Amtas-E Tablet (Amlodipine 5mg / Enalapril 5mg)

Amtas-E (5/5 mg) Tablet is a combination medicine used for the treatment of high blood pressure. This medicine should be used with caution in patients with heart diseases. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect.

Major & minor side effects for Amtas-E (5/5 mg) Tablet

Blurred vision

Confusion

Dizziness when getting up suddenly from a sitting position

Cough

Chest pain

Fever or chills

Vomiting

Skin rash

Lack of strength

Increase in the potassium levels

Swelling of ankles or feet

Difficulty in breathing

Dizziness

Increased heartbeat

Redness of face, neck, arms and chest

Muscle pain

Heartburn

Acid or sour stomach

Anxiety

What is it prescribed for?

Hypertension

This medicine is used in the treatment of high blood pressure which may be caused by genetic or environmental factors.

Allergy

This medicine is not recommended for use in patients with a known allergy to amlodipine, other calcium-channel blockers, enalapril, or any other ACE inhibitors.

Aliskiren

Coadministration of aliskiren and this combination medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

General warnings

Hypotension

Symptomatic hypotension may occur in patients with volume depletion or patients who are treated with high-dose diuretics. It is advised to correct this condition before initiating treatment with this combination medicine.

Hyperkalemia

This medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.

Pediatric population

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Cough

This medicine may cause a persistent nonproductive cough in some patients. It is resolved when the medicine is discontinued.

Impaired liver function

This medicine may rarely cause liver injuries such as jaundice or hepatitis. Close monitoring of liver function is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Coronary artery diseases

This medicine should be used with caution in patients with coronary artery diseases since it may worsen the patient’s condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Carbamazepine

Itraconazole

Losartan

Corticosteroids

Rifampicin

Aliskiren

Insulin

Diclofenac

Disease interactions

Angioedema

This medicine is not recommended for use in patients with a history of angioedema or a family history of angioedema due to the increased risk of recurrent symptoms. Report any incidence of swelling of the face, lips, and eyes to the doctor on priority. Replacement with a suitable alternative may be required based on the clinical condition.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient’s condition.

Food interactions

Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

Take this medicine exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.