Pionorm-GM Tablet (Glibenclamide 5mg / Metformin 500mg / Pioglitazone 15mg)

Overview

Pionorm GM Tablet is used for Type 2 diabetes mellitus, Maturity onset diabetes, Treatment of type 2 diabetes mellitus, Polycystic ovary syndrome, Lower blood glucose in adults with type 2 diabetes mellitus and other conditions. Pionorm GM Tablet may also be used for purposes not listed in this medication guide.

Pionorm GM Tablet contains Glibenclamide, Metformin and Pioglitazone as active ingredients.
Pionorm GM Tablet works by stimulating the release of insulin from the pancreas; decreasing the amount of glucose and controls the amount of glucose in the blood; helping the body make better use of insulin by decreasing the glucose output;
Detailed information related to Pionorm GM Tablet’s uses, composition, dosage, side effects and reviews is listed below.
Uses
Pionorm GM Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
Type 2 diabetes mellitus
Maturity onset diabetes
Treatment of type 2 diabetes mellitus
Polycystic ovary syndrome
Lower blood glucose in adults with type 2 diabetes mellitus

Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Pionorm GM Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
Low blood sugar
Nausea
Epigastric fullness
Heartburn
Pruritus
Erythema
Urticaria
Morbilliform or maculopapular eruptions
Leukopenia
Agranulocytosis
Thrombocytopenia
Hemolytic anemia
Aplastic anemia
Pancytopenia
Blurred vision
Allergic reactions
Gastrointestinal disturbances
Low ph in body tissues and blood
Lack or loss of appetite for food
Vomiting
Diarrhoea
Weight loss
Flatulence
Altered sense of taste includes metallic taste
Rash
Malabsorption of vitamin b12
Skin reactions
Abdominal pain
Bone fracture
Weight gain
Inflammation of a nasal sinus
Bladder cancer
Visual disturbance
Impaired liver cell function
Infection of nose
Decreased sensitivity to stimulation
Inability to sleep
Rare elevated liver enzyme
Inflammation of the pharynx
Oedema
Headache
Upper respiratory tract infection
Anaemia
Joint pain
Presence of blood in urine
Impotence
Pionorm GM Tablet may also cause side-effects not listed here.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.

Related Product

Precautions

Before using Pionorm GM Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
Be careful while using it with insulin or renal hypoglycaemics
Blurred vision
Check the blood sugar regularly
Consult a doctor if you have any mental confusion, persistent abdominal pain, dark urine, yellowing of skin/eyes or easy bruising
Consult a doctor if you have oedema, congestive heart failure, hepatic dysfunction, jaundice, anaemia
Diabetic ketoacidosis
Elderly patients
Monitor therapeutic response to glyburide by urine and blood glucose tests
Pregnancy
Proper diet and physical activity are important in disease management

Interactions with Pionorm GM Tablet

If you use other drugs or over the counter products at the same time, the effects of Pionorm GM Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Pionorm GM Tablet may interact with the following drugs and products:
Anti-diabetic drugs
Beta adrenergic blocking agents
Beta blockers
Bosentan
Calcium channel blocking drugs
Chloramphenicol
Ciprofloxacin
Corticosteroids
Coumarins
Diuretics

When not to use Pionorm GM Tablet

Hypersensitivity to Pionorm GM Tablet is a contraindication. In addition, Pionorm GM Tablet should not be used if you have the following conditions:
Acute myocardial infarction
Cardiovascular collapse
Concomitant administration of bosentan
Diabetic ketoacidosis
Hypersensitivity
Hypersensitivity to this drug
Renal disease
Septicemia
Type 1 diabetes mellitus
Type I diabetes mellitus

Composition and Active Ingredients

Pionorm GM Tablet is composed of the following active ingredients (salts)
Glibenclamide – 5 MG
Metformin – 500 MG
Pioglitazone – 15 MG