Panderm + Cream (Terbinafine 1% / Clobetasol 0.05% / Ofloxacin 0.75% / Ornidazole 2%)

Panderm + Cream

Panderm+ Cream helps in the treatment of bacterial infections and fungal infections. It also helps in curing skin infections and dermatoses. It is recommended to apply this cream two times in a day as directed by the doctor.

Panderm Plus Cream contains Clobetasol, Ofloxacin, Ornidazole, Terbinafine as active ingredients. It is a combination of corticosteroids, antifungal, and antibiotics, thus works via multiple mechanisms.

Firstly, it works as an anti-inflammatory by inhibiting the metabolism of arachidonic acid by inhibiting phospholipase A2. Secondly, it decreases ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Micosporum.

The common side effects of Panderm + cream are Rash, Skin Irritation, Burning and others. Take medical help if these side effects do not go away within a few days. It is recommended to consult your doctor about your medical condition.

In case of a missed dose of this drug, you must take it immediately. It is advised to skip the missed dose if it is time for your next scheduled dose. Pregnant or breastfeeding women should apply this medication only after doctor’s consultation as it may leave some kind of side effects.

Use

The most common use of Panderm Cream are:

Dermatitis

Psoriasis

Lichen Planus

Side Effects

Some of the side effects caused by Panderm Plus Cream are:

Application Site Reactions (Burning Sensation)

Dry Skin

Redness Of Skin

Itching Of Skin

Headache

Dosage

Are there any missed dose instructions?

Stick to the time and dosage prescribed by the doctor. Make sure you are taking an adequate amount on time.

Work

Panderm Cream is a combination of corticosteroids, antifungal, and antibiotics, thus works via multiple mechanisms. Firstly, it works as an anti-inflammatory by inhibiting the metabolism of arachidonic acid by inhibiting phospholipase A2 thus inhibits the production of inflammatory mediators like prostaglandins and leukotrienes. Secondly, it decreases ergosterol production by disrupting the activity of cytochrome P450, inhibiting the formation of the cell membrane of susceptible fungi like Candida and Micosporum. Thirdly, it kills them by seeping into their cells through diffusion and damaging DNA and other critical biomolecules through the formation of reactive nitro radicals. Lastly, works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

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