Canrolfin Cream (Amorolfine 0.25%) 30gm

INTRODUCTION

CANROLFIN contains Amorolfine which belongs to the group of medicines called antifungals. It is used in the treatment of fungal skin infections caused by dermatophytes such as tinea pedis (athlete foot), tinea cruris (also known as jock itch, that causes a red and itchy rash in the groin and inner thighs), tinea corporis (also known as ringworm, a fungal infection of arms and legs) and tinea manuum (fungal infection on both hands).

It can also be used to treat cutaneous candidiasis and pityriasis versicolor (a yeast infection of the skin that causes small, discoloured patches of skin). Amorolfine effectively kills the infection-causing organisms by inhibiting the biosynthesis of ergosterol. It alters cell membrane permeability, disrupts cellular metabolic processes and causes cell death.

Apply CANROLFIN on the affected areas once daily preferably in the evening. Continue to apply this medicine, as long as your doctor tells you to do so, to obtain better results. Always avoid contact of this medicine with your nose, eyes, ears or on mucous membranes (such as mouth and nostrils). If accidentally contact happens, wash it out with water immediately and contact your doctor immediately. Stop applying this medicine and seek immediate medical attention if you experience any signs of allergic reactions such as skin rash. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to a doctor.

USES OF CANROLFIN

Treats tinea cruris, tinea corporis and pityriasis versicolor

HOW CANROLFIN WORKS

Amorolfine kills the fungi by inhibiting the biosynthesis of ergosterol, an essential component of fungal cell membranes. This leads to alternation in fungal cell membrane permeability, disruption of key fungal metabolic processes and cell death.

DIRECTIONS FOR USE

Apply CANROLFIN as directed by your physician. It should be applied to the affected areas of the skin once daily (in the evening). It is for external use only. Continue to apply this medicine, as long as your doctor tells you to do so, to obtain better results. In general, this medicine should be continued for at least 2–3 weeks. In foot mycoses, therapy up to 6 weeks may be necessary. Always avoid contact of this medicine with your nose, eyes, ears or on mucous membranes (such as mouth and nostrils). If accidentally contact happens, wash it out with water immediately and contact your doctor immediately.

SIDE EFFECTS OF CANROLFIN

SERIOUS
Systemic allergic reaction (such as skin rash, swelling of face, lips, tongue or throat and difficulty in breathing)
RARE
Skin irritation or erythema
Pruritus
Burning sensation

HOW TO MANAGE SIDE EFFECTS

Avoid hot showers because hot water can irritate the scalp. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, speak to a doctor.

WARNING & PRECAUTIONS

PREGNANCY
CANROLFIN should be used during pregnancy only if it is clearly necessary. Consult your doctor for advice before taking this medicine.

BREASTFEEDING
CANROLFIN should be used during breastfeeding only if it is clearly necessary. Consult your doctor for advice before taking this medicine.

DRIVING AND USING MACHINES
This medicine does not affect your ability to drive or operate machines.

ALLERGY
Do not take this medicine if you are allergic (hypersensitive) to amorolfine or any other ingredients in this medicine.

OTHERS
This medicine is not recommended for use in children as well as in elderly patients due to lack of safety data. Consult your doctor before using.

INTERACTIONS

Tell your doctor if you are using or have recently used any other topical medications.