Channel-SR 90 Tablet (Diltiazem 90mg)

INTRODUCTION

CHANNEL SR 90MG contains Diltiazem which belongs to a group of medicines called calcium-channel blockers. It is used to treat high blood pressure and angina. It works by making your blood vessels wider. This helps to lower your blood pressure and also makes it easier for your heart to pump blood around the body. It also helps to prevent the chest pain caused by angina. Angina pectoris is a type of chest pain caused due to an inadequate supply of oxygen to the heart muscle.

The most common side effect of taking this medicine are nausea, vomiting, stomach pain, constipation, feeling dizzy or headache. This medicine is strictly not recommended for use in children. Consult your doctor before taking. It is advisable to limit the amount of grapefruit juice you drink while taking this medicine, as it can increase the blood levels of diltiazem and increases toxicity. Do not take this medicine if you are a pregnant or breastfeeding woman. Consult your doctor for advice before taking any medicine.

USES OF CHANNEL SR 90MG

Treat (long-term) and prevent angina pectoris
Treat mild to moderate high blood pressure

HOW CHANNEL SR 90MG WORKS

Diltiazem is a slow calcium channel blocker that binds to the extracellular site of the alpha-1C subunit of the channel. It inhibits the entry of extracellular calcium across the myocardial and vascular smooth muscle cell membranes. The reduced intracellular calcium concentrations will increase smooth muscle relaxation, resulting in arterial vasodilation and therefore, decrease blood pressure. It also increases the supply of blood and oxygen to the heart.

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DIRECTIONS FOR USE

Always take CHANNEL SR 90MG as directed by your physician. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the dose and duration depending upon your condition. Limit the amount of grapefruit juice you drink while taking this medicine, as it can increase the blood levels of diltiazem and may increase your chance of getting side effects.

SIDE EFFECTS OF CHANNEL SR 90MG

SERIOUS
Slow or uneven heartbeat
Very fast, uneven or forceful heartbeat (palpitations)
COMMON
Nausea or vomiting
Indigestion or diarrhea
Stomach pain
Constipation
Feeling tired or dizzy
Headache
Flushing (feeling of warmth)
Skin redness
Difficulty in sleeping
RARE
Dry mouth
Itchy, lumpy rash (urticaria)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after, a meal and stick to simple meals and do not eat rich or spicy food.

Constipation:

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

Skin redness:

Avoid hot showers or baths because hot water can irritate the skin. Moisturizers can be used regularly to soothe and hydrate the affected area.

INTERACTIONS

Talk to your doctor, if you are taking,

Dantrolene or cilostazol (used for severe muscle spasms)
Ivabradine (used to treat certain heart diseases)
Other medicines used to treat high blood pressure such as doxazosin, tamsulosin, atenolol, propranolol or acebutolol
Medicines used to treat arrhythmia (uneven heartbeat) such as amiodarone and digoxin
Other medicines used for angina (such as glyceryl trinitrate or isosorbide trinitrate)
Medicines used to treat high levels of cholesterol (simvastatin, fluvastatin and atorvastatin)
Ciclosporin (used to stop graft rejection)
Medicine used to treat epilepsy (e.g. phenytoin and carbamazepine)
Medicines used to stop blood clotting (aspirin or clopidogrel)
Theophylline (used to treat breathing problems)
Lithium (used to treat depression)
Medicines used for anxiety (triazolam or midazolam)
Methylprednisolone (used to treat inflammation)
Rifampicin used to treat tuberculosis