you feel drowsy or dizzy after taking this medicine.

Dosage

Missed Dose
Take the missed dose of Encorate Chrono 300 Tablet as soon as you remember. If it is time for the next scheduled dose, skip the missed dose. Do not use extra medicine to make up for the missed dose.
Overdose
Never take more than the recommended dose. Contact your doctor in case of an overdose of Encorate Chrono 300 Tablet.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended while taking Encorate Chrono 300 Tablet as it may increase the risk of side effects such as dizziness, drowsiness, and difficulty in concentration.
Interaction with Medicine
Lamotrigine
Metoclopramide
Warfarin
Disease interactions
Depression
Encorate Chrono 300 Tablet should be used with caution due to the increased risk of depression and suicidal thoughts. If you notice any behavioural changes or develop thoughts of self-harm, consult your doctor immediately.
Food interactions
Information not available.
Lab interactions
Thyroid function tests
Thyroid function tests are blood tests done to measure the thyroid hormones level in your blood. Encorate Chrono 300 Tablet may alter the results of thyroid function tests. Hence, inform your doctor and laboratory technician about the use of this medicine before undergoing the test.
Urine ketone test
A urine ketone test is done to check the level of ketones (chemicals made in your liver) in your urine. Encorate Chrono 300 Tablet may give a false-positive result for the urine ketone test. Hence, inform your doctor and laboratory technician about the use of this medicine before undergoing the test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Encorate Chrono 300 Tablet preferably with food to avoid stomach discomfort. Do not take in larger or smaller amounts than advised. Take this medicine for the recommended duration.

Consult your doctor if you experience any undesirable effects that persist or worsen.

Avoid consumption of alcohol while taking this medicine as it may increase the risk of side effects.

Encorate Chrono 300 Tablet may cause weight gain. Hence, monitor your weight while you are taking this medicine and adopt appropriate measures to minimise it.