Pasitrex Ointment (Calcipotriol 0.005%)

INTRODUCTION

PASITREX contains Calcipotriol which belongs to a group of medicines called anti-psoriatics. It is used to treat topical treatment of plaque psoriasis. It is a type of vitamin D which controls how the cells in your skin grow. Psoriasis is a condition where skin develops raised red patches and silver coloured scaly patches. These scaly patches are dead cells that would normally fall off your skin without you noticing. It works by reducing the amount of cells your skin makes which reduces the skin symptoms.

Calcipotriol is a synthetic analog of vitamin D3 occurs in the human body. Calcipotriol is the metabolite of cholecalciferol (inactive vitamin D3). It binds to vitamin D receptors on epidermal cells and tissue cells. Activation of this ligand-receptor complex results in inhibition of proliferation of keratinocytes and induction of cell differentiation in psoriatic skin.

Always use this PASITREX, exactly as prescribed by your doctor. Before using this medicine, tell your doctor, if you have or had any allergic, skin infections, pregnant women or breastfeeding mothers. It is not recommended for children below 6 years of age. The common side effects are skin irritation, burning and itching. Avoid contact with the face, eyes or mucous membranes as it may irritate the skin, if accidentally gets wash immediately with water.

USES OF PASITREX

Treats plaque psoriasis

HOW PASITREX WORKS

PASITREX binds to vitamin D receptors on epidermal cells and tissue cells. Activation of this ligand-receptor complex results in inhibition of proliferation of keratinocytes and induction of cell differentiation in psoriatic skin.

DIRECTIONS FOR USE

Always use PASITREX as prescribed by your doctor. It is for external use only. It has to be applied to the lesions in hairy areas on the body or scalp twice daily and should not be applied on the face. Check the label for directions before use.

Open the cap
Always wash your hands before using this medicine
Apply on the skin thickly and gently rub to cover the psoriasis
Wash your hands after application

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SIDE EFFECTS OF PASITREX

SERIOUS
Breathing difficulty
Swelling of face around your eyes
Severe rash
COMMON
Skin irritation
Worsening of psoriasis
Dermatitis
Redness
Flaking skin
Burning or stinging feeling
Itchy rash, skin inflammation and pain (application site)
RARE
Allergic reaction
Hypercalcaemia
Temporary increased sensitivity to sunlight
Skin swelling or puffiness (oedema)
Hypercalciuria

WARNING & PRECAUTIONS

PREGNANCY
PASITREX should be used with caution in pregnant women. Consult your doctor before taking.

BREASTFEEDING
PASITREX should be used with caution in breastfeeding mothers. Consult your doctor before using.

KIDNEY
PASITREX is not recommended in patients with active kidney diseases. Before using discuss the risks and benefits with your doctor.

LIVER
PASITREX is not recommended in patients with active liver diseases. Before using discuss the risks and benefits with your doctor.

ALLERGY
Do not use if you are allergic (hypersensitive) to Calcipotriol.

OTHERS

Inform your doctor if you have or had,

Hypercalcemia
Ultraviolet (UV) light treatment
Guttate, erythrodermic

INTERACTIONS

Tell your doctor if you are using or have recently taken any other medicines, including medicines obtained without a prescription.