Urimax D Tablet (Tamsulosin 0.4mg / Dutasteride 0.5mg)

INTRODUCTION

URIMAX is a combination of Dutasteride and Tamsulosin which belongs to the group of medicines called 5-Alpha reductase inhibitors and Alpha-blockers respectively. URIMAX is used to treat Benign Prostatic Hyperplasia (BPH) in adult men. Benign Prostatic Hyperplasia (also known as enlarged prostate) is a non-cancerous growth of prostate gland, which is predominantly caused by excessive production of a stress hormone called dihydrotestosterone (DHT) in men. Symptoms of BPH includes urinary problems such as difficulty in passing urine, urinary incontinence (unintentional passing of urine), frequent urination at night and sexual dysfunction or painful ejaculation.

Dutasteride acts by reducing the production of dihydrotestosterone, which helps the prostate to shrink and Tamsulosin acts by relaxing the muscles surrounding your prostate gland, making it easier for the urine to pass through, thus rapidly improving the symptoms of BPH. During this therapy, your doctor will regularly monitor your serum prostate-specific Antigen (PSA) levels to detect the incidence of prostate cancer.

Before taking URIMAX inform your doctor if you have any liver or kidney problems. Both pregnant women and children should avoid handling the leaking medicine, because this medicine has a high potential to get absorbed through your skin and can affect the normal development of a male baby (especially during the first 16 weeks of pregnancy).

Usage of condom during sexual intercourse is recommended among fertile men to avoid conception. URIMAX is not recommended for use in child or adolescent under 18 years of age. The most common side effects of taking URIMAX are dizziness, enlargement of breast in men and decreased sex drive. Contact your doctor if any of these symptoms bothers you.

USES OF URIMAX

• To treat Benign Prostatic Hyperplasia (BPH) in adult men

HOW URIMAX WORKS

URIMAX reduces the symptoms of Benign Prostatic Hyperplasia, where dutasteride works by reducing the production of a stress hormone called dihydrotestosterone and Tamsulosin works by relaxing the muscles surrounding the prostate gland, thus helps in shrinkage of prostate, making it easier for the urine to pass through and relieve the symptoms.

DIRECTIONS FOR USE

Always take URIMAX as directed by your physician. Take this medicine with or without food, swallow the medicine as a whole and do not crush or chew the medicine. Do not stop taking URIMAX without informing your doctor.

SIDE EFFECTS OF URIMAX

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Avoid consumption of alcohol as it can aggravate your dizziness. If the symptom persists for a longer time, contact your doctor for advice.

Nausea and Vomiting:

Take this medicine with, or just after, a meal or snack and stick to simple meals and do not eat oil rich or spicy food. Consult your doctor if the symptom does not improve.

Headache:

Apply hot or cold-water bag on your head. Try taking rest in a quiet and dark room. Drink tea or coffee. Consult your doctor if the symptom does not improve.

Constipation:

Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interaction:

Before taking URIMAX inform to your doctor, if you are taking any of these medicines:

• Other alpha blockers (used to treat enlarged prostate or high blood pressure) such as prazosin, doxazosin, terazosin
• Medicines used to treat erectile dysfunction (Ex. vardenafil, sildenafil and tadalafil)
• Medicines used to treat fungal infections (Ex. itraconazole, ketoconazole or terbinafine)
• Diltiazem or verapamil (used to treat angina or high blood pressure)
• Ritonavir or indinavir (used to treat HIV infections)
• Paroxetine or nefazodone (a medicine used to treat depression)
• Cimetidine (a medicine used to treat stomach ulcers)
• Warfarin (used to treat blood clotting)
• Erythromycin (used to treat bacterial infections)
• Diclofenac (a medicine used to treat pain or inflammation)

Overdosage:

If you or anyone else accidentally take too much of URIMAX, consult your doctor immediately. Overdosage may cause acute hypotension, nausea, and vomiting.