Brinzox Eye Drops (Brinzolamide 1%)

About Brinzox Eye Drops 5 ml

Brinzox Eye Drops 5 ml belongs to a class of anti-glaucoma agents called carbonic anhydrase inhibitors primarily used to treat increased pressure in the eye in conditions. Glaucoma is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow).

Brinzox Eye Drops 5 ml contains Brinzolamide that works by inhibiting the action of carbonic anhydrase enzyme and decreasing bicarbonate production essential for the production of fluid of the eye (aqueous humour).  Thus it reduces the secretion of eyes fluid called ‘aqueous humour’ that maintains pressure in the eyeball and in turn lowers the raised pressure in the eye by reducing aqueous humour entry into the eyeball. Thus, Brinzox Eye Drops 5 ml prevents eyes from getting blind in the conditions of open-angle type glaucoma and ocular hypertension.

Brinzox Eye Drops 5 ml is only for use in the eyes. Do not swallow or inject Brinzox Eye Drops 5 ml. Apply one drop of Brinzox Eye Drops 5 ml in the morning and night in the affected eye. Your doctor will advise you how many drops to instil based on your medical condition. In some cases, you may experience eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. Most of these side effects of Brinzox Eye Drops 5 ml do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Brinzox Eye Drops 5 ml or any other medicines, please tell your doctor. Brinzox Eye Drops 5 ml is not recommended for children below 18 years of age. You are not advised to use Brinzox Eye Drops 5 ml if you are pregnant, breastfeeding or have severe kidney problems or hyperchloraemic acidosis (excessive acidity in the blood). You are advised to remove soft contact lenses before using Brinzox Eye Drops 5 ml as it may cause discolouration of the soft contact lens. If you get any new eye problem, an eye infection or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain a 5 minutes time gap between using Brinzox Eye Drops 5 ml and other eye drops. If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma or pigmentary glaucoma kidney or liver problems, before taking Brinzox Eye Drops 5 ml.

Uses of Brinzox Eye Drops 5 ml

Glaucoma (open-angle type), Ocular hypertension (high eye pressure)

Medicinal Benefits

Brinzox Eye Drops 5 ml contains Brinzolamide used to treat increased pressure in the eye in conditions such as glaucoma (damage of optic nerve) and ocular hypertension (high fluid pressure inside the eye). Brinzox Eye Drops 5 ml inhibits the action of carbonic anhydrase enzyme and decreases bicarbonate production that is essential for the production of aqueous humour.  Thereby, it reduces the secretion of aqueous humour (a liquid that maintains normal pressure in the eyeball) and lowers the pressure in the eye by reducing aqueous humour entry into the eyeball.

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Directions for Use

Use Brinzox Eye Drops 5 ml as prescribed by a doctor. Apply one drop of Brinzox Eye Drops 5 ml in the morning and the night in the affected eye. Your doctor will advise you how many drops to instil based on your medical condition. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Brinzox Eye Drops 5 ml and cause eye infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Brinzox Eye Drops 5 ml

Like all medicines, Brinzox Eye Drops 5 ml can cause some common side effects such as eye discharge, redness, itching, irritation or pain in the eyes, blurred vision, abnormal eye sensation and dry eyes. Most of the side effects of Brinzox Eye Drops 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. If you get any new eye problem, an eye infection or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately.

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Brinzox Eye Drops 5 ml or any other medicines, please tell your doctor. Brinzox Eye Drops 5 ml is not recommended for children below 18 years of age. You are not advised to use Brinzox Eye Drops 5 ml if you are pregnant, breastfeeding, or have severe kidney problems or hyperchloraemic acidosis (excessive acidity in the blood). You are advised to remove soft contact lenses before using Brinzox Eye Drops 5 ml as it may cause discolouration of the soft contact lens. If you get any new eye problem, an eye infection or notice any allergic reactions such as itching or redness of the eye and skin rash, please consult your doctor immediately. You are advised to maintain a 5 minutes time gap between using Brinzox Eye Drops 5 ml and other eye drops. Please do not touch the container tip to the eye, eyelids or surrounding areas as it may contaminate Brinzox Eye Drops 5 ml and cause eye infections. If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma or pigmentary glaucoma kidney or liver problems, before taking Brinzox Eye Drops 5 ml.

Drug Interactions

Drug-Drug Interaction: Brinzox Eye Drops 5 ml may have interaction with medicines used to treat glaucoma (dorzolamide, acetazolamide, methazolamide, dichlorphenamide), antidiarrheal agents (bismuth subsalicylate), pain relievers (choline salicylate, aspirin, diflunisal, magnesium salicylate, salsalate, sodium salicylate, sodium thiosalicylate), anticonvulsants (topiramate, zonisamide).

Drug- Food Interaction: No interactions found.

Drug-Disease Interaction: If you have dry eyes, cornea problems, narrow-angle glaucoma, pseudoexfoliative glaucoma or pigmentary glaucoma kidney or liver problems, before taking Brinzox Eye Drops 5 ml.