Apivas 2.5mg Tablet (Apixaban 2.5mg)

INTRODUCTION

APIVAS 2.5 contains apixaban which belongs to the group of medicines called anticoagulants. A blood clot which blocks an artery (blood vessel) is called an embolism and if the embolism occurs in the arteries of the brain it can cause a stroke. Anticoagulants slow down the time it takes for blood to clot and reduce the risk of embolism.

This medicine is used to reduce the risk of blood clots formation in heart of the patients with atrial fibrillation (an abnormal heartbeat) and other risk factors for stroke. These blood clots might break and travel to the brain, leading to a stroke or to other organs and prevent their normal blood flow (systemic embolism).

APIVAS 2.5 can also be used to treat other blood clotting conditions like deep vein thrombosis (blood clots in veins of legs) and pulmonary embolism (blood clot in blood vessels of lungs), and also prevents its recurrence in patients with or without hip or knee replacement operations. This medicine can be taken with or without food.

The most common side effects of taking this medicine are bleeding in eyes, nose, gums, stomach, rectum or vagina. Do not take this medicine, if you have any bleeding disorders. Discuss the risks and benefits with your doctor. Before taking this medicine inform your doctor if you are pregnant, breastfeeding or having any serious kidney or liver disease. This medicine is not recommended for use in children and adolescents under 18 years of age. Consult your doctor before taking.

USES OF APIVAS 2.5

• Prevents formation of blood clot in the heart of the patients with an irregular heartbeat (atrial fibrillation)
• Treats and prevents deep vein thrombosis (blood clots in veins of legs)
• Treats and prevents pulmonary embolism (blood clot in blood vessels of lungs) in patients with or without hip or knee replacement operations

HOW APIVAS 2.5 WORKS

APIVAS 2.5 selectively inhibits both the free- and clot-bound forms of coagulation factor Xa and the activity of prothrombinase which prevents the conversion of prothrombin into thrombin and thus preventing formation of blood clot.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. It can be taken with or without food. Your doctor will decide the correct dose for you depending upon your condition. Swallow the medicine as whole with a glass of water.

SIDE EFFECTS OF APIVAS 2.5

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea):

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor, if you are taking,

• Medicines used to treat fungal infections (e.g., ketoconazole)
• Medicines used to treat HIV infections (e.g., ritonavir)
• Medicines used to treat tuberculosis or other infections (e.g., rifampicin)
• Other medicines used to reduce blood clotting (e.g., enoxaparin, warfarin, rivaroxaban, dabigatran or heparin)
• Medicines used to reduce pain or inflammation (e.g., acetylsalicylic acid or naproxen).
• Medicines used for high blood pressure or heart problems (e.g., diltiazem)
• Medicines used to treat depression (e.g.  fluoxetine, sertraline, imipramine, St John’s Wort)
• Medicines used to prevent epilepsy or seizures (e.g., phenytoin, etc.)