Pangraf 0.5 Capsule (Tacrolimus 0.5mg)

Description

Pangraf 0.5 MG Capsule is an immuno-suppressant medicine. It is used to prevent organ rejection ((when your body’s immune system treats the transplanted organ as a foreign object and attacks it) after a kidney, liver, or heart transplantation. It works by decreasing the activity of the immune system (defence system rejecting foreign substances) and helps in preventing the rejection of the transplanted organ by the body.

Pangraf 0.5 MG Capsule has some side effects like headache, nausea, vomiting, diarrhoea, constipation, dizziness, back or joint pain, loss of appetite, etc. These side effects may subside by themselves. However, consult your doctor if they bother you for a longer time or worsen. Avoid taking this medicine if you are allergic to it.

Pangraf 0.5 MG Capsule should be taken on an empty stomach, one hour before or two hours after a meal. Follow all the instructions given by your doctor. Avoid taking more than the recommended dose. Take it every day at the same time for the ease of remembering and for better results.

Pangraf 0.5 MG Capsule may not be suitable for everyone. Inform your doctor if you have liver, heart, or kidney problems, high blood pressure, or diabetes. Also, inform your doctor about your ongoing medications to avoid undesired effects. Consult your doctor if you are pregnant or are breastfeeding.

Substitutes

List of substitutes for Pangraf 0.5 MG Capsule
Emgraf 0.5 MG Capsule
Emcure Pharmaceuticals Ltd.
Taclicept 0.5 MG Capsule
Lupin Ltd.
Tacroforce 0.5 MG Capsule
Ipca Laboratories Pvt. Ltd.
Tacromus 0.5 MG Capsule
Zydus Cadila
Takfa 0.5 MG Capsule
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Pangraf 0.5 MG Capsule
Headache
Diarrhoea
Dizziness
Nausea or Vomiting
Swelling of feet or lower legs
Blurred vision
Sweating
Weight loss
Back pain
Joint pain
Scaly skin
Loss of appetite

Uses of Pangraf 0.5 MG Capsule

What is it prescribed for?
Organ Transplant – Rejection Prophylaxis
An organ transplant is a procedure to replace the damaged organ with a donor organ. In this process, the body’s immune system acts against the transplanted organ and may reject it, resulting in failure of the procedure. Pangraf 0.5 MG Capsule is used to prevent organ transplant rejection in kidney, liver, and heart transplantation.

Related Product

When not to use?

Allergy
Avoid taking Pangraf 0.5 MG Capsule if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Warnings

Warnings for special population
Pregnancy
Pangraf 0.5 MG Capsule is not recommended for use during pregnancy as it may cause harm to the developing foetus. Hence, consult your doctor if you are pregnant.
Breast-feeding
Pangraf 0.5 MG Capsule is not recommended for use while breastfeeding as it may pass into the breastmilk. Hence, consult your doctor if you are breastfeeding.
General warnings
Lymphoma
Pangraf 0.5 MG Capsule should be used with caution as long-term treatment with this medicine may increase the risk of lymphoma (cancer that begins in infection-fighting cells of the immune system).
Serious infections
Pangraf 0.5 MG Capsule should be used with caution as it can weaken your immune system and make you prone to serious infections. Inform your doctor if you experience sore throat, cough, fever, skin infection, etc.
Kidney impairment
Pangraf 0.5 MG Capsule should be used with caution if you have kidney problems as it may increase the risk of kidney toxicity. Your doctor may adjust the dose of this medicine based on your clinical condition.
Hypertension
Hypertension refers to high blood pressure. Pangraf 0.5 MG Capsule should be with caution if you have hypertension, as this medicine may lead to an elevation in blood pressure and further worsen your condition. Monitor your blood pressure regularly while you are taking this medicine.
Hyperkalaemia
Pangraf 0.5 MG Capsule should be used with caution as it may cause hyperkalaemia (an increase in the blood potassium levels). This may further lead to an irregular heartbeat. Your doctor may suggest tests to closely monitor your potassium level if necessary while you are taking this medicine.
Driving vehicles or operating machines
Pangraf 0.5 MG Capsule may cause blurred vision or dizziness. Hence, avoid driving vehicles or operating machines if you experience such symptoms.
Liver Impairment
Pangraf 0.5 MG Capsule is broken down in the liver. Hence, it should be used with caution if you have liver problems, as it may increase the accumulation of this medicine in the body. This may increase the risk of undesired effects. Your doctor may adjust the dose of this medicine based on your clinical condition.
QT prolongation
QT prolongation is a condition in which your heart muscles take a longer time to recharge between a heartbeat. Pangraf 0.5 MG Capsule may cause QT prolongation and should be used with caution if you have heart problems. Your doctor may suggest tests to monitor the functioning of your heart and electrolyte levels during treatment with this medicine.
Vaccination
Consult your doctor before getting vaccinated during treatment with Pangraf 0.5 MG Capsule. This medicine can alter your body’s response to the vaccine and the vaccine may not work well.
Skin cancer
Pangraf 0.5 MG Capsule should be used with caution as it may increase the risk of skin cancer. Hence, limit your exposure to sunlight and UV light by wearing protective clothing or using sunscreen.

Dosage

Missed Dose
Try not to skip a dose of Pangraf 0.5 MG Capsule. If you miss a dose, take it as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.
Overdose
Never take more than the recommended dose. Seek emergency medical attention in case of an overdose with Pangraf 0.5 MG Capsule.

Interactions

General Instructions
Take Pangraf 0.5 MG Capsule as instructed by your doctor. Do not break, chew, or crush the capsule.

Avoid taking more than the prescribed dose. For the ease of remembering, take it around the same time every day.

Pangraf 0.5 MG Capsule may increase the risk of skin cancer. Hence, limit your exposure to sunlight and UV light by wearing protective clothing or using sunscreen during treatment with this medicine.

Pangraf 0.5 MG Capsule may increase your risk of infections. Consult your doctor if you experience fever, sore throat, cough, mouth sores, etc.

Avoid driving vehicles or operating machines if you feel dizzy or experience blurred vision during treatment with this medicine.

Consult your doctor before getting vaccinated during treatment with Pangraf 0.5 MG Capsule. This medicine can alter your body’s response to the vaccine and the vaccine may not work well.